Stem cell-derived interneuron transplants as a treatment for schizophrenia: preclinical validation in a rodent model

Duration of culture and sonic hedgehog signaling differentially specify PV versus SST cortical interneuron fates from embryonic stem cells

(2015) J. A. Tyson et al.   DEVELOPMENT

Moving Stem Cells to the Clinic: Potential and Limitations for Brain Repair

(2015) Julius A. Steinbeck et al.   NEURON

Determinants of different aspects of everyday outcome in schizophrenia: The roles of negative symptoms, cognition, and functional capacity

(2015) Martin T. Strassnig et al.   SCHIZOPHRENIA RESEARCH

GABAergic mechanisms of hippocampal hyperactivity in schizophrenia

(2015) Stephan Heckers et al.   SCHIZOPHRENIA RESEARCH

An augmented dopamine system function is present prior to puberty in the methylazoxymethanol acetate rodent model of schizophrenia

(2014) Li Chen et al.   Developmental Neurobiology

Unmet Needs in the Treatment of Schizophrenia

(2014) Leslie Citrome   JOURNAL OF CLINICAL PSYCHIATRY

Interneuron precursor transplants in adult hippocampus reverse psychosis-relevant features in a mouse model of hippocampal disinhibition

(2014) A. I. Gilani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A fundamental role for hippocampal parvalbumin in the dopamine hyperfunction associated with schizophrenia

(2014) Angela M. Boley et al.   SCHIZOPHRENIA RESEARCH

The protracted maturation of human ESC-derived interneurons

(2013) Jennifer A Tyson et al.   CELL CYCLE

Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis

(2013) Stefan Leucht et al.   LANCET

Hippocampal interneuron transplants reverse aberrant dopamine system function and behavior in a rodent model of schizophrenia

(2013) S M Perez et al.   MOLECULAR PSYCHIATRY

Spatial and Temporal Bias in the Mitotic Origins of Somatostatin- and Parvalbumin-Expressing Interneuron Subgroups and the Chandelier Subtype in the Medial Ganglionic Eminence

(2011) M. Inan et al.   CEREBRAL CORTEX

Dopamine, But Not Serotonin, Regulates Reversal Learning in the Marmoset Caudate Nucleus

(2011) H. F. Clarke et al.   JOURNAL OF NEUROSCIENCE

Neocortical excitation/inhibition balance in information processing and social dysfunction

(2011) Ofer Yizhar et al.   NATURE

Selective Remediation of Reversal Learning Deficits in the Neurodevelopmental MAM Model of Schizophrenia by a Novel mGlu5 Positive Allosteric Modulator

(2011) Francois Gastambide et al.   NEUROPSYCHOPHARMACOLOGY

Hippocampal interneurons are abnormal in schizophrenia

(2011) Christine Konradi et al.   SCHIZOPHRENIA RESEARCH

Hippocampal dysregulation of dopamine system function and the pathophysiology of schizophrenia

(2011) Daniel J. Lodge et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Learning and cognitive flexibility: frontostriatal function and monoaminergic modulation

(2010) Angie A Kehagia et al.   CURRENT OPINION IN NEUROBIOLOGY

Sonic Hedgehog Signaling Confers Ventral Telencephalic Progenitors with Distinct Cortical Interneuron Fates

(2010) Qing Xu et al.   NEURON

Differential Targeting of the CA1 Subfield of the Hippocampal Formation by Schizophrenia and Related Psychotic Disorders

(2009) Scott A. Schobel et al.   ARCHIVES OF GENERAL PSYCHIATRY

Gestational methylazoxymethanol acetate administration: A developmental disruption model of schizophrenia

(2009) Daniel J. Lodge et al.   BEHAVIOURAL BRAIN RESEARCH

Discrimination Learning, Reversal, and Set-Shifting in First-Episode Schizophrenia: Stability Over Six Years and Specific Associations with Medication Type and Disorganization Syndrome

(2009) Verity C. Leeson et al.   BIOLOGICAL PSYCHIATRY

Dopamine DRD2 Polymorphism Alters Reversal Learning and Associated Neural Activity

(2009) G. Jocham et al.   JOURNAL OF NEUROSCIENCE

Striatal Dopamine Predicts Outcome-Specific Reversal Learning and Its Sensitivity to Dopaminergic Drug Administration

(2009) R. Cools et al.   JOURNAL OF NEUROSCIENCE

Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years

(2008) Ivar Mendez et al.   NATURE MEDICINE

Dopamine D2/D3 receptor agonist quinpirole impairs spatial reversal learning in rats: investigation of D3 receptor involvement in persistent behavior

(2008) Vasileios Boulougouris et al.   PSYCHOPHARMACOLOGY

A spatial bias for the origins of interneuron subgroups within the medial ganglionic eminence

(2007) Carl P. Wonders et al.   DEVELOPMENTAL BIOLOGY