Acetylshikonin from Zicao ameliorates renal dysfunction and fibrosis in diabetic mice by inhibiting TGF-β1/Smad pathway

Role of endothelial-to-mesenchymal transition induced by TGF-β1 in transplant kidney interstitial fibrosis

(2017) Zijie Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Acetylshikonin inhibits growth of oral squamous cell carcinoma by inducing apoptosis

(2016) Da Jeong Kim et al.   ARCHIVES OF ORAL BIOLOGY

Acetylshikonin from Zicao exerts antifertility effects at high dose in rats by suppressing the secretion of GTH

(2016) Yu He et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Impaired Mechanics of Left Ventriculo-Atrial Coupling in Patients With Diabetic Nephropathy

(2016) Yasuhide Mochizuki et al.   CIRCULATION JOURNAL

Renoprotective effect of berberineviaregulating the PGE2-EP1-Gαq-Ca2+signalling pathway in glomerular mesangial cells of diabetic rats

(2016) Wei-Jian Ni et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Efficacy of Acetylshikonin in Preventing Obesity and Hepatic Steatosis in db/db Mice

(2016) Mei-Ling Su et al.   MOLECULES

Acetylshikonin from Zicao Prevents Obesity in Rats on a High-Fat Diet by Inhibiting Lipid Accumulation and Inducing Lipolysis

(2016) Meiling Su et al.   PLoS One

Shikonin Suppresses NLRP3 and AIM2 Inflammasomes by Direct Inhibition of Caspase-1

(2016) Jernej Zorman et al.   PLoS One

Apelin promotes diabetic nephropathy by inducing podocyte dysfunction via inhibiting proteasome activities

(2015) Caixia Guo et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Icariside II ameliorates diabetic nephropathy in streptozotocin-induced diabetic rats

(2015) Hongen Lei et al.   Drug Design Development and Therapy

Arnebin-1 promotes the angiogenesis of human umbilical vein endothelial cells and accelerates the wound healing process in diabetic rats

(2014) Zhi Zeng et al.   JOURNAL OF ETHNOPHARMACOLOGY

Which Indexes Are the Most Important Risk Factor for Cardiorenal Events in Type 2 Diabetic Patients?

(2013) Tatsuo Kawai et al.   CIRCULATION JOURNAL

Inhibition of MAPK-mediated ACE expression by compound C66 prevents STZ-induced diabetic nephropathy

(2013) Yong Pan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Pharmacological Properties of Shikonin – A Review of Literature since 2002

(2013) Isabel Andújar et al.   PLANTA MEDICA

Renoprotective effects of (+)-catechin in streptozotocin-induced diabetic rat model

(2012) Sudha P. Chennasamudram et al.   NUTRITION RESEARCH

Beneficial effect of myricetin on renal functions in streptozotocin-induced diabetes

(2011) Filiz Ozcan et al.   CLINICAL AND EXPERIMENTAL MEDICINE

Transforming growth factor-β/Smad signalling in diabetic nephropathy

(2011) Hui Yao Lan   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Activation of Peroxisome Proliferator–Activated Receptor δ Inhibits Streptozotocin-Induced Diabetic Nephropathy Through Anti-Inflammatory Mechanisms in Mice

(2011) Yuichi Matsushita et al.   DIABETES

Risk for ESRD in Type 1 Diabetes Remains High Despite Renoprotection

(2011) E. T. Rosolowsky et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Protective effect of tetramethylpyrazine isolated from Ligusticum chuanxiong on nephropathy in rats with streptozotocin-induced diabetes

(2011) Qi-Hong Yang et al.   PHYTOMEDICINE

Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosis

(2010) Sonali Sonnylal et al.   ARTHRITIS AND RHEUMATISM

The Protective Role of Smad7 in Diabetic Kidney Disease: Mechanism and Therapeutic Potential

(2010) H. Y. Chen et al.   DIABETES

NF- B in Renal Inflammation

(2010) A. B. Sanz et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

TGF-β and fibrosis in different organs — molecular pathway imprints

(2009) Dirk Pohlers et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

New Insights into Epithelial-Mesenchymal Transition in Kidney Fibrosis

(2009) Y. Liu   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Shikonin derivatives inhibited LPS-induced NOS in RAW 264.7 cells via downregulation of MAPK/NF-κB signaling

(2008) Yu Wen Cheng et al.   JOURNAL OF ETHNOPHARMACOLOGY

The Role of Inflammatory Cytokines in Diabetic Nephropathy

(2008) J. F. Navarro-Gonzalez et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY