Adult Hippocampal Neurogenesis: Regulation and Possible Functional and Clinical Correlates

Human Hippocampal Neurogenesis Persists throughout Aging

(2018) Maura Boldrini et al.   Cell Stem Cell

Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults

(2018) Shawn F. Sorrells et al.   NATURE

Questioning human neurogenesis

(2018) Jason S. Snyder   NATURE

Adult hippocampal neurogenesis and cognitive flexibility — linking memory and mood

(2017) Christoph Anacker et al.   NATURE REVIEWS NEUROSCIENCE

Adult-born neurons modify excitatory synaptic transmission to existing neurons

(2017) Elena W Adlaf et al.   eLife

The modulation of adult neuroplasticity is involved in the mood-improving actions of atypical antipsychotics in an animal model of depression

(2017) M Morais et al.   Translational Psychiatry

Pattern Separation: A Potential Marker of Impaired Hippocampal Adult Neurogenesis in Major Depressive Disorder

(2017) Kellen Gandy et al.   Frontiers in Neuroscience

Can physical exercise in old age improve memory and hippocampal function?

(2016) Emrah Duzel et al.   BRAIN

Activation of local inhibitory circuits in the dentate gyrus by adult-born neurons

(2016) Liam J. Drew et al.   HIPPOCAMPUS

Infantile amnesia reflects a developmental critical period for hippocampal learning

(2016) Alessio Travaglia et al.   NATURE NEUROSCIENCE

Caloric restriction in young rats disturbs hippocampal neurogenesis and spatial learning

(2016) Armando Cardoso et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Running rewires the neuronal network of adult-born dentate granule cells

(2016) Carmen Vivar et al.   NEUROIMAGE

Relationships of peripheral IGF-1, VEGF and BDNF levels to exercise-related changes in memory, hippocampal perfusion and volumes in older adults

(2016) Anne Maass et al.   NEUROIMAGE

Modulating Neuronal Competition Dynamics in the Dentate Gyrus to Rejuvenate Aging Memory Circuits

(2016) Kathleen M. McAvoy et al.   NEURON

Distinct Contribution of Adult-Born Hippocampal Granule Cells to Context Encoding

(2016) Nathan B. Danielson et al.   NEURON

Human adult neurogenesis across the ages: An immunohistochemical study

(2016) C. V. Dennis et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Low excitatory innervation balances high intrinsic excitability of immature dentate neurons

(2016) Cristina V. Dieni et al.   Nature Communications

Neurogenesis-mediated forgetting minimizes proactive interference

(2016) Jonathan R. Epp et al.   Nature Communications

Grafted Subventricular Zone Neural Stem Cells Display Robust Engraftment and Similar Differentiation Properties and Form New Neurogenic Niches in the Young and Aged Hippocampus

(2016) Ashok K. Shetty et al.   Stem Cells Translational Medicine

Preserved neurogenesis in non-demented individuals with AD neuropathology

(2016) David Briley et al.   Scientific Reports

Dynamic role of adult-born dentate granule cells in memory processing

(2015) Emilio Kropff et al.   CURRENT OPINION IN NEUROBIOLOGY

Depression: from psychopathology to pathophysiology

(2015) Catherine Belzung et al.   CURRENT OPINION IN NEUROBIOLOGY

Human neural stem cells improve cognition and promote synaptic growth in two complementary transgenic models of Alzheimer's disease and neuronal loss

(2015) Rahasson R. Ager et al.   HIPPOCAMPUS

Age differences in hippocampal subfield volumes from childhood to late adulthood

(2015) Ana M. Daugherty et al.   HIPPOCAMPUS

Chronic treatment with tandospirone, a serotonin 1A receptor partial agonist, inhibits psychosocial stress-induced changes in hippocampal neurogenesis and behavior

(2015) Yusuke Murata et al.   JOURNAL OF AFFECTIVE DISORDERS

Molecular mechanisms in the regulation of adult neurogenesis during stress

(2015) Martin Egeland et al.   NATURE REVIEWS NEUROSCIENCE

The aged brain: genesis and fate of residual progenitor cells in the subventricular zone

(2015) Vivian Capilla-Gonzalez et al.   Frontiers in Cellular Neuroscience

Activity Dependency and Aging in the Regulation of Adult Neurogenesis

(2015) Gerd Kempermann   Cold Spring Harbor Perspectives in Biology

Maturation and Functional Integration of New Granule Cells into the Adult Hippocampus

(2015) Nicolas Toni et al.   Cold Spring Harbor Perspectives in Biology

Adult Neurogenesis in Humans

(2015) Olaf Bergmann et al.   Cold Spring Harbor Perspectives in Biology

Adult Neurogenesis in Neurodegenerative Diseases: Figure 1.

