Type 2 NADH Dehydrogenase Is the Only Point of Entry for Electrons into the Streptococcus agalactiae Respiratory Chain and Is a Potential Drug Target

Target Elucidation by Cocrystal Structures of NADH-Ubiquinone Oxidoreductase of Plasmodium falciparum (PfNDH2) with Small Molecule To Eliminate Drug-Resistant Malaria

(2017) Yiqing Yang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Visualization of the role of host heme on the virulence of the heme auxotroph Streptococcus agalactiae

(2017) Laetitia Joubert et al.   Scientific Reports

Acid Stress Response Mechanisms of Group B Streptococci

(2017) Sarah Shabayek et al.   Frontiers in Cellular and Infection Microbiology

Crystal structure of type II NADH:quinone oxidoreductase from Caldalkalibacillus thermarum with an improved resolution of 2.15 Å

(2017) Yoshio Nakatani et al.   Acta Crystallographica Section F-Structural Biology Communications

Oxidant Mechanisms in Renal Injury and Disease

(2016) Brian B. Ratliff et al.   ANTIOXIDANTS & REDOX SIGNALING

A partial metabolic pathway enables group b streptococcus to overcome quinone deficiency in a host bacterial community

(2016) Thierry Franza et al.   MOLECULAR MICROBIOLOGY

Streptococcal toxins: role in pathogenesis and disease

(2015) Timothy C. Barnett et al.   CELLULAR MICROBIOLOGY

Characterization of the type 2 NADH:menaquinone oxidoreductases from Staphylococcus aureus and the bactericidal action of phenothiazines

(2014) Lici A. Schurig-Briccio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Early adaptation to oxygen is key to the industrially important traits of Lactococcus lactis ssp. cremoris during milk fermentation

(2014) Marina Cretenet et al.   BMC GENOMICS

Recent trends in the metabolism and cell biology of vitamin K with special reference to vitamin K cycling and MK-4 biosynthesis

(2014) Martin J. Shearer et al.   JOURNAL OF LIPID RESEARCH

Structure of the bacterial type II NADH dehydrogenase: a monotopic membrane protein with an essential role in energy generation

(2014) Adam Heikal et al.   MOLECULAR MICROBIOLOGY

Deciphering key features in protein structures with the new ENDscript server

(2014) Xavier Robert et al.   NUCLEIC ACIDS RESEARCH

Zafirlukast Inhibits Complexation of Lsr2 with DNA and Growth of Mycobacterium tuberculosis

(2013) Lucile Pinault et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Alternate pathways for NADH oxidation in Thermus thermophilus using type 2 NADH dehydrogenases

(2013) Padmaja Venkatakrishnan et al.   BIOLOGICAL CHEMISTRY

Reductive evolution in Streptococcus agalactiae and the emergence of a host adapted lineage

(2013) Isabelle Rosinski-Chupin et al.   BMC GENOMICS

A hemolytic pigment of Group B Streptococcus allows bacterial penetration of human placenta

(2013) Christopher Whidbey et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Nuclease A (Gbs0661), an extracellular nuclease ofStreptococcus agalactiae, attacks the neutrophil extracellular traps and is needed for full virulence

(2013) Aurélie Derré-Bobillot et al.   MOLECULAR MICROBIOLOGY

Structural insight into the type-II mitochondrial NADH dehydrogenases

(2012) Yue Feng et al.   NATURE

The structure of the yeast NADH dehydrogenase (Ndi1) reveals overlapping binding sites for water- and lipid-soluble substrates

(2012) M. Iwata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria

(2012) G. A. Biagini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aerobic Respiration Metabolism in Lactic Acid Bacteria and Uses in Biotechnology

(2012) Martin B. Pedersen et al.   Annual Review of Food Science and Technology

The cytochrome bd respiratory oxygen reductases

(2011) Vitaliy B. Borisov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Immune Activation and Suppression by Group B Streptococcus in a Murine Model of Urinary Tract Infection

(2011) Kimberly A. Kline et al.   INFECTION AND IMMUNITY

Identification of a Lactate-Quinone Oxidoreductase in Staphylococcus aureus that is Essential for Virulence

(2011) James R. Fuller et al.   Frontiers in Cellular and Infection Microbiology

Two Coregulated Efflux Transporters Modulate Intracellular Heme and Protoporphyrin IX Availability in Streptococcus agalactiae

(2010) Annabelle Fernandez et al.   PLoS Pathogens

Structural and Functional Insights into Sulfide:Quinone Oxidoreductase,

(2009) José A. Brito et al.   BIOCHEMISTRY

Type II NADH Dehydrogenase Inhibitor 1-Hydroxy-2-Dodecyl- 4(1H)Quinolone Leads to Collapse of Mitochondrial Inner- Membrane Potential and ATP Depletion inToxoplasma gondii

(2009) San San Lin et al.   EUKARYOTIC CELL

Type II fatty acid synthesis is not a suitable antibiotic target for Gram-positive pathogens

(2009) Sophie Brinster et al.   NATURE

Purification of two putative type II NADH dehydrogenases with different substrate specificities from alkaliphilic Bacillus pseudofirmus OF4

(2008) Jun Liu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Lactococcus lactis produces short-chain quinones that cross-feed Group B Streptococcus to activate respiration growth

(2008) Lahcen Rezaïki et al.   MOLECULAR MICROBIOLOGY

Structure of α-Glycerophosphate Oxidase fromStreptococcussp.:  A Template for the Mitochondrial α-Glycerophosphate Dehydrogenase†,‡

(2007) Timothy Colussi et al.   BIOCHEMISTRY