Systemic DPP4 activity is reduced during primary HIV-1 infection and is associated with intestinal RORC+ CD4+ cell levels: a surrogate marker candidate of HIV-induced intestinal damage

Persistent, Albeit Reduced, Chronic Inflammation in Persons Starting Antiretroviral Therapy in Acute HIV Infection

(2016) Irini Sereti et al.   CLINICAL INFECTIOUS DISEASES

Non-human primates in HIV research: Achievements, limits and alternatives

(2016) Thalía Garcia-Tellez et al.   INFECTION GENETICS AND EVOLUTION

Recent developments in the effort to cure HIV infection: going beyond N = 1

(2016) Janet D. Siliciano et al.   JOURNAL OF CLINICAL INVESTIGATION

Enhancement of Microbiota in Healthy Macaques Results in Beneficial Modulation of Mucosal and Systemic Immune Function

(2016) Jennifer A. Manuzak et al.   JOURNAL OF IMMUNOLOGY

Gut Mucosal Barrier Dysfunction, Microbial Dysbiosis, and Their Role in HIV-1 Disease Progression

(2016) Joseph C. Mudd et al.   JOURNAL OF INFECTIOUS DISEASES

Effects of Fecal Microbial Transplantation on Microbiome and Immunity in Simian Immunodeficiency Virus-Infected Macaques

(2016) Tiffany Hensley-McBain et al.   JOURNAL OF VIROLOGY

Microbial translocation and microbiome dysbiosis in HIV-associated immune activation

(2016) Alexander S. Zevin et al.   Current Opinion in HIV and AIDS

Elevated Basal Pre-infection CXCL10 in Plasma and in the Small Intestine after Infection Are Associated with More Rapid HIV/SIV Disease Onset

(2016) Mickaël J. Ploquin et al.   PLoS Pathogens

Association of microbial translocation biomarkers with clinical outcome in controllers HIV-infected patients

(2015) Agathe León et al.   AIDS

Impact of the Timing of Initiation of Antiretroviral Therapy During Primary HIV-1 Infection on the Decay of Cell-Associated HIV-DNA

(2015) Moussa Laanani et al.   CLINICAL INFECTIOUS DISEASES

High expression of CD26 accurately identifies human bacteria-reactive MR1-restricted MAIT cells

(2015) Prabhat K. Sharma et al.   IMMUNOLOGY

Interleukin-21 combined with ART reduces inflammation and viral reservoir in SIV-infected macaques

(2015) Luca Micci et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-21 and probiotic therapy improve Th17 frequencies, microbial translocation and microbiome in ARV-treated, SIV-infected macaques

(2015) A M Ortiz et al.   Mucosal Immunology

Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy

(2015) Rosa Barreira da Silva et al.   NATURE IMMUNOLOGY

HIV reservoirs: what, where and how to target them

(2015) Melissa J. Churchill et al.   NATURE REVIEWS MICROBIOLOGY

Probiotics Reduce Inflammation in Antiretroviral Treated, HIV-Infected Individuals: Results of the “Probio-HIV” Clinical Trial

(2015) Gabriella d’Ettorre et al.   PLoS One

Dynamic Changes of Post-Translationally Modified Forms of CXCL10 and Soluble DPP4 in HCV Subjects Receiving Interferon-Free Therapy

(2015) Eric G. Meissner et al.   PLoS One

Late Antiretroviral Therapy (ART) Initiation Is Associated with Long-Term Persistence of Systemic Inflammation and Metabolic Abnormalities

(2015) Mathilde Ghislain et al.   PLoS One

Increased Plasma DPP4 Activity Is Predictive of Prediabetes and Type 2 Diabetes Onset in Chinese Over a Four-Year Period: Result From the China National Diabetes and Metabolic Disorders Study

(2014) Tianpeng Zheng et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Early microbial translocation blockade reduces SIV-mediated inflammation and viral replication

(2014) Jan Kristoff et al.   JOURNAL OF CLINICAL INVESTIGATION

Rifaximin has a Marginal Impact on Microbial Translocation, T-cell Activation and Inflammation in HIV-Positive Immune Non-responders to Antiretroviral Therapy – ACTG A5286

(2014) Allan R. Tenorio et al.   JOURNAL OF INFECTIOUS DISEASES

Sevelamer Does Not Decrease Lipopolysaccharide or Soluble CD14 Levels But Decreases Soluble Tissue Factor, Low-Density Lipoprotein (LDL) Cholesterol, and Oxidized LDL Cholesterol Levels in Individuals With Untreated HIV Infection

(2014) Netanya G. Sandler et al.   JOURNAL OF INFECTIOUS DISEASES

Towards a cure for HIV—are we making progress?

(2014) Sharon R Lewin et al.   LANCET

HIV infection: epidemiology, pathogenesis, treatment, and prevention

(2014) Gary Maartens et al.   LANCET

Immune responses during spontaneous control of HIV and AIDS: what is the hope for a cure?