(2015) Beate Winner et al.   Cold Spring Harbor Perspectives in Biology

Regulation of Adult Neurogenesis and Plasticity by (Early) Stress, Glucocorticoids, and Inflammation

(2015) Paul J. Lucassen et al.   Cold Spring Harbor Perspectives in Biology

Adult Neurogenesis in Humans- Common and Unique Traits in Mammals

(2015) Aurélie Ernst et al.   PLOS BIOLOGY

The hippocampus and exercise: histological correlates of MR-detected volume changes

(2014) Sarah V. Biedermann et al.   Brain Structure & Function

Neurogenesis in the Striatum of the Adult Human Brain

(2014) Aurélie Ernst et al.   CELL

Functional dissociation of adult-born neurons along the dorsoventral axis of the dentate gyrus

(2014) Melody V. Wu et al.   HIPPOCAMPUS

Pattern separation of emotional information in hippocampal dentate and CA3

(2014) Stephanie L. Leal et al.   HIPPOCAMPUS

The organization of the stress system and its dysregulation in depressive illness

(2014) P W Gold   MOLECULAR PSYCHIATRY

Regulation and Function of Adult Neurogenesis: From Genes to Cognition

(2014) James B. Aimone et al.   PHYSIOLOGICAL REVIEWS

The Different Roles of Glucocorticoids in the Hippocampus and Hypothalamus in Chronic Stress-Induced HPA Axis Hyperactivity

(2014) Li-Juan Zhu et al.   PLoS One

Hippocampal Neurogenesis Regulates Forgetting During Adulthood and Infancy

(2014) K. G. Akers et al.   SCIENCE

Temporally selective contextual encoding in the dentate gyrus of the hippocampus

(2014) L.M. Rangel et al.   Nature Communications

Role of adult neurogenesis in hippocampal-cortical memory consolidation

(2014) Takashi Kitamura et al.   Molecular Brain

Neuropathology of stress

(2013) Paul J. Lucassen et al.   ACTA NEUROPATHOLOGICA

Temporal associations for spatial events: The role of the dentate gyrus

(2013) Andrea M. Morris et al.   BEHAVIOURAL BRAIN RESEARCH

Quetiapine add-on therapy improves the depressive behaviors and hippocampal neurogenesis in fluoxetine treatment resistant depressive rats

(2013) Ying Wang et al.   BEHAVIOURAL BRAIN RESEARCH

A possible negative influence of depression on the ability to overcome memory interference

(2013) Don J. Shelton et al.   BEHAVIOURAL BRAIN RESEARCH

Sexual activity counteracts the suppressive effects of chronic stress on adult hippocampal neurogenesis and recognition memory

(2013) Jong-In Kim et al.   BRAIN RESEARCH

Dynamics of Hippocampal Neurogenesis in Adult Humans

(2013) Kirsty L. Spalding et al.   CELL

Exercise boosts hippocampal volume by preventing early age-related gray matter loss

(2013) Johannes Fuss et al.   HIPPOCAMPUS

Distinct Determinants of Sparse Activation during Granule Cell Maturation

(2013) C. V. Dieni et al.   JOURNAL OF NEUROSCIENCE

Serotonin Is Required for Exercise-Induced Adult Hippocampal Neurogenesis

(2013) F. Klempin et al.   JOURNAL OF NEUROSCIENCE

In vivo imaging of adult human hippocampal neurogenesis: progress, pitfalls and promise

(2013) N F Ho et al.   MOLECULAR PSYCHIATRY

Glucocorticoid receptor protein expression in human hippocampus; stability with age

(2013) Qian Wang et al.   NEUROBIOLOGY OF AGING

Differential Control of Learning and Anxiety along the Dorsoventral Axis of the Dentate Gyrus

(2013) Mazen A. Kheirbek et al.   NEURON

Hippocampal Granule Neuron Number and Dentate Gyrus Volume in Antidepressant-Treated and Untreated Major Depression

(2013) Maura Boldrini et al.   NEUROPSYCHOPHARMACOLOGY

Neurogenesis along the septo-temporal axis of the hippocampus: Are depression and the action of antidepressants region-specific?

