The pioneer factor activity of c-Myb involves recruitment of p300 and induction of histone acetylation followed by acetylation-induced chromatin dissociation

A TFIID-SAGA Perturbation that Targets MYB and Suppresses Acute Myeloid Leukemia

(2018) Yali Xu et al.   CANCER CELL

Widespread changes in nucleosome accessibility without changes in nucleosome occupancy during a rapid transcriptional induction

(2017) Britta Mueller et al.   GENES & DEVELOPMENT

A c-Myb mutant causes deregulated differentiation due to impaired histone binding and abrogated pioneer factor function

(2017) Bettina M. Fuglerud et al.   NUCLEIC ACIDS RESEARCH

PIAS1 binds p300 and behaves as a coactivator or corepressor of the transcription factor c-Myb dependent on SUMO-status

(2016) Marit Ledsaak et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Pioneer factors and ATP-dependent chromatin remodeling factors interact dynamically: A new perspective

(2016) Erin E. Swinstead et al.   BIOESSAYS

DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes

(2016) Si Ho Choi et al.   NUCLEIC ACIDS RESEARCH

Targeting acute myeloid leukemia with a small molecule inhibitor of the Myb/p300 interaction

(2015) Sagar Uttarkar et al.   BLOOD

Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes

(2014) D. R. Pattabiraman et al.   BLOOD

Chromatin remodeling mediated by the FOXA1/A2 transcription factors activatesCFTRexpression in intestinal epithelial cells

(2014) Jenny L Kerschner et al.   Epigenetics

Pioneer transcription factors in cell reprogramming

(2014) Makiko Iwafuchi-Doi et al.   GENES & DEVELOPMENT

Histone core modifications regulating nucleosome structure and dynamics

(2014) Peter Tessarz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element

(2014) M. R. Mansour et al.   SCIENCE

Targeted H3R26 Deimination Specifically Facilitates Estrogen Receptor Binding by Modifying Nucleosome Structure

(2014) Michael J. Guertin et al.   PLoS Genetics

Histone acetylation contributes to chromatin looping between the locus control region and globin gene by influencing hypersensitive site formation

(2013) Yea Woon Kim et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

PML4 facilitates erythroid differentiation by enhancing the transcriptional activity of GATA-1

(2013) J. Wu et al.   BLOOD

Modification of Enhancer Chromatin: What, How, and Why?

(2013) Eliezer Calo et al.   MOLECULAR CELL

Histone phosphorylation

(2012) Dorine Rossetto et al.   Epigenetics

The bromodomain interaction module

(2012) Panagis Filippakopoulos et al.   FEBS LETTERS

The accessible chromatin landscape of the human genome

(2012) Robert E. Thurman et al.   NATURE

Tissue-specific analysis of chromatin state identifies temporal signatures of enhancer activity during embryonic development

(2012) Stefan Bonn et al.   NATURE GENETICS

Functional and Mechanistic Diversity of Distal Transcription Enhancers

(2011) Michael Bulger et al.   CELL

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

Pioneer transcription factors: establishing competence for gene expression

(2011) K. S. Zaret et al.   GENES & DEVELOPMENT

An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance

(2011) J. Zuber et al.   GENES & DEVELOPMENT

A SUMO-regulated activation function controls synergy of c-Myb through a repressor–activator switch leading to differential p300 recruitment

(2010) Ann-Kristin Molværsmyr et al.   NUCLEIC ACIDS RESEARCH

Myb-induced Chromatin Remodeling at a Dual Enhancer/Promoter Element Involves Non-coding RNA Transcription and Is Disrupted by Oncogenic Mutations of v-myb

(2009) Carola Wilczek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

C/EBP  Induces Chromatin Opening at a Cell-Type-Specific Enhancer

(2008) A. Plachetka et al.   MOLECULAR AND CELLULAR BIOLOGY

Nucleosome destabilization in the epigenetic regulation of gene expression

(2007) Steven Henikoff   NATURE REVIEWS GENETICS