Apelin in Reproductive Physiology and Pathology of Different Species: A Critical Review

Apelin and apelin receptor at different stages of corpus luteum development and effect of apelin on progesterone secretion and 3β-hydroxysteroid dehydrogenase (3β-HSD) in pigs

(2018) Marta Różycka et al.   ANIMAL REPRODUCTION SCIENCE

Expression of apelin and apelin receptor (APJ) in porcine ovarian follicles and in vitro effect of apelin on steroidogenesis and proliferation through APJ activation and different signaling pathways

(2017) A. Rak et al.   THERIOGENOLOGY

Bisphenol A and its derivatives tetrabromobisphenol A and tetrachlorobisphenol A induce apelin expression and secretion in ovarian cancer cells through a peroxisome proliferator-activated receptor gamma-dependent mechanism

(2017) Marta Hoffmann et al.   TOXICOLOGY LETTERS

Dynamic Expression of Apelin and Its Receptor in the Primate Preovulatory Follicle and Corpus Luteum During the Menstrual Cycle.

(2017) Fuhua Xu et al.   BIOLOGY OF REPRODUCTION

Apelin (APLN) and Apelin Receptor (APLNR) in Human Ovary: Expression, Signaling, and Regulation of Steroidogenesis in Primary Human Luteinized Granulosa Cells

(2016) J. Roche et al.   BIOLOGY OF REPRODUCTION

Is there association between vitamin D levels, apelin 36, and visfatin in PCOS?

(2016) Emel Kiyak Caglayan et al.   GYNECOLOGICAL ENDOCRINOLOGY

Angiotensin-Converting Enzyme 2 Metabolizes and Partially Inactivates Pyr-Apelin-13 and Apelin-17Novelty and Significance

(2016) Wang Wang et al.   HYPERTENSION

Adipose tissue in control of metabolism

(2016) Liping Luo et al.   JOURNAL OF ENDOCRINOLOGY

Apelin-13 protects against apoptosis by activating AMP-activated protein kinase pathway in ischemia stroke

(2016) Yi Yang et al.   PEPTIDES

Central chronic apelin infusion decreases energy expenditure and thermogenesis in mice

(2016) Anne Drougard et al.   Scientific Reports

Polycystic ovary syndrome

(2016) Ricardo Azziz et al.   Nature Reviews Disease Primers

Characterization of apela, a novel endogenous ligand of apelin receptor, in the adult heart

(2015) Ábel Perjés et al.   BASIC RESEARCH IN CARDIOLOGY

New structural insights into the apelin receptor: identification of key residues for apelin binding

(2015) Romain Gerbier et al.   FASEB JOURNAL

The effects of intracerebroventricular infusion of apelin-13 on reproductive function in male rats

(2015) Suleyman Sandal et al.   NEUROSCIENCE LETTERS

Evaluation of Apelin and Insulin Resistance in Patients with PCOS and Therapeutic Effect of Drospirenone-Ethinylestradiol Plus Metformin

(2015) Xianchang Sun et al.   MEDICAL SCIENCE MONITOR

Apelin promotes lymphangiogenesis and lymph node metastasis

(2015) Judit Berta et al.   Oncotarget

The apelin receptor: physiology, pathology, cell signalling, and ligand modulation of a peptide-activated class A GPCR

(2014) Nigel A. Chapman et al.   Biochemistry and Cell Biology

Apelin levels in relation with hormonal and metabolic profile in patients with polycystic ovary syndrome

(2014) Sündüz Özlem Altinkaya et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

Apelin-13 Attenuates Traumatic Brain Injury-Induced Damage by Suppressing Autophagy

(2014) Hai-Jun Bao et al.   NEUROCHEMICAL RESEARCH

Toddler: An Embryonic Signal That Promotes Cell Movement via Apelin Receptors

(2014) A. Pauli et al.   SCIENCE

Pyroglutamyl apelin-13 identified as the major apelin isoform in human plasma

(2013) Eugene Y. Zhen et al.   ANALYTICAL BIOCHEMISTRY

ELABELA: A Hormone Essential for Heart Development Signals via the Apelin Receptor

(2013) Serene C. Chng et al.   DEVELOPMENTAL CELL

Tumour co-expression of apelin and its receptor is the basis of an autocrine loop involved in the growth of colon adenocarcinomas

