Dissection and function of autoimmunity-associated TNFAIP3 (A20) gene enhancers in humanized mouse models
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Dissection and function of autoimmunity-associated TNFAIP3 (A20) gene enhancers in humanized mouse models
Authors
Keywords
-
Journal
Nature Communications
Volume 9, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-02-08
DOI
10.1038/s41467-018-03081-7
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF
- (2017) Kyuho Kang et al. IMMUNITY
- Comparative transcriptomics in human and mouse
- (2017) Alessandra Breschi et al. NATURE REVIEWS GENETICS
- Ever-Changing Landscapes: Transcriptional Enhancers in Development and Evolution
- (2016) Hannah K. Long et al. CELL
- Deleting an Nr4a1 Super-Enhancer Subdomain Ablates Ly6C low Monocytes while Preserving Macrophage Gene Function
- (2016) Graham D. Thomas et al. IMMUNITY
- Hierarchy within the mammary STAT5-driven Wap super-enhancer
- (2016) Ha Youn Shin et al. NATURE GENETICS
- Genetic dissection of the α-globin super-enhancer in vivo
- (2016) Deborah Hay et al. NATURE GENETICS
- Role of non-coding sequence variants in cancer
- (2016) Ekta Khurana et al. NATURE REVIEWS GENETICS
- High-resolution interrogation of functional elements in the noncoding genome
- (2016) N. E. Sanjana et al. SCIENCE
- Systematic mapping of functional enhancer–promoter connections with CRISPR interference
- (2016) Charles P. Fulco et al. SCIENCE
- Genetic Control of Chromatin States in Humans Involves Local and Distal Chromosomal Interactions
- (2015) Fabian Grubert et al. CELL
- Enhancer Evolution across 20 Mammalian Species
- (2015) Diego Villar et al. CELL
- Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions
- (2015) Darío G. Lupiáñez et al. CELL
- BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis
- (2015) Matthew C. Canver et al. NATURE
- Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease
- (2015) Qing Zhou et al. NATURE GENETICS
- The deubiquitinase A20 in immunopathology of autoimmune diseases
- (2014) Ishani Majumdar et al. AUTOIMMUNITY
- A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
- (2014) Suhas S.P. Rao et al. CELL
- Control of Cell Identity Genes Occurs in Insulated Neighborhoods in Mammalian Chromosomes
- (2014) Jill M. Dowen et al. CELL
- Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis
- (2014) Lieselotte Vande Walle et al. NATURE
- Genetic and epigenetic fine mapping of causal autoimmune disease variants
- (2014) Kyle Kai-How Farh et al. NATURE
- Chemokine (C–X–C motif) ligand (CXCL)10 in autoimmune diseases
- (2013) Alessandro Antonelli et al. AUTOIMMUNITY REVIEWS
- CRISPR/Cas9-Targeted Mutagenesis in Caenorhabditis elegans
- (2013) Selma Waaijers et al. GENETICS
- Synergistic Activation of Inflammatory Cytokine Genes by Interferon-γ-Induced Chromatin Remodeling and Toll-like Receptor Signaling
- (2013) Yu Qiao et al. IMMUNITY
- A20 in inflammation and autoimmunity
- (2013) Leen Catrysse et al. TRENDS IN IMMUNOLOGY
- Characterisation of fibroblast-like synoviocytes from a murine model of joint inflammation
- (2013) Rowan S Hardy et al. ARTHRITIS RESEARCH & THERAPY
- An Enhancer Element Harboring Variants Associated with Systemic Lupus Erythematosus Engages the TNFAIP3 Promoter to Influence A20 Expression
- (2013) Shaofeng Wang et al. PLoS Genetics
- Using formaldehyde-assisted isolation of regulatory elements (FAIRE) to isolate active regulatory DNA
- (2012) Jeremy M Simon et al. Nature Protocols
- Systematic Localization of Common Disease-Associated Variation in Regulatory DNA
- (2012) M. T. Maurano et al. SCIENCE
- The Ubiquitin-Editing Protein A20 Prevents Dendritic Cell Activation, Recognition of Apoptotic Cells, and Systemic Autoimmunity
- (2011) Mirjam Kool et al. IMMUNITY
- A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis
- (2011) Mourad Matmati et al. NATURE GENETICS
- Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus
- (2011) Indra Adrianto et al. NATURE GENETICS
- Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis
- (2011) Gianna Elena Hammer et al. NATURE IMMUNOLOGY
- Genomically humanized mice: technologies and promises
- (2011) Anny Devoy et al. NATURE REVIEWS GENETICS
- Expression, biological activities and mechanisms of action of A20 (TNFAIP3)
- (2010) Lynn Verstrepen et al. BIOCHEMICAL PHARMACOLOGY
- B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice
- (2010) Y. Chu et al. BLOOD
- A20 deficiency in B cells enhances B-cell proliferation and results in the development of autoantibodies
- (2010) Nadine Hövelmeyer et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The Ubiquitin Modifying Enzyme A20 Restricts B Cell Survival and Prevents Autoimmunity
- (2010) Rita M. Tavares et al. IMMUNITY
- Rapid bacterial artificial chromosome modification for large-scale mouse transgenesis
- (2010) Shiaoching Gong et al. Nature Protocols
- CXCL10 and autoimmune diseases
- (2008) Eun Young Lee et al. AUTOIMMUNITY REVIEWS
- Integrated Regulation of Toll-like Receptor Responses by Notch and Interferon-γ Pathways
- (2008) Xiaoyu Hu et al. IMMUNITY
- Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus
- (2008) Robert R Graham et al. NATURE GENETICS
- Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus
- (2008) Stacy L Musone et al. NATURE GENETICS
- Species-Specific Transcription in Mice Carrying Human Chromosome 21
- (2008) M. D. Wilson et al. SCIENCE
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started