Loss of the adaptor protein ShcA in endothelial cells protects against monocyte macrophage adhesion, LDL-oxydation, and atherosclerotic lesion formation

Convergent Signaling Pathways Controlled by LRP1 (Receptor-related Protein 1) Cytoplasmic and Extracellular Domains Limit Cellular Cholesterol Accumulation

(2016) Zeina El Asmar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p66 Shc Couples Mechanical Signals to RhoA through Focal Adhesion Kinase-Dependent Recruitment of p115-RhoGEF and GEF-H1

(2016) Ru-Feng Wu et al.   MOLECULAR AND CELLULAR BIOLOGY

ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types

(2016) Waltraut Lehmann et al.   Nature Communications

An extract from medical leech improve the function of endothelial cells in vitro and attenuates atherosclerosis in ApoE null mice by reducing macrophages in the lesions

(2014) Yao Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cartilage tissue engineering: Molecular control of chondrocyte differentiation for proper cartilage matrix reconstruction

(2014) Magali Demoor et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The Src Homology and Collagen A (ShcA) Adaptor Protein Is Required for the Spatial Organization of the Costamere/Z-disk Network during Heart Development

(2014) Mohamed Mlih et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased monocyte adhesion by endothelial expression of VCAM-1 missense variation in vitro

(2013) Boris Schmitz et al.   ATHEROSCLEROSIS

Epigenetic upregulation of p66shc mediates low-density lipoprotein cholesterol-induced endothelial cell dysfunction

(2012) Young-Rae Kim et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Teaching an old dogma new tricks: twenty years of Shc adaptor signalling

(2012) Melanie K. B. Wills et al.   BIOCHEMICAL JOURNAL

Evolutionary functional analysis and molecular regulation of the ZEB transcription factors

(2012) Alexander Gheldof et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Oxidized Low-Density Lipoprotein Activates p66 Shc via Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1, Protein Kinase C-β, and c-Jun N-Terminal Kinase Kinase in Human Endothelial Cells

(2011) Yi Shi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A novel tyrosine kinase inhibitor restores chondrocyte differentiation and promotes bone growth in a gain-of-function Fgfr3 mouse model

(2011) Aurélie Jonquoy et al.   HUMAN MOLECULAR GENETICS

Differential Signaling by Adaptor Molecules LRP1 and ShcA Regulates Adipogenesis by the Insulin-like Growth Factor-1 Receptor

(2011) Estelle Woldt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IGF-1R signaling in chondrocytes modulates growth plate development by interacting with the PTHrP/Ihh pathway

(2011) Yongmei Wang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Soy phosphatidylcholine inhibited TLR4-mediated MCP-1 expression in vascular cells

(2009) Atsushi Ishikado et al.   ATHEROSCLEROSIS

Angiopoietin-2 Confers Atheroprotection in apoE −/− Mice by Inhibiting LDL Oxidation via Nitric Oxide

(2009) Asif Ahmed et al.   CIRCULATION RESEARCH

Monocyte-Endothelial Cell Interactions in the Development of Atherosclerosis

(2009) Javier Mestas et al.   TRENDS IN CARDIOVASCULAR MEDICINE

The IKK Complex, a Central Regulator of NF- B Activation

(2009) A. Israel   Cold Spring Harbor Perspectives in Biology

The role of the ZEB family of transcription factors in development and disease

(2008) C. Vandewalle et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

p66ShcDeletion Confers Vascular Protection in Advanced Atherosclerosis in Hypercholesterolemic Apolipoprotein E Knockout Mice

(2008) Ines Martin-Padura et al.   ENDOTHELIUM-JOURNAL OF ENDOTHELIAL CELL RESEARCH

LRP1 Controls Intracellular Cholesterol Storage and Fatty Acid Synthesis through Modulation of Wnt Signaling

(2008) Jérome Terrand et al.   JOURNAL OF BIOLOGICAL CHEMISTRY