(2013) A. Tanti et al.   NEUROSCIENCE

Stress, serotonin, and hippocampal neurogenesis in relation to depression and antidepressant effects

(2013) Ian Mahar et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Hippocampal Neurogenesis Levels Predict WATERMAZE Search Strategies in the Aging Brain

(2013) Joana Gil-Mohapel et al.   PLoS One

Hippocampal neurogenesis and forgetting

(2013) Paul W. Frankland et al.   TRENDS IN NEUROSCIENCES

Adult neurogenesis modifies excitability of the dentate gyrus

(2013) Taruna Ikrar et al.   Frontiers in Neural Circuits

Selection of distinct populations of dentate granule cells in response to inputs as a mechanism for pattern separation in mice

(2013) Wei Deng et al.   eLife

Neurobiological markers of exercise-related brain plasticity in older adults

(2012) Michelle W. Voss et al.   BRAIN BEHAVIOR AND IMMUNITY

Neural Stem Cells and Neurogenesis in the Adult

(2012) Christian Göritz et al.   Cell Stem Cell

Adult-born hippocampal neurons promote cognitive flexibility in mice

(2012) Nesha S. Burghardt et al.   HIPPOCAMPUS

Infantile amnesia: A neurogenic hypothesis

(2012) S. A. Josselyn et al.   LEARNING & MEMORY

Neurogenesis and generalization: a new approach to stratify and treat anxiety disorders

(2012) Mazen A Kheirbek et al.   NATURE NEUROSCIENCE

New neurons for 'survival of the fittest'

(2012) Gerd Kempermann   NATURE REVIEWS NEUROSCIENCE

Neurotrophin regulation of neural circuit development and function

(2012) Hyungju Park et al.   NATURE REVIEWS NEUROSCIENCE

Glucocorticoid regulation of brain-derived neurotrophic factor: Relevance to hippocampal structural and functional plasticity

(2012) D. Suri et al.   NEUROSCIENCE

Unique Processing During a Period of High Excitation/Inhibition Balance in Adult-Born Neurons

(2012) Antonia Marín-Burgin et al.   SCIENCE

Phenotypic and gene expression modification with normal brain aging in GFAP-positive astrocytes and neural stem cells

(2011) Giovanna M. Bernal et al.   AGING CELL

Modeling new neuron function: a history of using computational neuroscience to study adult neurogenesis

(2011) James B. Aimone et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Reduction in hippocampal neurogenesis after social defeat is long-lasting and responsive to late antidepressant treatment

(2011) P. Van Bokhoven et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Neurogenesis and affective disorders

(2011) Benjamin A. Samuels et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Neurodegenerative disease and adult neurogenesis

(2011) Beate Winner et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Comparing adult hippocampal neurogenesis in mammalian species and orders: influence of chronological age and life history stage

(2011) Irmgard Amrein et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Seven principles in the regulation of adult neurogenesis

(2011) Gerd Kempermann   EUROPEAN JOURNAL OF NEUROSCIENCE

Stress, stress hormones, and adult neurogenesis

(2011) Timothy J. Schoenfeld et al.   EXPERIMENTAL NEUROLOGY

The acute glucocorticoid stress response does not differentiate between rewarding and aversive social stimuli in rats

(2011) Bauke Buwalda et al.   HORMONES AND BEHAVIOR

Posttraining Ablation of Adult-Generated Neurons Degrades Previously Acquired Memories

(2011) M. Arruda-Carvalho et al.   JOURNAL OF NEUROSCIENCE

Adult hippocampal neurogenesis and its role in Alzheimer's disease

(2011) Yangling Mu et al.   Molecular Neurodegeneration

Basolateral amygdala regulation of adult hippocampal neurogenesis and fear-related activation of newborn neurons

