Structural basis for the regulation of human 5,10-methylenetetrahydrofolate reductase by phosphorylation and S-adenosylmethionine inhibition
出版年份 2018 全文链接
标题
Structural basis for the regulation of human 5,10-methylenetetrahydrofolate reductase by phosphorylation and S-adenosylmethionine inhibition
作者
关键词
-
出版物
Nature Communications
Volume 9, Issue 1, Pages -
出版商
Springer Nature
发表日期
2018-06-05
DOI
10.1038/s41467-018-04735-2
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- SAMTOR is anS-adenosylmethionine sensor for the mTORC1 pathway
- (2017) Xin Gu et al. SCIENCE
- Mutation Update and Review of Severe Methylenetetrahydrofolate Reductase Deficiency
- (2016) D. Sean Froese et al. HUMAN MUTATION
- Functional characterization of missense mutations in severe methylenetetrahydrofolate reductase deficiency using a human expression system
- (2016) Patricie Burda et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Dali server update
- (2016) Liisa Holm et al. NUCLEIC ACIDS RESEARCH
- Structural elucidation of the NADP(H) phosphatase activity of staphylococcal dual-specific IMPase/NADP(H) phosphatase
- (2016) Sudipta Bhattacharyya et al. Acta Crystallographica Section D-Structural Biology
- Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism: Epidemiology, metabolism and the associated diseases
- (2015) Siaw-Cheok Liew et al. European Journal of Medical Genetics
- Insights into Severe 5,10-Methylenetetrahydrofolate Reductase Deficiency: Molecular Genetic and Enzymatic Characterization of 76 Patients
- (2015) Patricie Burda et al. HUMAN MUTATION
- MTHFR promotes heterochromatin maintenance
- (2014) Bingtao Zhu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Inter-domain Communication of Human Cystathionine β-Synthase
- (2014) Thomas J. McCorvie et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Decision making inxia2
- (2013) Graeme Winter et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Impact of Quaternary Structure Dynamics on Allosteric Drug Discovery
- (2013) Eileen K. Jaffe CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Structural and functional studies of S-adenosyl-L-methionine binding proteins: a ligand-centric approach
- (2013) Rajaram Gana et al. BMC STRUCTURAL BIOLOGY
- New developments in theATSASprogram package for small-angle scattering data analysis
- (2012) Maxim V. Petoukhov et al. JOURNAL OF APPLIED CRYSTALLOGRAPHY
- Sinefungin Derivatives as Inhibitors and Structure Probes of Protein Lysine Methyltransferase SETD2
- (2012) Weihong Zheng et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Charge-Surface Correlation in Electrospray Ionization of Folded and Unfolded Proteins
- (2011) Lorenzo Testa et al. ANALYTICAL CHEMISTRY
- Comprehensive Analysis of Protein Modifications by Top-Down Mass Spectrometry
- (2011) Han Zhang et al. Circulation-Cardiovascular Genetics
- Properties and Crystal Structure of Methylenetetrahydrofolate Reductase from Thermus thermophilus HB8
- (2011) Sayaka Igari et al. PLoS One
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids
- (2010) H. Ashkenazy et al. NUCLEIC ACIDS RESEARCH
- Functional Role for the Conformationally Mobile Phenylalanine 223 in the Reaction of Methylenetetrahydrofolate Reductase fromEscherichia coli
- (2009) Moon N. Lee et al. BIOCHEMISTRY
- Knock-down of methylenetetrahydrofolate reductase reduces gastric cancer cell survival: An in vitro study
- (2008) D SUN et al. CELL BIOLOGY INTERNATIONAL
- Methylenetetrahydrofolate Reductase (MTHFR): A Novel Target for Cancer Therapy
- (2008) J. Stankova et al. CURRENT PHARMACEUTICAL DESIGN
- Riboswitches that Sense S-adenosylhomocysteine and Activate Genes Involved in Coenzyme Recycling
- (2008) Joy Xin Wang et al. MOLECULAR CELL
- The prevalence of folate-remedial MTHFR enzyme variants in humans
- (2008) N. J. Marini et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started