(2013) François-Xavier Picault et al.   EUROPEAN JOURNAL OF CANCER

Apelin Attenuates Oxidative Stress in Human Adipocytes

(2013) Aung Than et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The apelin receptor APJ: journey from an orphan to a multifaceted regulator of homeostasis

(2013) Anne-Marie O'Carroll et al.   JOURNAL OF ENDOCRINOLOGY

Apelin-13 increases myocardial progenitor cells and improves repair postmyocardial infarction

(2012) Lanfang Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Circulating apelin level in relation to nutritional status in polycystic ovary syndrome and its association with metabolic and hormonal disturbances

(2012) Magdalena Olszanecka-Glinianowicz et al.   CLINICAL ENDOCRINOLOGY

THE EXPRESSION OF APELIN AND ITS RECEPTOR APJ DURING DIFFERENT PHYSIOLOGICAL STAGES IN THE BOVINE OVARY

(2012) Stefanie Schilffarth et al.   International Journal of Biological Sciences

Stress-dependent and gender-specific neuroregulatory roles of the apelin receptor in the hypothalamic–pituitary–adrenal axis response to acute stress

(2012) M J F Newson et al.   JOURNAL OF ENDOCRINOLOGY

Hypoxia-induced up-regulation of apelin is associated with a poor prognosis in oral squamous cell carcinoma patients

(2012) Kyun Heo et al.   ORAL ONCOLOGY

Apelin and the proopiomelanocortin system: a new regulatory pathway of hypothalamic α-MSH release

(2011) Annabelle Reaux-Le Goazigo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Data Supporting a New Physiological Role for Brain Apelin in the Regulation of Hypothalamic Oxytocin Neurons in Lactating Rats

(2011) Laurence Bodineau et al.   ENDOCRINOLOGY

Lower serum apelin levels in women with polycystic ovary syndrome

(2011) Chung-Yu Chang et al.   FERTILITY AND STERILITY

Global Patterns of Cancer Incidence and Mortality Rates and Trends

(2010) A. Jemal et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Apelin Decreases Lipolysis via Gq, Gi, and AMPK-Dependent Mechanisms

(2010) Patrick Yue et al.   ENDOCRINOLOGY

Neuroprotective effect of the endogenous neural peptide apelin in cultured mouse cortical neurons

(2010) Xiang Jun Zeng et al.   EXPERIMENTAL CELL RESEARCH

Activation of catalase by apelin prevents oxidative stress-linked cardiac hypertrophy

(2010) Camille Foussal et al.   FEBS LETTERS

International Union of Basic and Clinical Pharmacology. LXXIV. Apelin Receptor Nomenclature, Distribution, Pharmacology, and Function

(2010) S. L. Pitkin et al.   PHARMACOLOGICAL REVIEWS

Apelin and APJ receptor expression in granulosa and theca cells during different stages of follicular development in the bovine ovary: Involvement of apoptosis and hormonal regulation

(2009) Takashi Shimizu et al.   ANIMAL REPRODUCTION SCIENCE

[Pyr 1 ]Apelin-13 Identified as the Predominant Apelin Isoform in the Human Heart

(2009) Janet J. Maguire et al.   HYPERTENSION

The effects of apelin on hypothalamic–pituitary–adrenal axis neuroendocrine function are mediated through corticotrophin-releasing factor- and vasopressin-dependent mechanisms

(2009) Michael J F Newson et al.   JOURNAL OF ENDOCRINOLOGY

Supraspinal administration of apelin-13 induces antinociception via the opioid receptor in mice

(2009) Ning Xu et al.   PEPTIDES

Apelin-13 induces ERK1/2 but not p38 MAPK activation through coupling of the human apelin receptor to the Gi2pathway

(2008) Bo Bai et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

The Effects of Apelin on the Electrical Activity of Hypothalamic Magnocellular Vasopressin and Oxytocin Neurons and Somatodendritic Peptide Release

(2008) Vicky A. Tobin et al.   ENDOCRINOLOGY

Effect of hypocaloric diet-induced weight loss in obese women on plasma apelin and adipose tissue expression of apelin and APJ.

(2008) Isabelle Castan-Laurell et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Expression and localization of apelin and its receptor APJ in the bovine corpus luteum during the estrous cycle and prostaglandin F2 -induced luteolysis

(2008) K. Shirasuna et al.   REPRODUCTION