Various stress stimuli rewire the profile of liver secretome in a p53-dependent manner

Elevated Liver Enzymes: Emergency Department–Focused Management

(2017) Eric Sulava et al.   JOURNAL OF EMERGENCY MEDICINE

SERPINE2/Protease Nexin-1 in vivo multiple functions: Does the puzzle make sense?

(2017) Denis Monard   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

QuPath: Open source software for digital pathology image analysis

(2017) Peter Bankhead et al.   Scientific Reports

Lung Adenocarcinoma Distally Rewires Hepatic Circadian Homeostasis

(2016) Selma Masri et al.   CELL

Hypothesis: solid tumours behave as systemic metabolic dictators

(2016) Yang-Ming Lee et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

GeneAnalytics: An Integrative Gene Set Analysis Tool for Next Generation Sequencing, RNAseq and Microarray Data

(2016) Shani Ben-Ari Fuchs et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis

(2016) Megan K. Ruhland et al.   Nature Communications

Novel p53 target genes secreted by the liver are involved in non-cell-autonomous regulation

(2015) M Charni et al.   CELL DEATH AND DIFFERENTIATION

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Protease nexin 1 induces apoptosis of prostate tumor cells through inhibition of X-chromosome-linked inhibitor of apoptosis protein

(2015) Chad M. McKee et al.   Oncotarget

Intracellular role of exchangeable apolipoproteins in energy homeostasis, obesity and non-alcoholic fatty liver disease

(2014) Chen-Lu Wu et al.   BIOLOGICAL REVIEWS

The human liver-specific proteome defined by transcriptomics and antibody-based profiling

(2014) Caroline Kampf et al.   FASEB JOURNAL

p53 in liver pathologies—taking the good with the bad

(2014) Meital Charni et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Tumor Macroenvironment and Metabolism

(2014) Wael Al-Zhoughbi et al.   SEMINARS IN ONCOLOGY

Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms

(2014) Mary Ann Allen et al.   eLife

Non-Cell-Autonomous Tumor Suppression by p53

(2013) Amaia Lujambio et al.   CELL

Cathepsin B as a cancer target

(2013) Christopher S Gondi et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

PAI-1, progress in understanding the clinical problem and its aetiology

(2012) Takayuki Iwaki et al.   BRITISH JOURNAL OF HAEMATOLOGY

Chemotherapeutic agents induce the expression and activity of their clearing enzyme CYP3A4 by activating p53

(2012) Ido Goldstein et al.   CARCINOGENESIS

Immune surveillance of senescent cells--biological significance in cancer- and non-cancer pathologies

(2012) L. Hoenicke et al.   CARCINOGENESIS

Regulation of lipid metabolism by p53 – fighting two villains with one sword

(2012) Ido Goldstein et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Control of the senescence-associated secretory phenotype by NF- B promotes senescence and enhances chemosensitivity

(2011) Y. Chien et al.   GENES & DEVELOPMENT

p53, a novel regulator of lipid metabolism pathways

(2011) Ido Goldstein et al.   JOURNAL OF HEPATOLOGY

Drug-induced acute liver failure: Results of a U.S. multicenter, prospective study

(2010) Adrian Reuben et al.   HEPATOLOGY

Requirement of the ATM/p53 Tumor Suppressor Pathway for Glucose Homeostasis

(2010) H. L. Armata et al.   MOLECULAR AND CELLULAR BIOLOGY

The p53-cathepsin axis cooperates with ROS to activate programmed necrotic death upon DNA damage

(2009) H.-C. Tu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Senescence of Activated Stellate Cells Limits Liver Fibrosis

(2008) Valery Krizhanovsky et al.   CELL

Homeostatic functions of the p53 tumor suppressor: Regulation of energy metabolism and antioxidant defense

(2008) Ivan A. Olovnikov et al.   SEMINARS IN CANCER BIOLOGY

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY