Structural basis for the regulation of human 5,10-methylenetetrahydrofolate reductase by phosphorylation and S-adenosylmethionine inhibition

SAMTOR is anS-adenosylmethionine sensor for the mTORC1 pathway

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Mutation Update and Review of Severe Methylenetetrahydrofolate Reductase Deficiency

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Functional characterization of missense mutations in severe methylenetetrahydrofolate reductase deficiency using a human expression system

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Dali server update

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Structural elucidation of the NADP(H) phosphatase activity of staphylococcal dual-specific IMPase/NADP(H) phosphatase

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Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism: Epidemiology, metabolism and the associated diseases

(2015) Siaw-Cheok Liew et al.   European Journal of Medical Genetics

Insights into Severe 5,10-Methylenetetrahydrofolate Reductase Deficiency: Molecular Genetic and Enzymatic Characterization of 76 Patients

(2015) Patricie Burda et al.   HUMAN MUTATION

MTHFR promotes heterochromatin maintenance

(2014) Bingtao Zhu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inter-domain Communication of Human Cystathionine β-Synthase

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Impact of Quaternary Structure Dynamics on Allosteric Drug Discovery

(2013) Eileen K. Jaffe   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Structural and functional studies of S-adenosyl-L-methionine binding proteins: a ligand-centric approach

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New developments in theATSASprogram package for small-angle scattering data analysis

(2012) Maxim V. Petoukhov et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Sinefungin Derivatives as Inhibitors and Structure Probes of Protein Lysine Methyltransferase SETD2

(2012) Weihong Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Charge-Surface Correlation in Electrospray Ionization of Folded and Unfolded Proteins

(2011) Lorenzo Testa et al.   ANALYTICAL CHEMISTRY

Comprehensive Analysis of Protein Modifications by Top-Down Mass Spectrometry

(2011) Han Zhang et al.   Circulation-Cardiovascular Genetics

Properties and Crystal Structure of Methylenetetrahydrofolate Reductase from Thermus thermophilus HB8

(2011) Sayaka Igari et al.   PLoS One

Features and development ofCoot

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

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ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids

(2010) H. Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

Functional Role for the Conformationally Mobile Phenylalanine 223 in the Reaction of Methylenetetrahydrofolate Reductase fromEscherichia coli

(2009) Moon N. Lee et al.   BIOCHEMISTRY

Knock-down of methylenetetrahydrofolate reductase reduces gastric cancer cell survival: An in vitro study

(2008) D SUN et al.   CELL BIOLOGY INTERNATIONAL

Methylenetetrahydrofolate Reductase (MTHFR): A Novel Target for Cancer Therapy

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Riboswitches that Sense S-adenosylhomocysteine and Activate Genes Involved in Coenzyme Recycling

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The prevalence of folate-remedial MTHFR enzyme variants in humans

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