Anticoagulant mechanism, pharmacological activity, and assessment of preclinical safety of a novel fibrin(ogen)olytic serine protease from leaves of Leucas indica

Role of heparin and non heparin binding serpins in coagulation and angiogenesis: A complex interplay

(2016) Teena Bhakuni et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Structural and functional characterization of complex formation between two Kunitz-type serine protease inhibitors from Russell's Viper venom

(2016) Ashis K. Mukherjee et al.   BIOCHIMIE

Purification, characterization and in vitro anticoagulant activity of polysaccharides from Gentiana scabra Bunge roots

(2016) Weirong Cai et al.   CARBOHYDRATE POLYMERS

In Vivo Anticoagulant and Thrombolytic Activities of a Fibrinolytic Serine Protease (Brevithrombolase) With the k-Carrageenan-Induced Rat Tail Thrombosis Model

(2016) Sourav Majumdar et al.   CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS

Unraveling the Proteome Composition and Immuno-profiling of Western India Russell’s Viper Venom for In-Depth Understanding of Its Pharmacological Properties, Clinical Manifestations, and Effective Antivenom Treatment

(2016) Bhargab Kalita et al.   JOURNAL OF PROTEOME RESEARCH

A proteomic analysis of Pakistan Daboia russelii russelii venom and assessment of potency of Indian polyvalent and monovalent antivenom

(2016) Ashis K. Mukherjee et al.   Journal of Proteomics

Acute induction of anomalous and amyloidogenic blood clotting by molecular amplification of highly substoichiometric levels of bacterial lipopolysaccharide

(2016) Etheresia Pretorius et al.   Journal of the Royal Society Interface

Extract from spent hop (Humulus lupulus L.) reduces blood platelet aggregation and improves anticoagulant activity of human endothelial cells in vitro

(2016) Boguslawa Luzak et al.   Journal of Functional Foods

Functional characterizations of interactive recombinant PTEN–silica nanoparticles for potential biomedical applications

(2016) Neha Arora et al.   RSC Advances

Apoptosis induction in human breast cancer (MCF-7) cells by a novel venom l-amino acid oxidase (Rusvinoxidase) is independent of its enzymatic activity and is accompanied by caspase-7 activation and reactive oxygen species production

(2015) Ashis K. Mukherjee et al.   APOPTOSIS

Anticoagulant mechanism and platelet deaggregation property of a non-cytotoxic, acidic phospholipase A2 purified from Indian cobra (Naja naja) venom: Inhibition of anticoagulant activity by low molecular weight heparin

(2015) Sumita Dutta et al.   BIOCHIMIE

A bifunctional protease from green alga Ulva pertusa with anticoagulant properties: partial purification and characterization

(2015) Seong-Ryeoung Kang et al.   JOURNAL OF APPLIED PHYCOLOGY

Structural Characterization of Interaction between Human Ubiquitin-specific Protease 7 and Immediate-Early Protein ICP0 of Herpes Simplex Virus-1

(2015) Alexandra K. Pozhidaeva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization, mechanism of anticoagulant action, and assessment of therapeutic potential of a fibrinolytic serine protease (Brevithrombolase) purified from Brevibacillus brevis strain FF02B

(2014) Sourav Majumdar et al.   BIOCHIMIE

A new peptide (Ruviprase) purified from the venom of Daboia russelii russelii shows potent anticoagulant activity via non-enzymatic inhibition of thrombin and factor Xa

(2014) Rupamoni Thakur et al.   BIOCHIMIE

Novel thrombolytic protease from edible and medicinal plant Aster yomena (Kitam.) Honda with anticoagulant activity: Purification and partial characterization

(2014) Jun-Hui Choi et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Chlorogenic Acid Inhibits Human Platelet Activation and Thrombus Formation

(2014) Eduardo Fuentes et al.   PLoS One

The Pro-Coagulant Fibrinogenolytic Serine Protease Isoenzymes Purified from Daboia russelii russelii Venom Coagulate the Blood through Factor V Activation: Role of Glycosylation on Enzymatic Activity

(2014) Ashis K. Mukherjee   PLoS One

A new C-type lectin (RVsnaclec) purified from venom of Daboia russelii russelii shows anticoagulant activity via inhibition of FXa and concentration-dependent differential response to platelets in a Ca2+-independent manner

(2014) Ashis K. Mukherjee et al.   THROMBOSIS RESEARCH

Biochemical and pharmacological properties of a new thrombin-like serine protease (Russelobin) from the venom of Russell's Viper (Daboia russelii russelii) and assessment of its therapeutic potential

