Chromatin remodeling mediated by the FOXA1/A2 transcription factors activatesCFTRexpression in intestinal epithelial cells

Immune Mediators Regulate CFTR Expression through a Bifunctional Airway-Selective Enhancer

(2013) Z. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

Nucleosome mapping across the CFTR locus identifies novel regulatory factors

(2013) Erbay Yigit et al.   NUCLEIC ACIDS RESEARCH

Transcriptional networks driving enhancer function in theCFTRgene

(2012) Jenny L. Kerschner et al.   BIOCHEMICAL JOURNAL

Enhancers: emerging roles in cell fate specification

(2012) Chin-Tong Ong et al.   EMBO REPORTS

GATA3 acts upstream of FOXA1 in mediating ESR1 binding by shaping enhancer accessibility

(2012) V. Theodorou et al.   GENOME RESEARCH

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Breast cancer risk–associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression

(2012) Richard Cowper-Sal·lari et al.   NATURE GENETICS

Functional and Mechanistic Diversity of Distal Transcription Enhancers

(2011) Michael Bulger et al.   CELL

Pioneer transcription factors: establishing competence for gene expression

(2011) K. S. Zaret et al.   GENES & DEVELOPMENT

Epigenetic switch involved in activation of pioneer factor FOXA1-dependent enhancers

(2011) A. A. Serandour et al.   GENOME RESEARCH

Molecular mechanisms controlling CFTR gene expression in the airway

(2011) Zhaolin Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

ENCODE whole-genome data in the UCSC Genome Browser: update 2012

(2011) K. R. Rosenbloom et al.   NUCLEIC ACIDS RESEARCH

CCCTC-binding Factor Acts Upstream of FOXA1 and Demarcates the Genomic Response to Estrogen

(2010) Yu Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A unique chromatin signature uncovers early developmental enhancers in humans

(2010) Alvaro Rada-Iglesias et al.   NATURE

Charting histone modifications and the functional organization of mammalian genomes

(2010) Vicky W. Zhou et al.   NATURE REVIEWS GENETICS

Cell-type-specific long-range looping interactions identify distant regulatory elements of the CFTR gene

(2010) Nele Gheldof et al.   NUCLEIC ACIDS RESEARCH

Histone H3K27ac separates active from poised enhancers and predicts developmental state

(2010) M. P. Creyghton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers

(2009) J. Eeckhoute et al.   GENOME RESEARCH

An oestrogen-receptor-α-bound human chromatin interactome

(2009) Melissa J. Fullwood et al.   NATURE

An insulator element 3′ to the CFTR gene binds CTCF and reveals an active chromatin hub in primary cells

(2009) Neil P. Blackledge et al.   NUCLEIC ACIDS RESEARCH

Intronic enhancers coordinate epithelial-specific looping of the active CFTR locus

(2009) C. J. Ott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FoxA1 Translates Epigenetic Signatures into Enhancer-Driven Lineage-Specific Transcription

(2008) Mathieu Lupien et al.   CELL

A complex intronic enhancer regulates expression of theCFTRgene by direct interaction with the promoter

(2008) Christopher J. Ott et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE