Kinase Control of Latent HIV-1 Infection: PIM-1 Kinase as a Major Contributor to HIV-1 Reactivation

The Receptor Tyrosine Kinase RON Represses HIV-1 Transcription by Targeting RNA Polymerase II Processivity

(2014) A. Klatt et al.   JOURNAL OF IMMUNOLOGY

Unique characteristics of histone deacetylase inhibitors in reactivation of latent HIV-1 in Bcl-2-transduced primary resting CD4+ T cells

(2013) Liang Shan et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

High Levels of CD2 Expression Identify HIV-1 Latently Infected Resting Memory CD4+ T Cells in Virally Suppressed Subjects

(2013) M. Iglesias-Ussel et al.   JOURNAL OF VIROLOGY

Signaling Pathways Differentially Affect RNA Polymerase II Initiation, Pausing, and Elongation Rate in Cells

(2013) Charles G. Danko et al.   MOLECULAR CELL

Highly potent, synthetically accessible prostratin analogs induce latent HIV expression in vitro and ex vivo

(2013) E. J. Beans et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Precise Maps of RNA Polymerase Reveal How Promoters Direct Initiation and Pausing

(2013) H. Kwak et al.   SCIENCE

Stimulation of HIV-1-Specific Cytolytic T Lymphocytes Facilitates Elimination of Latent Viral Reservoir after Virus Reactivation

(2012) Liang Shan et al.   IMMUNITY

Host Factor Transcriptional Regulation Contributes to Preferential Expression of HIV Type 1 in IL-4-Producing CD4 T Cells

(2012) M. Zhang et al.   JOURNAL OF IMMUNOLOGY

Effect of Histone Deacetylase Inhibitors on HIV Production in Latently Infected, Resting CD4+ T Cells From Infected Individuals Receiving Effective Antiretroviral Therapy

(2012) J. Blazkova et al.   JOURNAL OF INFECTIOUS DISEASES

Selected Drugs with Reported Secondary Cell-Differentiating Capacity Prime Latent HIV-1 Infection for Reactivation

(2012) T. Shishido et al.   JOURNAL OF VIROLOGY

Kinase Control Prevents HIV-1 Reactivation in Spite of High Levels of Induced NF-κB Activity

(2012) Frank Wolschendorf et al.   JOURNAL OF VIROLOGY

An AP-1 Binding Site in the Enhancer/Core Element of the HIV-1 Promoter Controls the Ability of HIV-1 To Establish Latent Infection

(2012) A. Duverger et al.   JOURNAL OF VIROLOGY

Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

(2012) N. M. Archin et al.   NATURE

Designed, synthetically accessible bryostatin analogues potently induce activation of latent HIV reservoirs in vitro

(2012) Brian A. DeChristopher et al.   Nature Chemistry

CDK2 Regulates HIV-1 Transcription by Phosphorylation of CDK9 on Serine 90

(2012) Denitra Breuer et al.   Retrovirology

The Evolution of Protein Kinase Inhibitors from Antagonists to Agonists of Cellular Signaling

(2011) Arvin C. Dar et al.   Annual Review of Biochemistry

Repressive LTR Nucleosome Positioning by the BAF Complex Is Required for HIV Latency

(2011) Haleh Rafati et al.   PLOS BIOLOGY

Pausing of RNA Polymerase II Disrupts DNA-Specified Nucleosome Organization to Enable Precise Gene Regulation

(2010) Daniel A. Gilchrist et al.   CELL

Studies of HIV-1 latency in an ex vivo model that uses primary central memory T cells

(2010) Alberto Bosque et al.   METHODS

Retroviral Vectors Induce Epigenetic Chromatin Modifications and IL-10 Production in Transduced B Cells via Activation of Toll-like Receptor 2

(2010) Roxana R Ahangarani et al.   MOLECULAR THERAPY

Antiretroviral Intensification and Valproic Acid Lack Sustained Effect on Residual HIV-1 Viremia or Resting CD4+ Cell Infection

(2010) Nancie M. Archin et al.   PLoS One

Gene regulation by nucleosome positioning

(2010) Lu Bai et al.   TRENDS IN GENETICS

Inhibition of human immunodeficiency virus type-1 by cdk inhibitors

(2010) Irene Guendel et al.   AIDS Research and Therapy

Pim-1 controls NF-κB signalling by stabilizing RelA/p65

(2009) K Nihira et al.   CELL DEATH AND DIFFERENTIATION

Small-molecule screening using a human primary cell model of HIV latency identifies compounds that reverse latency without cellular activation

(2009) Hung-Chih Yang et al.   JOURNAL OF CLINICAL INVESTIGATION

Determinants of the Establishment of Human Immunodeficiency Virus Type 1 Latency

(2009) A. Duverger et al.   JOURNAL OF VIROLOGY

Nucleosome positioning and gene regulation: advances through genomics

(2009) Cizhong Jiang et al.   NATURE REVIEWS GENETICS

Valproic acid without intensified antiviral therapy has limited impact on persistent HIV infection of resting CD4+ T cells

(2008) Nancy M Archin et al.   AIDS

Induction of HIV-1 latency and reactivation in primary memory CD4+ T cells

(2008) A. Bosque et al.   BLOOD

Docking Study Yields Four Novel Inhibitors of the Protooncogene Pim-1 Kinase†

(2008) Albert C. Pierce et al.   JOURNAL OF MEDICINAL CHEMISTRY