(2011) E D Kirby et al.   MOLECULAR PSYCHIATRY

Antidepressants recruit new neurons to improve stress response regulation

(2011) A Surget et al.   MOLECULAR PSYCHIATRY

Adult hippocampal neurogenesis buffers stress responses and depressive behaviour

(2011) Jason S. Snyder et al.   NATURE

Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation

(2011) Amar Sahay et al.   NATURE

Corridors of migrating neurons in the human brain and their decline during infancy

(2011) Nader Sanai et al.   NATURE

Activation and survival of immature neurons in the dentate gyrus with spatial memory is dependent on time of exposure to spatial learning and age of cells at examination

(2011) Jonathan R. Epp et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Resolving New Memories: A Critical Look at the Dentate Gyrus, Adult Neurogenesis, and Pattern Separation

(2011) James B. Aimone et al.   NEURON

Pattern Separation: A Common Function for New Neurons in Hippocampus and Olfactory Bulb

(2011) Amar Sahay et al.   NEURON

The neurogenesis hypothesis of affective and anxiety disorders: Are we mistaking the scaffolding for the building?

(2011) David Petrik et al.   NEUROPHARMACOLOGY

Maturation time of new granule cells in the dentate gyrus of adult macaque monkeys exceeds six months

(2011) S. J. Kohler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exercise training increases size of hippocampus and improves memory

(2011) K. I. Erickson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hippocampal Plasticity in Response to Exercise in Schizophrenia

(2010) Frank-Gerald Pajonk et al.   ARCHIVES OF GENERAL PSYCHIATRY

Emotion and episodic memory in neuropsychiatric disorders

(2010) Ekrem Dere et al.   BEHAVIOURAL BRAIN RESEARCH

Functional convergence of developmentally and adult-generated granule cells in dentate gyrus circuits supporting hippocampus-dependent memory

(2010) Scellig S.D. Stone et al.   HIPPOCAMPUS

Effects of adult-generated granule cells on coordinated network activity in the dentate gyrus

(2010) Clay O. Lacefield et al.   HIPPOCAMPUS

Adult-born neurons are necessary for extended contextual discrimination

(2010) Sophie Tronel et al.   HIPPOCAMPUS

Pattern separation deficits associated with increased hippocampal CA3 and dentate gyrus activity in nondemented older adults

(2010) Michael A. Yassa et al.   HIPPOCAMPUS

Brain-Derived Neurotrophic Factor Is Associated with Age-Related Decline in Hippocampal Volume

(2010) K. I. Erickson et al.   JOURNAL OF NEUROSCIENCE

Neural mechanisms of ageing and cognitive decline

(2010) Nicholas A. Bishop et al.   NATURE

New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?

(2010) Wei Deng et al.   NATURE REVIEWS NEUROSCIENCE

Are the Dorsal and Ventral Hippocampus Functionally Distinct Structures?

(2010) Michael S. Fanselow et al.   NEURON

Peripheral BDNF Produces Antidepressant-Like Effects in Cellular and Behavioral Models

(2010) Heath D Schmidt et al.   NEUROPSYCHOPHARMACOLOGY

Chronic high corticosterone reduces neurogenesis in the dentate gyrus of adult male and female rats

(2010) S. Brummelte et al.   NEUROSCIENCE

Murine Features of Neurogenesis in the Human Hippocampus across the Lifespan from 0 to 100 Years

(2010) Rolf Knoth et al.   PLoS One

Sexual Experience Promotes Adult Neurogenesis in the Hippocampus Despite an Initial Elevation in Stress Hormones

(2010) Benedetta Leuner et al.   PLoS One

Running enhances spatial pattern separation in mice

(2010) D. J. Creer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The glucocorticoid receptor: Pivot of depression and of antidepressant treatment?

