Osteopontin promotes metastasis of intrahepatic cholangiocarcinoma through recruiting MAPK1 and mediating Ser675 phosphorylation of β-Catenin

Emerging molecular therapeutic targets for cholangiocarcinoma

(2017) Sumera Rizvi et al.   JOURNAL OF HEPATOLOGY

GOLM1 Modulates EGFR/RTK Cell-Surface Recycling to Drive Hepatocellular Carcinoma Metastasis

(2016) Qing-Hai Ye et al.   CANCER CELL

Nuclear phosphorylated Y142 β-catenin accumulates in astrocytomas and glioblastomas and regulates cell invasion

(2015) Mireia Náger et al.   CELL CYCLE

Molecular Pathogenesis and Targeted Therapies for Intrahepatic Cholangiocarcinoma

(2015) A. Moeini et al.   CLINICAL CANCER RESEARCH

IL-33 facilitates oncogene-induced cholangiocarcinoma in mice by an interleukin-6-sensitive mechanism

(2015) Daisaku Yamada et al.   HEPATOLOGY

WNT signaling drives cholangiocarcinoma growth and can be pharmacologically inhibited

(2015) Luke Boulter et al.   JOURNAL OF CLINICAL INVESTIGATION

Osteopontin-CD44 Signaling in the Glioma Perivascular Niche Enhances Cancer Stem Cell Phenotypes and Promotes Aggressive Tumor Growth

(2014) Alexander Pietras et al.   Cell Stem Cell

Blockade of CXCL12/CXCR4 signaling inhibits intrahepatic cholangiocarcinoma progression and metastasis via inactivation of canonical Wnt pathway

(2014) Shengqiang Zhao et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Guidelines for the diagnosis and management of intrahepatic cholangiocarcinoma

(2014) John Bridgewater et al.   JOURNAL OF HEPATOLOGY

Cholangiocarcinoma

(2014) Nataliya Razumilava et al.   LANCET

Pathogenesis, Diagnosis, and Management of Cholangiocarcinoma

(2013) Sumera Rizvi et al.   GASTROENTEROLOGY

Molecular profiling of stroma identifies osteopontin as an independent predictor of poor prognosis in intrahepatic cholangiocarcinoma

(2013) Laurent Sulpice et al.   HEPATOLOGY

Changing pattern of epidemiology in intrahepatic cholangiocarcinoma

(2013) Basile Njei   HEPATOLOGY

Gankyrin promotes tumor growth and metastasis through activation of IL-6/STAT3 signaling in human cholangiocarcinoma

(2013) Tongsen Zheng et al.   HEPATOLOGY

Intrahepatic cholangiocarcinoma: pathogenesis and rationale for molecular therapies

(2013) D Sia et al.   ONCOGENE

MicroRNA-26a Promotes Cholangiocarcinoma Growth by Activating β-catenin

(2012) Jinqiang Zhang et al.   GASTROENTEROLOGY

Osteopontin promoter polymorphisms at locus -443 significantly affect the metastasis and prognosis of human hepatocellular carcinoma

(2012) Qiong-Zhu Dong et al.   HEPATOLOGY

Osteopontin, an oxidant stress sensitive cytokine, up-regulates collagen-I via integrin αVβ3 engagement and PI3K/pAkt/NFκB signaling

(2011) Raquel Urtasun et al.   HEPATOLOGY

Intrahepatic Cholangiocarcinoma: An International Multi-Institutional Analysis of Prognostic Factors and Lymph Node Assessment

(2011) Mechteld C. de Jong et al.   JOURNAL OF CLINICAL ONCOLOGY

A Rac1/PAK1 cascade controls β-catenin activation in colon cancer cells

(2011) G Zhu et al.   ONCOGENE

Thrombin is a therapeutic target for metastatic osteopontin-positive hepatocellular carcinoma

(2010) Yu-Hua Xue et al.   HEPATOLOGY

Cyclooxygenase-2 Derived Prostaglandin E2 Activates -Catenin in Human Cholangiocarcinoma Cells: Evidence for Inhibition of These Signaling Pathways by  3 Polyunsaturated Fatty Acids

(2008) K. Lim et al.   CANCER RESEARCH

Rac1 Activation Controls Nuclear Localization of β-catenin during Canonical Wnt Signaling

(2008) Ximei Wu et al.   CELL

Systemic Endocrine Instigation of Indolent Tumor Growth Requires Osteopontin

(2008) Sandra S. McAllister et al.   CELL

Lentiviral-mediated miRNA against osteopontin suppresses tumor growth and metastasis of human hepatocellular carcinoma

(2008) Bing-Sheng Sun et al.   HEPATOLOGY

High Expression of Macrophage Colony-Stimulating Factor in Peritumoral Liver Tissue Is Associated With Poor Survival After Curative Resection of Hepatocellular Carcinoma

(2008) Xiao-Dong Zhu et al.   JOURNAL OF CLINICAL ONCOLOGY

Identification of osteopontin as the most consistently over-expressed gene in intrahepatic cholangiocarcinoma: Detection by oligonucleotide microarray and real-time PCR analysis

(2008) Holger G Hass et al.   WORLD JOURNAL OF GASTROENTEROLOGY