Structure-guided design of an Hsp90β N-terminal isoform-selective inhibitor
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Structure-guided design of an Hsp90β N-terminal isoform-selective inhibitor
Authors
Keywords
-
Journal
Nature Communications
Volume 9, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-01-24
DOI
10.1038/s41467-017-02013-1
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Selective Targeting of the KRAS G12C Mutant: Kicking KRAS When It’s Down
- (2016) G. Aaron Hobbs et al. CANCER CELL
- Paralog Specific Hsp90 Inhibitors - A Brief History and a Bright Future
- (2016) Daniel T. Gewirth CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Development of Glucose Regulated Protein 94-Selective Inhibitors Based on the BnIm and Radamide Scaffold
- (2016) Vincent M. Crowley et al. JOURNAL OF MEDICINAL CHEMISTRY
- Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1
- (2015) Changwook Lee et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Natural Product Inspired N-Terminal Hsp90 Inhibitors: From Bench to Bedside?
- (2015) Anuj Khandelwal et al. MEDICINAL RESEARCH REVIEWS
- Maximizing the Therapeutic Potential of HSP90 Inhibitors
- (2015) L. M. Butler et al. MOLECULAR CANCER RESEARCH
- Hsp90 interaction with clients
- (2015) G. Elif Karagöz et al. TRENDS IN BIOCHEMICAL SCIENCES
- Client Proteins and Small Molecule Inhibitors Display Distinct Binding Preferences for Constitutive and Stress-Induced HSP90 Isoforms and Their Conformationally Restricted Mutants
- (2015) Thomas L. Prince et al. PLoS One
- Progress in the Discovery and Development of Heat Shock Protein 90 (Hsp90) Inhibitors
- (2014) Rohit Bhat et al. JOURNAL OF MEDICINAL CHEMISTRY
- Stressing the Development of Small Molecules Targeting HSP90
- (2013) L. Neckers et al. CLINICAL CANCER RESEARCH
- Hsp90, an unlikely ally in the war on cancer
- (2013) Jared J. Barrott et al. FEBS Journal
- Inhibition of HSP90 molecular chaperones: moving into the clinic
- (2013) Rocio Garcia-Carbonero et al. LANCET ONCOLOGY
- Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2
- (2013) Pallav D Patel et al. Nature Chemical Biology
- A global view of Hsp90 functions
- (2013) Gabriela Chiosis et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The chaperone Hsp90: changing partners for demanding clients
- (2013) Alina Röhl et al. TRENDS IN BIOCHEMICAL SCIENCES
- Targeting the molecular chaperone heat shock protein 90 (HSP90): Lessons learned and future directions
- (2012) David S. Hong et al. CANCER TREATMENT REVIEWS
- Hsp90 Molecular Chaperone Inhibitors: Are We There Yet?
- (2012) L. Neckers et al. CLINICAL CANCER RESEARCH
- The Therapeutic Target Hsp90 and Cancer Hallmarks
- (2012) Yoshihiko Miyata et al. CURRENT PHARMACEUTICAL DESIGN
- Development of a Grp94 inhibitor
- (2012) Adam S. Duerfeldt et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The hERG Channel Is Dependent upon the Hsp90α Isoform for Maturation and Trafficking
- (2012) Laura B. Peterson et al. MOLECULAR PHARMACEUTICS
- Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers
- (2011) Komal Jhaveri et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- HSP90 inhibition: two-pronged exploitation of cancer dependencies
- (2011) Jon Travers et al. DRUG DISCOVERY TODAY
- Thermodynamics of radicicol binding to human Hsp90 alpha and beta isoforms
- (2010) Asta Zubrienė et al. BIOPHYSICAL CHEMISTRY
- Discovery of (2,4-Dihydroxy-5-isopropylphenyl)-[5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl]methanone (AT13387), a Novel Inhibitor of the Molecular Chaperone Hsp90 by Fragment Based Drug Design
- (2010) Andrew J. Woodhead et al. JOURNAL OF MEDICINAL CHEMISTRY
- Fragment-Based Drug Discovery Applied to Hsp90. Discovery of Two Lead Series with High Ligand Efficiency
- (2010) Christopher W. Murray et al. JOURNAL OF MEDICINAL CHEMISTRY
- Understanding of the Hsp90 molecular chaperone reaches new heights
- (2010) Cara K Vaughan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Hsp90 and co-chaperones twist the functions of diverse client proteins
- (2009) Abbey Zuehlke et al. BIOPOLYMERS
- Heat Shock Protein 90: Inhibitors in Clinical Trials
- (2009) Marco A. Biamonte et al. JOURNAL OF MEDICINAL CHEMISTRY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started