Discovery of VEGFR2 inhibitors by integrating naïve Bayesian classification, molecular docking and drug screening approaches

VEGFR-2 inhibitors and the therapeutic applications thereof: a patent review (2012-2016)

(2017) Fan-Wei Peng et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Discovery of novel dual VEGFR2 and Src inhibitors using a multistep virtual screening approach

(2017) Shangying Chen et al.   Future Medicinal Chemistry

Fragment-based in silico modeling of multi-target inhibitors against breast cancer-related proteins

(2017) Alejandro Speck-Planche et al.   MOLECULAR DIVERSITY

Drug repurposing in cancer

(2017) Linda Sleire et al.   PHARMACOLOGICAL RESEARCH

Speeding up Early Drug Discovery in Antiviral Research: A Fragment-Based in Silico Approach for the Design of Virtual Anti-Hepatitis C Leads

(2017) Alejandro Speck-Planche et al.   ACS Combinatorial Science

Overexpression of c-Jun contributes to sorafenib resistance in human hepatoma cell lines

(2017) Yuki Haga et al.   PLoS One

Ten years of anti-vascular endothelial growth factor therapy

(2016) Napoleone Ferrara et al.   NATURE REVIEWS DRUG DISCOVERY

Discovery of neuroprotective compounds by machine learning approaches

(2016) Jiansong Fang et al.   RSC Advances

Discovery of Multitarget-Directed Ligands against Alzheimer’s Disease through Systematic Prediction of Chemical–Protein Interactions

(2015) Jiansong Fang et al.   Journal of Chemical Information and Modeling

Recent advances in structure-based drug design and virtual screening of VEGFR tyrosine kinase inhibitors

(2015) Pui Man Hoi et al.   METHODS

Fragment virtual screening based on Bayesian categorization for discovering novel VEGFR-2 scaffolds

(2015) Yanmin Zhang et al.   MOLECULAR DIVERSITY

Discovery of Influenza A virus neuraminidase inhibitors using support vector machine and Naïve Bayesian models

(2015) Wenwen Lian et al.   MOLECULAR DIVERSITY

Why is Tanimoto index an appropriate choice for fingerprint-based similarity calculations?

(2015) Dávid Bajusz et al.   Journal of Cheminformatics

Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen

(2015) Martin Michaelis et al.   Scientific Reports

Consensus models for CDK5 inhibitors in silico and their application to inhibitor discovery

(2014) Jiansong Fang et al.   MOLECULAR DIVERSITY

Predicting mTOR Inhibitors with a Classifier Using Recursive Partitioning and Naïve Bayesian Approaches

(2014) Ling Wang et al.   PLoS One

Drug Repurposing: Translational Pharmacology, Chemistry, Computers and the Clinic

(2013) Naiem Issa et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Predictions of BuChE Inhibitors Using Support Vector Machine and Naive Bayesian Classification Techniques in Drug Discovery

(2013) Jiansong Fang et al.   Journal of Chemical Information and Modeling

An Integrated Virtual Screening Approach for VEGFR-2 Inhibitors

(2013) Yanmin Zhang et al.   Journal of Chemical Information and Modeling

Rilpivirine: a new non-nucleoside reverse transcriptase inhibitor

(2012) M. Sharma et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Structure-Based Design of Novel Class II c-Met Inhibitors: 2. SAR and Kinase Selectivity Profiles of the Pyrazolone Series

(2012) Longbin Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Directory of Useful Decoys, Enhanced (DUD-E): Better Ligands and Decoys for Better Benchmarking

(2012) Michael M. Mysinger et al.   JOURNAL OF MEDICINAL CHEMISTRY

Molecular conformations, interactions, and properties associated with drug efficiency and clinical performance among VEGFR TK inhibitors

(2012) M. McTigue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer heterogeneity: origins and implications for genetic association studies

(2012) Davnah Urbach et al.   TRENDS IN GENETICS

Investigation of a novel molecular descriptor for the lead optimization of 4-aminoquinazolines as vascular endothelial growth factor receptor-2 inhibitors: Application for quantitative structure–activity relationship analysis in lead optimization

(2011) Joel K. Kawakami et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Discovery and selectivity-profiling of 4-benzylamino 1-aza-9-oxafluorene derivatives as lead structures for IGF-1R inhibitors

(2010) Martin Krug et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Angiogenesis as a potential target of pharmaconutrients in cancer therapy

(2010) Virginie Granci et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Pharmacophore modeling and virtual screening studies for new VEGFR-2 kinase inhibitors

(2010) Kyungik Lee et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Toxicities Associated with the Administration of Sorafenib, Sunitinib, and Temsirolimus and Their Management in Patients with Metastatic Renal Cell Carcinoma

(2007) Naeem Bhojani et al.   EUROPEAN UROLOGY