Over-elongation of centrioles in cancer promotes centriole amplification and chromosome missegregation

Asymmetric Centriole Numbers at Spindle Poles Cause Chromosome Missegregation in Cancer

(2017) Marco R. Cosenza et al.   Cell Reports

Genomic analyses identify molecular subtypes of pancreatic cancer

(2016) Peter Bailey et al.   NATURE

MDM1 is a microtubule-binding protein that negatively regulates centriole duplication

(2015) Daniel Van de Mark et al.   MOLECULAR BIOLOGY OF THE CELL

Chromothripsis from DNA damage in micronuclei

(2015) Cheng-Zhong Zhang et al.   NATURE

Reversible centriole depletion with an inhibitor of Polo-like kinase 4

(2015) Y. L. Wong et al.   SCIENCE

Functional Characterization of CFI-400945, a Polo-like Kinase 4 Inhibitor, as a Potential Anticancer Agent

(2014) Jacqueline M. Mason et al.   CANCER CELL

Analysis of TP53 Mutation Status in Human Cancer Cell Lines: A Reassessment

(2014) Bernard Leroy et al.   HUMAN MUTATION

Oncogene-like induction of cellular invasion from centrosome amplification

(2014) Susana A. Godinho et al.   NATURE

Causes and consequences of centrosome abnormalities in cancer

(2014) S. A. Godinho et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Centrosome aberrations in bone marrow cells from patients with myelodysplastic syndromes correlate with chromosomal instability

(2013) Florian Nolte et al.   ANNALS OF HEMATOLOGY

Design, Synthesis, and Biological Evaluation of an Allosteric Inhibitor of HSET that Targets Cancer Cells with Supernumerary Centrosomes

(2013) Ciorsdaidh A. Watts et al.   CHEMISTRY & BIOLOGY

Discovering Regulators of Centriole Biogenesis through siRNA-Based Functional Genomics in Human Cells

(2013) Fernando R. Balestra et al.   DEVELOPMENTAL CELL

CEP120 interacts with CPAP and positively regulates centriole elongation

(2013) Yi-Nan Lin et al.   JOURNAL OF CELL BIOLOGY

Centrosome amplification causes microcephaly

(2013) Véronique Marthiens et al.   NATURE CELL BIOLOGY

Microsatellite instability has a positive prognostic impact on stage II colorectal cancer after complete resection: results from a large, consecutive Norwegian series

(2012) M. A. Merok et al.   ANNALS OF ONCOLOGY

Klp10A, a Microtubule-Depolymerizing Kinesin-13, Cooperates with CP110 to Control Drosophila Centriole Length

(2012) Nathalie Delgehyr et al.   CURRENT BIOLOGY

The autoregulated instability of Polo-like kinase 4 limits centrosome duplication to once per cell cycle

(2012) A. J. Holland et al.   GENES & DEVELOPMENT

A Clinical Overview of Centrosome Amplification in Human Cancers

(2012) Jason Yongsheng Chan   International Journal of Biological Sciences

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

A telomere-dependent DNA damage checkpoint induced by prolonged mitotic arrest

(2012) Makoto T Hayashi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Centrosome amplification as a putative prognostic biomarker for the classification of urothelial carcinomas

(2011) Yoshiaki Yamamoto et al.   HUMAN PATHOLOGY

mRNA and microRNA Expression Profiles of the NCI-60 Integrated with Drug Activities

(2010) H. Liu et al.   MOLECULAR CANCER THERAPEUTICS

Minireview: Basal-Like Breast Cancer: From Molecular Profiles to Targeted Therapies

(2010) Daniel J. Toft et al.   MOLECULAR ENDOCRINOLOGY

Overly Long Centrioles and Defective Cell Division upon Excess of the SAS-4-Related Protein CPAP

(2009) Gregor Kohlmaier et al.   CURRENT BIOLOGY

Asymmetric centrosome inheritance maintains neural progenitors in the neocortex

(2009) Xiaoqun Wang et al.   NATURE

A mechanism linking extra centrosomes to chromosomal instability

(2009) Neil J. Ganem et al.   NATURE

Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

(2009) Andrew J. Holland et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Multipolar Spindle Pole Coalescence Is a Major Source of Kinetochore Mis-Attachment and Chromosome Mis-Segregation in Cancer Cells

(2009) William T. Silkworth et al.   PLoS One

Centrosome function in cancer: guilty or innocent?

(2009) Deborah Zyss et al.   TRENDS IN CELL BIOLOGY

Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes

(2008) M. Kwon et al.   GENES & DEVELOPMENT

Characterization of chromosomes and chromosomal fragments in human lymphocyte micronuclei by telomeric and centromeric FISH

(2008) H. K. Lindberg et al.   MUTAGENESIS

Control of daughter centriole formation by the pericentriolar material

(2008) Jadranka Loncarek et al.   NATURE CELL BIOLOGY