(2010) Christoph Anacker et al.   PSYCHONEUROENDOCRINOLOGY

When neurogenesis encounters aging and disease

(2010) Orly Lazarov et al.   TRENDS IN NEUROSCIENCES

Overgeneralization of Conditioned Fear as a Pathogenic Marker of Panic Disorder

(2009) Shmuel Lissek et al.   AMERICAN JOURNAL OF PSYCHIATRY

Decline in serotonergic firing activity and desensitization of 5-HT1A autoreceptors after chronic unpredictable stress

(2009) Francis Rodriguez Bambico et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

The partial 5-HT1A receptor agonist buspirone enhances neurogenesis in the opossum (Monodelphis domestica)

(2009) Marta Grabiec et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Evidence for a release of brain-derived neurotrophic factor from the brain during exercise

(2009) Peter Rasmussen et al.   EXPERIMENTAL PHYSIOLOGY

Functional analysis of neurovascular adaptations to exercise in the dentate gyrus of young adult mice associated with cognitive gain

(2009) Peter J. Clark et al.   HIPPOCAMPUS

Physical exercise leads to rapid adaptations in hippocampal vasculature: Temporal dynamics and relationship to cell proliferation and neurogenesis

(2009) Karin Van der Borght et al.   HIPPOCAMPUS

Adult-Born Hippocampal Dentate Granule Cells Undergoing Maturation Modulate Learning and Memory in the Brain

(2009) W. Deng et al.   JOURNAL OF NEUROSCIENCE

Visual object pattern separation deficits in nondemented older adults

(2009) C. K. Toner et al.   LEARNING & MEMORY

Adult hippocampal neurogenesis is involved in anxiety-related behaviors

(2009) J-M Revest et al.   MOLECULAR PSYCHIATRY

Neurogenesis-Dependent and -Independent Effects of Fluoxetine in an Animal Model of Anxiety/Depression

(2009) Denis J. David et al.   NEURON

Immune Activation in Brain Aging and Neurodegeneration: Too Much or Too Little?

(2009) Kurt M. Lucin et al.   NEURON

Computational Influence of Adult Neurogenesis on Memory Encoding

(2009) James B. Aimone et al.   NEURON

Ambiguous-Cue Interpretation is Biased Under Stress- and Depression-Like States in Rats

(2009) Thomas Enkel et al.   NEUROPSYCHOPHARMACOLOGY

Antidepressants increase neural progenitor cells in the human hippocampus

(2009) Maura Boldrini et al.   NEUROPSYCHOPHARMACOLOGY

Suppression of adult neurogenesis leads to an increased hypothalamo-pituitary-adrenal axis response

(2009) Robert J. Schloesser et al.   NEUROREPORT

Chronic but not acute foot-shock stress leads to temporary suppression of cell proliferation in rat hippocampus

(2009) G. Dagytė et al.   NEUROSCIENCE

Adult-Generated Hippocampal Neurons Allow the Flexible Use of Spatially Precise Learning Strategies

(2009) Alexander Garthe et al.   PLoS One

Reliable Activation of Immature Neurons in the Adult Hippocampus

(2009) Lucas A. Mongiat et al.   PLoS One

A Functional Role for Adult Hippocampal Neurogenesis in Spatial Pattern Separation

(2009) C. D. Clelland et al.   SCIENCE

Neurons born in the adult dentate gyrus form functional synapses with target cells

(2008) Nicolas Toni et al.   NATURE NEUROSCIENCE

Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain

(2008) Itaru Imayoshi et al.   NATURE NEUROSCIENCE

Neurogenesis and Exercise: Past and Future Directions

(2008) Henriette van Praag   NEUROMOLECULAR MEDICINE

TrkB Regulates Hippocampal Neurogenesis and Governs Sensitivity to Antidepressive Treatment

(2008) Yun Li et al.   NEURON

Transcriptional regulation at a HTR1A polymorphism associated with mental illness

(2008) Brice Le François et al.   NEUROPHARMACOLOGY

Spatial Relational Memory Requires Hippocampal Adult Neurogenesis

(2008) David Dupret et al.   PLoS One

Pattern Separation in the Human Hippocampal CA3 and Dentate Gyrus

(2008) A. Bakker et al.   SCIENCE

The neurogenic reserve hypothesis: what is adult hippocampal neurogenesis good for?

(2008) Gerd Kempermann   TRENDS IN NEUROSCIENCES

Be smart, exercise your heart: exercise effects on brain and cognition

(2007) Charles H. Hillman et al.   NATURE REVIEWS NEUROSCIENCE