Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer

Tensins are versatile regulators of Rho GTPase signalling and cell adhesion

(2016) Anne Blangy   BIOLOGY OF THE CELL

Cancer statistics, 2016

(2016) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Condensin-Based Chromosome Organization from Bacteria to Vertebrates

(2016) Tatsuya Hirano   CELL

Fox transcription factors: from development to disease

(2016) Maria L. Golson et al.   DEVELOPMENT

The role of hepatocyte nuclear factor 1β in disease and development

(2016) R. El-Khairi et al.   DIABETES OBESITY & METABOLISM

Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21

(2016)   Oncotarget

Glucose Tolerance Is Improved in Mice Invalidated for the Nuclear Receptor HNF-4γ: A Critical Role for Enteroendocrine Cell Lineage

(2015) Floriane Baraille et al.   DIABETES

Epidemiology and Inherited Predisposition for Sporadic Pancreatic Adenocarcinoma

(2015) Rachael Z. Stolzenberg-Solomon et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Two new loci and gene sets related to sex determination and cancer progression are associated with susceptibility to testicular germ cell tumor

(2015) W. Kristiansen et al.   HUMAN MOLECULAR GENETICS

TERTgene harbors multiple variants associated with pancreatic cancer susceptibility

(2015) Daniele Campa et al.   INTERNATIONAL JOURNAL OF CANCER

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer

(2015) Erica J Childs et al.   NATURE GENETICS

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

(2015) Jimmy Z Liu et al.   NATURE GENETICS

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

Hepatocyte Nuclear Factor 1A (HNF1A) as a Possible Tumor Suppressor in Pancreatic Cancer

(2015) Zhaofan Luo et al.   PLoS One

European cancer mortality predictions for the year 2014

(2014) M. Malvezzi et al.   ANNALS OF ONCOLOGY

Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States

(2014) L. Rahib et al.   CANCER RESEARCH

Transcriptome analysis of pancreatic cancer reveals a tumor suppressor function for HNF1A

(2014) Jason W. Hoskins et al.   CARCINOGENESIS

Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk

(2014) Jodie N. Painter et al.   HUMAN MOLECULAR GENETICS

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33

(2014) Z. Wang et al.   HUMAN MOLECULAR GENETICS

Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer

(2014) Brian M Wolpin et al.   NATURE GENETICS

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

(2014) Anubha Mahajan et al.   NATURE GENETICS

Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development

(2014) Jared R Mayers et al.   NATURE MEDICINE

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

(2013) Sonja I Berndt et al.   NATURE GENETICS

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

(2013) Kyriaki Michailidou et al.   NATURE GENETICS

Molecular Profiling of Multiple Human Cancers Defines an Inflammatory Cancer-Associated Molecular Pattern and Uncovers KPNA2 as a Uniform Poor Prognostic Cancer Marker

(2013) Saleh M. Rachidi et al.   PLoS One

Matrix eQTL: ultra fast eQTL analysis via large matrix operations

(2012) A. A. Shabalin   BIOINFORMATICS

Lack of Replication of Seven Pancreatic Cancer Susceptibility Loci Identified in Two Asian Populations

(2012) D. Campa et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

(2012) Anna Köttgen et al.   NATURE GENETICS

GeneCodis3: a non-redundant and modular enrichment analysis tool for functional genomics

(2012) D. Tabas-Madrid et al.   NUCLEIC ACIDS RESEARCH

MODY

(2011) Stefan S. Fajans et al.   DIABETES CARE

Gene expression dynamics after murine pancreatitis unveils novel roles for Hnf1α in acinar cell homeostasis

(2011) Xavier Molero et al.   GUT

Large-scale fine mapping of the HNF1B locus and prostate cancer risk

(2011) Sonja I. Berndt et al.   HUMAN MOLECULAR GENETICS

Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations

(2011) Chen Wu et al.   NATURE GENETICS

Transcription factor binding predictions using TRAP for the analysis of ChIP-seq data and regulatory SNPs

(2011) Morgane Thomas-Chollier et al.   Nature Protocols

ATM Mutations in Patients with Hereditary Pancreatic Cancer

(2011) Nicholas J. Roberts et al.   Cancer Discovery

Aurora B Interacts with NIR-p53, Leading to p53 Phosphorylation in Its DNA-binding Domain and Subsequent Functional Suppression

(2010) Liming Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33

(2010) Gloria M Petersen et al.   NATURE GENETICS

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

(2010) Elizabeth K Speliotes et al.   NATURE GENETICS

Genotype imputation for genome-wide association studies

(2010) Jonathan Marchini et al.   NATURE REVIEWS GENETICS

NIR, an inhibitor of histone acetyltransferases, regulates transcription factor TAp63 and is controlled by the cell cycle

(2010) K. Heyne et al.   NUCLEIC ACIDS RESEARCH

MapSplice: Accurate mapping of RNA-seq reads for splice junction discovery

(2010) Kai Wang et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide Association Study of Pancreatic Cancer in Japanese Population

(2010) Siew-Kee Low et al.   PLoS One

The Tensin-3 Protein, Including its SH2 Domain, Is Phosphorylated by Src and Contributes to Tumorigenesis and Metastasis

(2009) Xiaolan Qian et al.   CANCER CELL

Pancreatic Exocrine Duct Cells Give Rise to Insulin-Producing β Cells during Embryogenesis but Not after Birth

(2009) Myriam Solar et al.   DEVELOPMENTAL CELL

Risk of Pancreatic Cancer in Families With Lynch Syndrome

(2009) Fay Kastrinos   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer

(2009) Laufey Amundadottir et al.   NATURE GENETICS

Exomic Sequencing Identifies PALB2 as a Pancreatic Cancer Susceptibility Gene

(2009) S. Jones et al.   SCIENCE

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

Practical aspects of imputation-driven meta-analysis of genome-wide association studies

(2008) P. I.W. de Bakker et al.   HUMAN MOLECULAR GENETICS