(2014) A. Saez-Cirion et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The Immunologic Effects of Mesalamine in Treated HIV-Infected Individuals with Incomplete CD4+ T Cell Recovery: A Randomized Crossover Trial

(2014) Ma Somsouk et al.   PLoS One

Innate Immune Responses and Rapid Control of Inflammation in African Green Monkeys Treated or Not with Interferon-Alpha during Primary SIVagm Infection

(2014) Béatrice Jacquelin et al.   PLoS Pathogens

Initiation of ART during Early Acute HIV Infection Preserves Mucosal Th17 Function and Reverses HIV-Related Immune Activation

(2014) Alexandra Schuetz et al.   PLoS Pathogens

Severity of Cardiovascular Disease Outcomes Among Patients With HIV Is Related to Markers of Inflammation and Coagulation

(2014) Anna D. Nordell et al.   Journal of the American Heart Association

Predicting risk of cancer during HIV infection

(2013) Álvaro H. Borges et al.   AIDS

Elevated IP10 levels are associated with immune activation and low CD4+ T-cell counts in HIV controller patients

(2013) Nicolas Noel et al.   AIDS

Low DPP4 expression and activity in multiple sclerosis

(2013) Marta Tejera-Alhambra et al.   CLINICAL IMMUNOLOGY

CXCL10 antagonism and plasma sDPPIV correlate with increasing liver disease in chronic HCV genotype 4 infected patients

(2013) Dina Ragab et al.   CYTOKINE

HIV-associated chronic immune activation

(2013) Mirko Paiardini et al.   IMMUNOLOGICAL REVIEWS

CD26/DPP4 Levels in Peripheral Blood and T Cells in Patients With Type 2 Diabetes Mellitus

(2013) Sang Ah Lee et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Evidence for Innate Immune System Activation in HIV Type 1–Infected Elite Controllers

(2013) Sonya Krishnan et al.   JOURNAL OF INFECTIOUS DISEASES

Barriers to a cure for HIV: new ways to target and eradicate HIV-1 reservoirs

(2013) Christine Katlama et al.   LANCET

Past, present and future: 30 years of HIV research

(2013) Françoise Barré-Sinoussi et al.   NATURE REVIEWS MICROBIOLOGY

Impact of Soluble CD26 on Treatment Outcome and Hepatitis C Virus-Specific T Cells in Chronic Hepatitis C Virus Genotype 1 Infection

(2013) Jonas Söderholm et al.   PLoS One

Genome-Wide Association Study on the Development of Cross-Reactive Neutralizing Antibodies in HIV-1 Infected Individuals

(2013) Zelda Euler et al.   PLoS One

Maintenance of Intestinal Th17 Cells and Reduced Microbial Translocation in SIV-infected Rhesus Macaques Treated with Interleukin (IL)-21

(2013) Suresh Pallikkuth et al.   PLoS Pathogens

The Th17/Treg Ratio, IL-1RA and sCD14 Levels in Primary HIV Infection Predict the T-cell Activation Set Point in the Absence of Systemic Microbial Translocation

(2013) Mathieu F. Chevalier et al.   PLoS Pathogens

Human Th17 Cells Express High Levels of Enzymatically Active Dipeptidylpeptidase IV (CD26)

(2012) B. Bengsch et al.   JOURNAL OF IMMUNOLOGY

Microarray Analysis of HIV Resistant Female Sex Workers Reveal a Gene Expression Signature Pattern Reminiscent of a Lowered Immune Activation State

(2012) Elijah M. Songok et al.   PLoS One

Acute Plasma Biomarkers of T Cell Activation Set-Point Levels and of Disease Progression in HIV-1 Infection

(2012) Anne-Sophie Liovat et al.   PLoS One

SIV Replication in the Infected Rhesus Macaque Is Limited by the Size of the Preexisting TH17 Cell Compartment

(2012) D. J. Hartigan-O'Connor et al.   Science Translational Medicine

Microbial translocation predicts disease progression of HIV-infected antiretroviral-naive patients with high CD4+ cell count

(2011) Giulia Marchetti et al.   AIDS

Immune deficiency could be an early risk factor for altered insulin sensitivity in antiretroviral-naive HIV-1-infected patients: the ANRS COPANA cohort

(2011) Faroudy Boufassa et al.   ANTIVIRAL THERAPY

Higher Levels of CRP, D-dimer, IL-6, and Hyaluronic Acid Before Initiation of Antiretroviral Therapy (ART) Are Associated With Increased Risk of AIDS or Death

(2011) David R. Boulware et al.   JOURNAL OF INFECTIOUS DISEASES

Evidence for an antagonist form of the chemokine CXCL10 in patients chronically infected with HCV

(2010) Armanda Casrouge et al.   JOURNAL OF CLINICAL INVESTIGATION

CD26/dipeptidyl peptidase IV (CD26/DPPIV) is highly expressed in peripheral blood of HIV-1 exposed uninfected Female sex workers

(2010) Elijah M Songok et al.   Virology Journal

Serum level of CD26 predicts time to first treatment in early B-chronic lymphocytic leukemia

(2009) Stefano Molica et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Serum Immune Activation Markers Are Persistently Increased in Patients with HIV Infection after 6 Years of Antiretroviral Therapy despite Suppression of Viral Replication and Reconstitution of CD4+T Cells

(2009) Martyn A. French et al.   JOURNAL OF INFECTIOUS DISEASES

Revisiting an old acquaintance: CD26 and its molecular mechanisms in T cell function

(2008) Kei Ohnuma et al.   TRENDS IN IMMUNOLOGY

Relationship between T Cell Activation and CD4+T Cell Count in HIV‐Seropositive Individuals with Undetectable Plasma HIV RNA Levels in the Absence of Therapy

(2007) Peter W. Hunt et al.   JOURNAL OF INFECTIOUS DISEASES