How single mutations affect viral escape from broad and narrow antibodies to H1 influenza hemagglutinin

Translational regulation of viral secretory proteins by the 5′ coding regions and a viral RNA-binding protein

(2017) Johan Nordholm et al.   JOURNAL OF CELL BIOLOGY

Alternative evolutionary histories in the sequence space of an ancient protein

(2017) Tyler N. Starr et al.   NATURE

Tackling influenza with broadly neutralizing antibodies

(2017) Davide Corti et al.   Current Opinion in Virology

Complete mapping of viral escape from neutralizing antibodies

(2017) Michael B. Doud et al.   PLoS Pathogens

Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses

(2016) M. Gordon Joyce et al.   CELL

Broadly neutralizing anti-influenza antibodies require Fc receptor engagement for in vivo protection

(2016) David J. DiLillo et al.   JOURNAL OF CLINICAL INVESTIGATION

Antibodies Against the Current Influenza A(H1N1) Vaccine Strain Do Not Protect Some Individuals From Infection With Contemporary Circulating Influenza A(H1N1) Virus Strains

(2016) Joshua G. Petrie et al.   JOURNAL OF INFECTIOUS DISEASES

Influenza Research Database: An integrated bioinformatics resource for influenza virus research

(2016) Yun Zhang et al.   NUCLEIC ACIDS RESEARCH

Prediction, dynamics, and visualization of antigenic phenotypes of seasonal influenza viruses

(2016) Richard A. Neher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Explaining the geographical origins of seasonal influenza A (H3N2)

(2016) Frank Wen et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Accurate Measurement of the Effects of All Amino-Acid Mutations on Influenza Hemagglutinin

(2016) Michael Doud et al.   Viruses-Basel

Two Escape Mechanisms of Influenza A Virus to a Broadly Neutralizing Stalk-Binding Antibody

(2016) Ning Chai et al.   PLoS Pathogens

Software for the analysis and visualization of deep mutational scanning data

(2015) Jesse D Bloom   BMC BIOINFORMATICS

Viral Receptor-Binding Site Antibodies with Diverse Germline Origins

(2015) Aaron G. Schmidt et al.   CELL

Preexisting human antibodies neutralize recently emerged H7N9 influenza strains

(2015) Carole J. Henry Dunand et al.   JOURNAL OF CLINICAL INVESTIGATION

Advances in the development of influenza virus vaccines

(2015) Florian Krammer et al.   NATURE REVIEWS DRUG DISCOVERY

Immune history profoundly affects broadly protective B cell responses to influenza

(2015) Sarah F. Andrews et al.   Science Translational Medicine

Identification of Hemagglutinin Residues Responsible for H3N2 Antigenic Drift during the 2014–2015 Influenza Season

(2015) Benjamin S. Chambers et al.   Cell Reports

Mutational Analysis of Measles Virus Suggests Constraints on Antigenic Variation of the Glycoproteins

(2015) Benjamin O. Fulton et al.   Cell Reports

Estimating the Life Course of Influenza A(H3N2) Antibody Responses from Cross-Sectional Data

(2015) Adam J. Kucharski et al.   PLOS BIOLOGY

Pathogen evolution and the immunological niche

(2014) Sarah Cobey   Annals of the New York Academy of Sciences

RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies

(2014) Alexandros Stamatakis   BIOINFORMATICS

An Experimentally Determined Evolutionary Model Dramatically Improves Phylogenetic Fit

(2014) Jesse D. Bloom   MOLECULAR BIOLOGY AND EVOLUTION

Historical contingency and its biophysical basis in glucocorticoid receptor evolution

(2014) Michael J. Harms et al.   NATURE

Broadly neutralizing hemagglutinin stalk–specific antibodies require FcγR interactions for protection against influenza virus in vivo

(2014) David J DiLillo et al.   NATURE MEDICINE

A Recommended Numbering Scheme for Influenza A HA Subtypes

(2014) David F. Burke et al.   PLoS One

Robustness against serum neutralization of a poliovirus type 1 from a lethal epidemic of poliomyelitis in the Republic of Congo in 2010

(2014) J. F. Drexler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of broadly cross-reactive antibody responses to the influenza HA stem region following H5N1 vaccination in humans

(2014) A. H. Ellebedy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The inherent mutational tolerance and antigenic evolvability of influenza hemagglutinin

(2014) Bargavi Thyagarajan et al.   eLife

Defining Influenza A Virus Hemagglutinin Antigenic Drift by Sequential Monoclonal Antibody Selection

(2013) Suman R. Das et al.   Cell Host & Microbe

Structure of a Classical Broadly Neutralizing Stem Antibody in Complex with a Pandemic H2 Influenza Virus Hemagglutinin

(2013) C. Dreyfus et al.   JOURNAL OF VIROLOGY

A Mutant Influenza Virus That Uses an N1 Neuraminidase as the Receptor-Binding Protein

(2013) Kathryn A. Hooper et al.   JOURNAL OF VIROLOGY

Broad protection against influenza infection by vectored immunoprophylaxis in mice

(2013) Alejandro B Balazs et al.   NATURE BIOTECHNOLOGY

Genome-wide mutagenesis of influenza virus reveals unique plasticity of the hemagglutinin and NS1 proteins

(2013) N. S. Heaton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A common solution to group 2 influenza virus neutralization

(2013) R. H. E. Friesen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Substitutions Near the Receptor Binding Site Determine Major Antigenic Change During Influenza Virus Evolution

(2013) B. F. Koel et al.   SCIENCE

Cross-neutralization of influenza A viruses mediated by a single antibody loop

(2012) Damian C. Ekiert et al.   NATURE

Heterosubtypic antibody recognition of the influenza virus hemagglutinin receptor binding site enhanced by avidity

(2012) P. S. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antigenic Drift in H5N1 Avian Influenza Virus in Poultry Is Driven by Mutations in Major Antigenic Sites of the Hemagglutinin Molecule Analogous to Those for Human Influenza Virus

(2011) G. Cattoli et al.   JOURNAL OF VIROLOGY

A Neutralizing Antibody Selected from Plasma Cells That Binds to Group 1 and Group 2 Influenza A Hemagglutinins

(2011) D. Corti et al.   SCIENCE

A Highly Conserved Neutralizing Epitope on Group 2 Influenza A Viruses

(2011) D. C. Ekiert et al.   SCIENCE

Modifications to the Hemagglutinin Cleavage Site Control the Virulence of a Neurotropic H1N1 Influenza Virus

(2010) X. Sun et al.   JOURNAL OF VIROLOGY

Permissive Secondary Mutations Enable the Evolution of Influenza Oseltamivir Resistance

(2010) J. D. Bloom et al.   SCIENCE

Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses

(2009) Jianhua Sui et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Antibody Recognition of a Highly Conserved Influenza Virus Epitope

(2009) D. C. Ekiert et al.   SCIENCE

Cross-Protective Potential of a Novel Monoclonal Antibody Directed against Antigenic Site B of the Hemagglutinin of Influenza A Viruses

(2009) Reiko Yoshida et al.   PLoS Pathogens

Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors

(2008) Xiaocong Yu et al.   NATURE

Heterosubtypic Neutralizing Monoclonal Antibodies Cross-Protective against H5N1 and H1N1 Recovered from Human IgM+ Memory B Cells

(2008) Mark Throsby et al.   PLoS One