Biomimetic artificial organelles with in vitro and in vivo activity triggered by reduction in microenvironment

PDMS- b -PMOXA polymersomes for hepatocyte targeting and assessment of toxicity

(2017) Klara Kiene et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Zebrafish as an early stage screening tool to study the systemic circulation of nanoparticulate drug delivery systems in vivo

(2017) Sandro Sieber et al.   JOURNAL OF CONTROLLED RELEASE

Biomimetic Strategy To Reversibly Trigger Functionality of Catalytic Nanocompartments by the Insertion of pH-Responsive Biovalves

(2017) Christoph Edlinger et al.   NANO LETTERS

Investigation of Horseradish Peroxidase Kinetics in an “Organelle-Like” Environment

(2017) Patric Baumann et al.   Small

Active surfaces engineered by immobilizing protein-polymer nanoreactors for selectively detecting sugar alcohols

(2016) Xiaoyan Zhang et al.   BIOMATERIALS

Bioinspired polymer vesicles and membranes for biological and medical applications

(2016) Cornelia G. Palivan et al.   CHEMICAL SOCIETY REVIEWS

Enzymatic reactions in confined environments

(2016) Andreas Küchler et al.   Nature Nanotechnology

A biomimetic DNA-based channel for the ligand-controlled transport of charged molecular cargo across a biological membrane

(2016) Jonathan R. Burns et al.   Nature Nanotechnology

The nanotechnology of life-inspired systems

(2016) Bartosz A. Grzybowski et al.   Nature Nanotechnology

A redox state-dictated signalling pathway deciphers the malignant cell specificity of CD40-mediated apoptosis

(2016) C J Dunnill et al.   ONCOGENE

Bioactive cell-like hybrids coassembled from (glyco)dendrimersomes with bacterial membranes

(2016) Qi Xiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nonenzymatic biomimetic remodeling of phospholipids in synthetic liposomes

(2016) Roberto J. Brea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Subcompartmentalized Nanoreactors as Artificial Organelle with Intracellular Activity

(2016) Bo Thingholm et al.   Small

Biomimetic Solid-State Nanochannels: From Fundamental Research to Practical Applications

(2016) Kai Xiao et al.   Small

Neuronal differentiation is associated with a redox-regulated increase of copper flow to the secretory pathway

(2016) Yuta Hatori et al.   Nature Communications

Small Subcompartmentalized Microreactors as Support for Hepatocytes

(2016) Yan Zhang et al.   Advanced Healthcare Materials

Intracellular Microreactors as Artificial Organelles to Conduct Multiple Enzymatic Reactions Simultaneously

(2016) María Godoy-Gallardo et al.   Advanced Healthcare Materials

Polymersomes with engineered ion selective permeability as stimuli-responsive nanocompartments with preserved architecture

(2015) Mihai Lomora et al.   BIOMATERIALS

Dynamics of Membrane Proteins within Synthetic Polymer Membranes with Large Hydrophobic Mismatch

(2015) Fabian Itel et al.   NANO LETTERS

Stimuli-Triggered Activity of Nanoreactors by Biomimetic Engineering Polymer Membranes

(2015) Tomaž Einfalt et al.   NANO LETTERS

Zebrafish as tools for drug discovery

(2015) Calum A. MacRae et al.   NATURE REVIEWS DRUG DISCOVERY

Polymeric 3D nano-architectures for transport and delivery of therapeutically relevant biomacromolecules

(2015) G. Gunkel-Grabole et al.   Biomaterials Science

Nanoparticles as Drug Delivery System against Tuberculosis in Zebrafish Embryos: Direct Visualization and Treatment

(2014) Federico Fenaroli et al.   ACS Nano

Nanomimics of Host Cell Membranes Block Invasion and Expose Invasive Malaria Parasites

(2014) Adrian Najer et al.   ACS Nano

Macrophage-pathogen interactions in infectious diseases: new therapeutic insights from the zebrafish host model

(2014) V. Torraca et al.   Disease Models & Mechanisms

Polymersomes conjugated to 83-14 monoclonal antibodies: Invitro targeting of brain capillary endothelial cells

(2014) Le-Ha Dieu et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Molecular Organization and Dynamics in Polymersome Membranes: A Lateral Diffusion Study

(2014) Fabian Itel et al.   MACROMOLECULES

Effect of Molecular Parameters on the Architecture and Membrane Properties of 3D Assemblies of Amphiphilic Copolymers

(2014) Dalin Wu et al.   MACROMOLECULES

An intercompartmental enzymatic cascade reaction in channel-equipped polymersome-in-polymersome architectures

(2014) Winna Siti et al.   Journal of Materials Chemistry B

Cascade Reactions in Multicompartmentalized Polymersomes

(2013) Ruud J. R. W. Peters et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reduction-Responsive Polymeric Micelles and Vesicles for Triggered Intracellular Drug Release

(2013) Huanli Sun et al.   ANTIOXIDANTS & REDOX SIGNALING

Aiding Nature’s Organelles: Artificial Peroxisomes Play Their Role

(2013) Pascal Tanner et al.   NANO LETTERS

Glutathione peroxidase activity is neuroprotective in models of Huntington's disease

(2013) Robert P Mason et al.   NATURE GENETICS

In vivo nanotoxicity testing using the zebrafish embryo assay

(2013) Larissa Y. Rizzo et al.   Journal of Materials Chemistry B

Redox regulation of mitochondrial function with emphasis on cysteine oxidation reactions

(2013) Ryan J. Mailloux et al.   Redox Biology

Towards an artificial cell

(2012) Daniel A. Hammer et al.   FEBS LETTERS

High-Density Reconstitution of Functional Water Channels into Vesicular and Planar Block Copolymer Membranes

(2012) Manish Kumar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Light-responsive polymer nanoreactors: a source of reactive oxygen species on demand

(2012) Patric Baumann et al.   Nanoscale

Synthetic nanoparticles functionalized with biomimetic leukocyte membranes possess cell-like functions

(2012) Alessandro Parodi et al.   Nature Nanotechnology

Differential Uptake of Functionalized Polystyrene Nanoparticles by Human Macrophages and a Monocytic Cell Line

(2011) Oleg Lunov et al.   ACS Nano

Zebrafish embryos and larvae: A new generation of disease models and drug screens

(2011) Shaukat Ali et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Protein–polymer nanoreactors for medical applications

(2011) Cornelia G. Palivan et al.   CHEMICAL SOCIETY REVIEWS

Designs for life: protocell models in the laboratory

(2011) Alicja J. Dzieciol et al.   CHEMICAL SOCIETY REVIEWS

Bio-inspired, bioengineered and biomimetic drug delivery carriers

(2011) Jin-Wook Yoo et al.   NATURE REVIEWS DRUG DISCOVERY

Engineering of the E. coli Outer Membrane Protein FhuA to overcome the Hydrophobic Mismatch in Thick Polymeric Membranes

(2011) Noor Muhammad et al.   JOURNAL OF NANOBIOTECHNOLOGY

Reactive oxygen species, cellular redox systems, and apoptosis

(2010) Magdalena L. Circu et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Identification of Markers of Macrophage Differentiation in PMA-Stimulated THP-1 Cells and Monocyte-Derived Macrophages

(2010) Marc Daigneault et al.   PLoS One

Functionalized Nanocompartments (Synthosomes) with a Reduction-Triggered Release System

(2008) Ozana Onaca et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis, characterization and chondroprotective properties of a hyaluronan thioethyl ether derivative

(2008) Monica A. Serban et al.   BIOMATERIALS