(2013) Ashis K. Mukherjee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Thrombolytic, anticoagulant and antiplatelet activities of codiase, a bi-functional fibrinolytic enzyme from Codium fragile

(2013) Jun-Hui Choi et al.   BIOCHIMIE

Assembly and Activation of Alternative Complement Components on Endothelial Cell-Anchored Ultra-Large Von Willebrand Factor Links Complement and Hemostasis-Thrombosis

(2013) Nancy A. Turner et al.   PLoS One

Targeting factor Xa and thrombin: impact on coagulation and beyond

(2013) Charles T. Esmon   THROMBOSIS AND HAEMOSTASIS

Characterization of a pro-angiogenic, novel peptide from Russell's viper (Daboia russelii russelii) venom

(2013) Ashis K. Mukherjee et al.   TOXICON

Bafibrinase: A non-toxic, non-hemorrhagic, direct-acting fibrinolytic serine protease from Bacillus sp. strain AS-S20-I exhibits in vivo anticoagulant activity and thrombolytic potency

(2012) Ashis K. Mukherjee et al.   BIOCHIMIE

Biochemical characterization and comparative analysis of two distinct serine proteases from Bothrops pirajai snake venom

(2012) Danilo Luccas Menaldo et al.   BIOCHIMIE

Oral Anticoagulant Therapy

(2012) Walter Ageno et al.   CHEST

Direct acting anti-thrombotic serine protease from brown seaweed Costaria costata

(2012) Dae-Won Kim et al.   PROCESS BIOCHEMISTRY

Platelet Glycoprotein VI Dimerization, an Active Process Inducing Receptor Competence, Is an Indicator of Platelet Reactivity

(2011) Stéphane Loyau et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Production of plant proteases in vivo and in vitro — A review

(2011) Nuria González-Rábade et al.   BIOTECHNOLOGY ADVANCES

Elevated fibrinogen causes thrombosis

(2011) R. A. S. Ariens   BLOOD

Causal relationship between hyperfibrinogenemia, thrombosis, and resistance to thrombolysis in mice

(2011) K. R. Machlus et al.   BLOOD

Anti-platelet therapy: cyclo-oxygenase inhibition and the use of aspirin with particular regard to dual anti-platelet therapy

(2011) Timothy D. Warner et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

cAMP regulates ADP-induced HSP27 phosphorylation in human platelets

(2011) Kozawa   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Purification and characterization of a novel, highly potent fibrinolytic enzyme from Paecilomyces tenuipes

(2011) Hoe Chang Kim et al.   PROCESS BIOCHEMISTRY

An acidic phospholipase A2 (RVVA-PLA2-I) purified from Daboia russelli venom exerts its anticoagulant activity by enzymatic hydrolysis of plasma phospholipids and by non-enzymatic inhibition of factor Xa in a phospholipids/Ca2+ independent manner

(2011) Debashree Saikia et al.   TOXICON

Novel Oral Factor Xa and Thrombin Inhibitors in the Management of Thromboembolism

(2010) Bengt I. Eriksson et al.   Annual Review of Medicine

A new role for the A2b adenosine receptor in regulating platelet function

(2010) D. YANG et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Statistical optimization of production, purification and industrial application of a laundry detergent and organic solvent-stable subtilisin-like serine protease (Alzwiprase) from Bacillus subtilis DM-04

(2009) Sudhir K. Rai et al.   BIOCHEMICAL ENGINEERING JOURNAL

Polyphenolic-polysaccharide compounds from selected medicinal plants of Asteraceae and Rosaceae families: Chemical characterization and blood anticoagulant activity

(2009) Izabela Pawlaczyk et al.   CARBOHYDRATE POLYMERS

The Platelet Integrin αIIbβ3 Binds to the RGD and AGD Motifs in Fibrinogen

(2009) Juan Sánchez-Cortés et al.   CHEMISTRY & BIOLOGY

Crinumin, a chymotrypsin-like but glycosylated serine protease from Crinum asiaticum: Purification and physicochemical characterisation

(2009) Kunwar Awaneesh Singh et al.   FOOD CHEMISTRY

Potent antiplatelet activity of sesamol in an in vitro and in vivo model: pivotal roles of cyclic AMP and p38 mitogen-activated protein kinase

(2009) Chao C. Chang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Direct fibrinolytic agents: biochemical attributes, preclinical foundation and clinical potential

(2009) V. J. MARDER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Biochemical and functional properties of a thrombin-like enzyme isolated from Bothrops pauloensis snake venom

(2009) Fábio L.S. Costa et al.   TOXICON

Purification and characterization of fibrinolytic metalloprotease from Perenniporia fraxinea mycelia

(2008) Jae-Sung Kim et al.