Construction of histidine-containing hydrocarbon stapled cell penetrating peptides for in vitro and in vivo delivery of siRNAs

Intercalation-mediated nucleic acid nanoparticles for siRNA delivery

(2016) Kejin Zhou et al.   CHEMICAL COMMUNICATIONS

Development of Cell-Penetrating Asymmetric Interfering RNA Targeting Connective Tissue Growth Factor

(2016) Jihye Hwang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Structural Analysis of Human Argonaute-2 Bound to a Modified siRNA Guide

(2016) Nicole T. Schirle et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biophysical determinants for cellular uptake of hydrocarbon-stapled peptide helices

(2016) Gregory H Bird et al.   Nature Chemical Biology

Transdermal Delivery of siRNA through Microneedle Array

(2016) Yan Deng et al.   Scientific Reports

Cell-Penetrating, Dimeric α-Helical Peptides: Nanomolar Inhibitors of HIV-1 Transcription

(2014) Sangmok Jang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In vivo gene silencing following non-invasive siRNA delivery into the skin using a novel topical formulation

(2014) Vikas Hegde et al.   JOURNAL OF CONTROLLED RELEASE

Hydrocarbon-Stapled Peptides: Principles, Practice, and Progress

(2014) Loren D. Walensky et al.   JOURNAL OF MEDICINAL CHEMISTRY

The multiple roles of histidine in protein interactions

(2013) Si-Ming Liao et al.   Chemistry Central Journal

Delivery materials for siRNA therapeutics

(2013) Rosemary Kanasty et al.   NATURE MATERIALS

siRNA Delivery: From Lipids to Cell-penetrating Peptides and Their Mimics

(2012) Matt Gooding et al.   Chemical Biology & Drug Design

Cell-penetrating Peptides as Versatile Vehicles for Oligonucleotide Delivery

(2012) Helerin Margus et al.   MOLECULAR THERAPY

siRNA-optimized Modifications for Enhanced In Vivo Activity

(2012) Denise M Kenski et al.   Molecular Therapy-Nucleic Acids

Efficient Intracellular Delivery of Nucleic Acid Pharmaceuticals Using Cell-Penetrating Peptides

(2011) Ikuhiko Nakase et al.   ACCOUNTS OF CHEMICAL RESEARCH

A simple, noninvasive and efficient method for transdermal delivery of siRNA

(2011) Chang-Min Lin et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Protein transduction domain delivery of therapeutic macromolecules

(2011) Arjen van den Berg et al.   CURRENT OPINION IN BIOTECHNOLOGY

Endosome maturation

(2011) Jatta Huotari et al.   EMBO JOURNAL

Use of Self-Delivery siRNAs to Inhibit Gene Expression in an Organotypic Pachyonychia Congenita Model

(2011) Robyn P. Hickerson et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Comparison of Cationic and Amphipathic Cell Penetrating Peptides for siRNA Delivery and Efficacy

(2011) Robert H. Mo et al.   MOLECULAR PHARMACEUTICS

SiRNA delivery with exosome nanoparticles

(2011) Jasper G van den Boorn et al.   NATURE BIOTECHNOLOGY

Synthesis of all-hydrocarbon stapled α-helical peptides by ring-closing olefin metathesis

(2011) Young-Woo Kim et al.   Nature Protocols

Delivery of siRNA Therapeutics: Barriers and Carriers

(2010) Jie Wang et al.   AAPS Journal

RNA Grooves Can Accommodate Disulfide-Bridged Bundles of α-Helical Peptides

(2010) Soonsil Hyun et al.   CHEMBIOCHEM

Chemical vectors for gene delivery: a current review on polymers, peptides and lipids containing histidine or imidazole as nucleic acids carriers

(2009) Patrick Midoux et al.   BRITISH JOURNAL OF PHARMACOLOGY

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

siRNA silencing of keratinocyte-specific GFP expression in a transgenic mouse skin model

(2009) E Gonzalez-Gonzalez et al.   GENE THERAPY

An Approach to the Construction of Tailor-Made Amphiphilic Peptides That Strongly and Selectively Bind to Hairpin RNA Targets

(2009) Su Jin Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

Amphiphilic Helical Peptides Containing Two Acridine Moieties Display Picomolar Affinity toward HIV-1 RRE and TAR

(2007) Yeongran Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION