Cortical GABAergic Interneuron/Progenitor Transplantation as a Novel Therapy for Intractable Epilepsy

A survey of antiepileptic drug responses identifies drugs with potential efficacy for seizure control in Wolf–Hirschhorn syndrome

(2018) Karen S. Ho et al.   EPILEPSY & BEHAVIOR

Surgical versus medical treatment of drug-resistant epilepsy: A systematic review and meta-analysis

(2018) Jin-tao Liu et al.   EPILEPSY & BEHAVIOR

Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology

(2017) Robert S. Fisher et al.   EPILEPSIA

ILAE classification of the epilepsies: Position paper of the ILAE Commission for Classification and Terminology

(2017) Ingrid E. Scheffer et al.   EPILEPSIA

Hippocampal GABAergic Inhibitory Interneurons

(2017) Kenneth A. Pelkey et al.   PHYSIOLOGICAL REVIEWS

Chemical Control of Grafted Human PSC-Derived Neurons in a Mouse Model of Parkinson’s Disease

(2016) Yuejun Chen et al.   Cell Stem Cell

Hilar somatostatin interneuron loss reduces dentate gyrus inhibition in a mouse model of temporal lobe epilepsy

(2016) Gabrielle Hofmann et al.   EPILEPSIA

Stem cell-derived interneuron transplants as a treatment for schizophrenia: preclinical validation in a rodent model

(2016) J J Donegan et al.   MOLECULAR PSYCHIATRY

The Epidemiology of Global Epilepsy

(2016) Anuradha Singh et al.   NEUROLOGIC CLINICS

Interneuron Progenitor Transplantation to Treat CNS Dysfunction

(2016) Muhammad O. Chohan et al.   Frontiers in Neural Circuits

A Closed Loop Brain-machine Interface for Epilepsy Control Using Dorsal Column Electrical Stimulation

(2016) Miguel Pais-Vieira et al.   Scientific Reports

The Use of DREADDs to Deconstruct Behavior

(2016) Paul D. Whissell et al.   Frontiers in Genetics

Resective Epilepsy Surgery for Drug-Resistant Focal Epilepsy

(2015) Barbara C. Jobst et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Interneuron Transplantation as a Treatment for Epilepsy

(2015) Robert F. Hunt et al.   Cold Spring Harbor Perspectives in Medicine

Electrophysiology in epilepsy surgery: Roles and limitations

(2014) EdwardH Bertram   Annals of Indian Academy of Neurology

Approaches to refractory epilepsy

(2014) Jerome Engel   Annals of Indian Academy of Neurology

hPSC-Derived Maturing GABAergic Interneurons Ameliorate Seizures and Abnormal Behavior in Epileptic Mice

(2014) Miles Cunningham et al.   Cell Stem Cell

Transplantation of GABAergic Interneurons into the Neonatal Primary Visual Cortex Reduces Absence Seizures in Stargazer Mice

(2014) Mohamed Hammad et al.   CEREBRAL CORTEX

Two-year seizure reduction in adults with medically intractable partial onset epilepsy treated with responsive neurostimulation: Final results of the RNS System Pivotal trial

(2014) Christianne N. Heck et al.   EPILEPSIA

The consequences of refractory epilepsy and its treatment

(2014) Kenneth D. Laxer et al.   EPILEPSY & BEHAVIOR

Long-Term Seizure Suppression and Optogenetic Analyses of Synaptic Connectivity in Epileptic Mice with Hippocampal Grafts of GABAergic Interneurons

(2014) K. W. Henderson et al.   JOURNAL OF NEUROSCIENCE

Interneurons from Embryonic Development to Cell-Based Therapy

(2014) D. G. Southwell et al.   SCIENCE

Banking on iPSC- Is it Doable and is it Worthwhile

(2014) Susan Solomon et al.   Stem Cell Reviews and Reports

Efficient Specification of Interneurons from Human Pluripotent Stem Cells by Dorsoventral and Rostrocaudal Modulation

(2014) Tae-Gon Kim et al.   STEM CELLS

GABAergic interneuron transplants to study development and treat disease

(2014) Jennifer A. Tyson et al.   TRENDS IN NEUROSCIENCES

Directed Differentiation and Functional Maturation of Cortical Interneurons from Human Embryonic Stem Cells

