Regulation of chitinase-3-like-1 in T cell elicits Th1 and cytotoxic responses to inhibit lung metastasis

Fibroblasts drive an immunosuppressive and growth-promoting microenvironment in breast cancer via secretion of Chitinase 3-like 1

(2017) N Cohen et al.   ONCOGENE

CHI3L1 nuclear localization in monocyte derived dendritic cells

(2016) Michelino Di Rosa et al.   IMMUNOBIOLOGY

Cell Type Preference of a Novel Human Derived Cell-Permeable Peptide dNP2 and TAT in Murine Splenic Immune Cells

(2016) Sangho Lim et al.   PLoS One

Use of Cell-Penetrating Peptides in Dendritic Cell-Based Vaccination

(2016) Sangho Lim et al.   Immune Network

Chitinase 3–like-1 Regulates Both Visceral Fat Accumulation and Asthma-like Th2 Inflammation

(2015) Farida Ahangari et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Role of Chitinase 3–Like-1 in Interleukin-18–Induced Pulmonary Type 1, Type 2, and Type 17 Inflammation; Alveolar Destruction; and Airway Fibrosis in the Murine Lung

(2015) Min-Jong Kang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

CCL5-Mediated Th2 Immune Polarization Promotes Metastasis in Luminal Breast Cancer

(2015) Q. Zhang et al.   CANCER RESEARCH

Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer

(2015) Christina Twyman-Saint Victor et al.   NATURE

The receptor NLRP3 is a transcriptional regulator of TH2 differentiation

(2015) Mélanie Bruchard et al.   NATURE IMMUNOLOGY

Role of Chitinase 3-like-1 and Semaphorin 7a in Pulmonary Melanoma Metastasis

(2014) B. Ma et al.   CANCER RESEARCH

Chitinase 3 like 1 is associated with tumor angiogenesis in cervical cancer

(2014) Nipaporn Ngernyuang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

YKL-40 as a Novel Factor Associated with Inflammation and Catabolic Mechanisms in Osteoarthritic Joints

(2014) Tuija Väänänen et al.   MEDIATORS OF INFLAMMATION

Cell membrane penetrating function of the nuclear localization sequence in human cytokine IL-1α

(2014) Ja-Hyun Koo et al.   MOLECULAR BIOLOGY REPORTS

Chitinase-like proteins promote IL-17-mediated neutrophilia in a tradeoff between nematode killing and host damage

(2014) Tara E Sutherland et al.   NATURE IMMUNOLOGY

Efficacy and Toxicity Management of 19-28z CAR T Cell Therapy in B Cell Acute Lymphoblastic Leukemia

(2014) M. L. Davila et al.   Science Translational Medicine

Ym1, an eosinophilic chemotactic factor, participates in the brain inflammation induced by Angiostrongylus cantonensis in mice

(2013) Jia Zhao et al.   PARASITOLOGY RESEARCH

Chitinase 3-like 1 Regulates Cellular and Tissue Responses via IL-13 Receptor α2

(2013) Chuan Hua He et al.   Cell Reports

Breast regression protein-39 (BRP-39) promotes dendritic cell maturation in vitro and enhances Th2 inflammation in murine model of asthma

(2012) Qian Xu et al.   ACTA PHARMACOLOGICA SINICA

IL-18 Induces Emphysema and Airway and Vascular Remodeling via IFN-γ, IL-17A, and IL-13

(2012) Min-Jong Kang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Adoptive transfer of IL-4Rα+ macrophages is sufficient to enhance eosinophilic inflammation in a mouse model of allergic lung inflammation

(2012) Andrew Q Ford et al.   BMC IMMUNOLOGY

Chitinase 3-like-1 Promotes Streptococcus pneumoniae Killing and Augments Host Tolerance to Lung Antibacterial Responses

(2012) Charles S. Dela Cruz et al.   Cell Host & Microbe

Twist1 Regulates Ifng Expression in Th1 Cells by Interfering with Runx3 Function

(2012) D. Pham et al.   JOURNAL OF IMMUNOLOGY

Identification of a novel cell-penetrating peptide from human phosphatidate phosphatase LPIN3

(2012) Sangho Lim et al.   MOLECULES AND CELLS

Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival

(2012) Steffen Walter et al.   NATURE MEDICINE

Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

(2012) Suzanne L. Topalian et al.   NEW ENGLAND JOURNAL OF MEDICINE

Characterization of a chitinase with antifungal activity from a native Serratia marcescens B4A

(2011) Mandana Zarei et al.   BRAZILIAN JOURNAL OF MICROBIOLOGY

Chitinase 3-like 1 promotes macrophage recruitment and angiogenesis in colorectal cancer

(2011) M Kawada et al.   ONCOGENE

CHI3L1 (YKL-40) is expressed in human gliomas and regulates the invasion, growth and survival of glioma cells

(2010) Bo Mi Ku et al.   INTERNATIONAL JOURNAL OF CANCER

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

(2010) F. Stephen Hodi et al.   NEW ENGLAND JOURNAL OF MEDICINE

PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors

(2010) M. A. Curran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs

(2009) Fernando Cruz-Guilloty et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13–induced tissue responses and apoptosis

(2009) Chun Geun Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Ym1/2 Promotes Th2 Cytokine Expression by Inhibiting 12/15(S)-Lipoxygenase: Identification of a Novel Pathway for Regulating Allergic Inflammation

(2009) Y. Cai et al.   JOURNAL OF IMMUNOLOGY

YKL-40, a secreted glycoprotein, promotes tumor angiogenesis

(2009) R Shao et al.   ONCOGENE

Autoregulation of Th1-mediated inflammation bytwist1

(2008) Uwe Niesner et al.   JOURNAL OF EXPERIMENTAL MEDICINE