(2013) Asif M. Maroof et al.   Cell Stem Cell

Functional Maturation of hPSC-Derived Forebrain Interneurons Requires an Extended Timeline and Mimics Human Neural Development

(2013) Cory R. Nicholas et al.   Cell Stem Cell

Cortical interneurons that specialize in disinhibitory control

(2013) Hyun-Jae Pi et al.   NATURE

Medial ganglionic eminence–like cells derived from human embryonic stem cells correct learning and memory deficits

(2013) Yan Liu et al.   NATURE BIOTECHNOLOGY

GABA progenitors grafted into the adult epileptic brain control seizures and abnormal behavior

(2013) Robert F Hunt et al.   NATURE NEUROSCIENCE

Closed-loop optogenetic intervention in mice

(2013) Caren Armstrong et al.   Nature Protocols

Directed differentiation of forebrain GABA interneurons from human pluripotent stem cells

(2013) Yan Liu et al.   Nature Protocols

Mechanisms of epileptogenesis: a convergence on neural circuit dysfunction

(2013) Ethan M. Goldberg et al.   NATURE REVIEWS NEUROSCIENCE

Derivation and Isolation of NKX2.1-Positive Basal Forebrain Progenitors from Human Embryonic Stem Cells

(2013) Noélle D. Germain et al.   STEM CELLS AND DEVELOPMENT

Hilar mossy cells of the dentate gyrus: a historical perspective

(2013) Helen E. Scharfman et al.   Frontiers in Neural Circuits

On-demand optogenetic control of spontaneous seizures in temporal lobe epilepsy

(2013) Esther Krook-Magnuson et al.   Nature Communications

Development and specification of GABAergic cortical interneurons

(2013) Corey Kelsom et al.   Cell and Bioscience

Generating an iPSC Bank for HLA-Matched Tissue Transplantation Based on Known Donor and Recipient HLA Types

(2012) Craig J. Taylor et al.   Cell Stem Cell

Teratocarcinoma Formation in Embryonic Stem Cell-Derived Neural Progenitor Hippocampal Transplants

(2012) Noélle D. Germain et al.   CELL TRANSPLANTATION

Anticonvulsant Effects by Bilateral and Unilateral Transplantation of GABA-Producing Cells into the Subthalamic Nucleus in an Acute Seizure Model

(2012) Annelie Handreck et al.   CELL TRANSPLANTATION

Differentiation and Functional Incorporation of Embryonic Stem Cell-Derived GABAergic Interneurons in the Dentate Gyrus of Mice with Temporal Lobe Epilepsy

(2012) X. Maisano et al.   JOURNAL OF NEUROSCIENCE

Epileptic EEG classification based on extreme learning machine and nonlinear features

(2011) Qi Yuan et al.   EPILEPSY RESEARCH

The long-term outcome of adult epilepsy surgery, patterns of seizure remission, and relapse: a cohort study

(2011) Jane de Tisi et al.   LANCET

A Targeted NKX2.1 Human Embryonic Stem Cell Reporter Line Enables Identification of Human Basal Forebrain Derivatives

(2011) Adam L. Goulburn et al.   STEM CELLS

Embryonic MGE Precursor Cells Grafted into Adult Rat Striatum Integrate and Ameliorate Motor Symptoms in 6-OHDA-Lesioned Rats

(2010) Verónica Martínez-Cerdeño et al.   Cell Stem Cell

Effect of neuronal precursor cells derived from medial ganglionic eminence in an acute epileptic seizure model

(2010) Maria E. Calcagnotto et al.   EPILEPSIA

Intractable Epilepsy: Relapsing, Remitting, or Progressive?

(2010) Susan Herman   Epilepsy Currents

Variation in the safety of induced pluripotent stem cell lines

(2009) Kyoko Miura et al.   NATURE BIOTECHNOLOGY

Reduction of seizures by transplantation of cortical GABAergic interneuron precursors into Kv1.1 mutant mice

(2009) S. C. Baraban et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Safety and Function of a New Clinical Intracerebral Microinjection Instrument for Stem Cells and Therapeutics Examined in the Göttingen Minipig

(2009) Carsten R. Bjarkam et al.   STEREOTACTIC AND FUNCTIONAL NEUROSURGERY

Grafting of striatal precursor cells into hippocampus shortly after status epilepticus restrains chronic temporal lobe epilepsy

(2008) Bharathi Hattiangady et al.   EXPERIMENTAL NEUROLOGY