Phage-Derived Peptidoglycan Degrading Enzymes: Challenges and Future Prospects for In Vivo Therapy
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Title
Phage-Derived Peptidoglycan Degrading Enzymes: Challenges and Future Prospects for In Vivo Therapy
Authors
Keywords
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Journal
Viruses-Basel
Volume 10, Issue 6, Pages 292
Publisher
MDPI AG
Online
2018-05-30
DOI
10.3390/v10060292
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Note: Only part of the references are listed.- Chemotherapy with Phage Lysins Reduces Pneumococcal Colonization of the Respiratory Tract
- (2018) Bruno Corsini et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
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- (2018) ZhaoFei Wang et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Estimates of the global, regional, and national morbidity, mortality, and aetiologies of lower respiratory tract infections in 195 countries: a systematic analysis for the Global Burden of Disease Study 2015
- (2017) Christopher Troeger et al. LANCET INFECTIOUS DISEASES
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- (2017) Daniel B. Gilmer et al. PLoS One
- A novel chimeric lysin with robust antibacterial activity against planktonic and biofilm methicillin-resistant Staphylococcus aureus
- (2017) Hang Yang et al. Scientific Reports
- Endolysin LysEF-P10 shows potential as an alternative treatment strategy for multidrug-resistant Enterococcus faecalis infections
- (2017) Mengjun Cheng et al. Scientific Reports
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- (2017) Shih-Yi Peng et al. Scientific Reports
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- (2016) Hugo Oliveira et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
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- (2016) Shivani Chopra et al. INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
- More than a hole: the holin lethal function may be required to fully sensitize bacteria to the lytic action of canonical endolysins
- (2016) Sofia Fernandes et al. MOLECULAR MICROBIOLOGY
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- (2016) Catherine Jia-Yun Tsai et al. Virulence
- A bacteriophage endolysin that eliminates intracellular streptococci
- (2016) Yang Shen et al. eLife
- Structural and Enzymatic Characterization of ABgp46, a Novel Phage Endolysin with Broad Anti-Gram-Negative Bacterial Activity
- (2016) Hugo Oliveira et al. Frontiers in Microbiology
- Triple-acting Lytic Enzyme Treatment of Drug-Resistant and Intracellular Staphylococcus aureus
- (2016) Stephen C. Becker et al. Scientific Reports
- LysGH15 kills Staphylococcus aureus without being affected by the humoral immune response or inducing inflammation
- (2016) Lei Zhang et al. Scientific Reports
- Novel Phage Lysin Capable of Killing the Multidrug-Resistant Gram-Negative Bacterium Acinetobacter baumannii in a Mouse Bacteremia Model
- (2015) Rolf Lood et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
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- (2015) Fang Tang et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Combination Therapy of LysGH15 and Apigenin as a New Strategy for Treating Pneumonia Caused by Staphylococcus aureus
- (2015) Feifei Xia et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- EC300: a phage-based, bacteriolysin-like protein with enhanced antibacterial activity against Enterococcus faecalis
- (2015) Daniela Proença et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Breaking barriers: expansion of the use of endolysins as novel antibacterials against Gram-negative bacteria
- (2015) Yves Briers et al. Future Microbiology
- A novel chimeric phage lysin with high in vitro and in vivo bactericidal activity against Streptococcus pneumoniae
- (2015) R. Diez-Martinez et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Evolutionarily distinct bacteriophage endolysins featuring conserved peptidoglycan cleavage sites protect mice from MRSA infection
- (2015) Mathias Schmelcher et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Antibacterial Activity of a Novel Peptide-Modified Lysin Against Acinetobacter baumannii and Pseudomonas aeruginosa
- (2015) Hang Yang et al. Frontiers in Microbiology
- A chimeolysin with extended-spectrum streptococcal host range found by an induced lysis-based rapid screening method
- (2015) Hang Yang et al. Scientific Reports
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- (2014) Yves Briers et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Intravitreal Injection of the Chimeric Phage Endolysin Ply187 Protects Mice from Staphylococcus aureus Endophthalmitis
- (2014) Pawan Kumar Singh et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- A Highly Active and Negatively Charged Streptococcus pyogenes Lysin with a Rare d-Alanyl-l-Alanine Endopeptidase Activity Protects Mice against Streptococcal Bacteremia
- (2014) Rolf Lood et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Multistate Point-Prevalence Survey of Health Care–Associated Infections
- (2014) Shelley S. Magill et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Thermostable Salmonella Phage Endolysin, Lys68, with Broad Bactericidal Properties against Gram-Negative Pathogens in Presence of Weak Acids
- (2014) Hugo Oliveira et al. PLoS One
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- (2014) Y. Briers et al. mBio
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- (2012) Kimberly M. Payne et al. PLoS One
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- (2012) Maarten Walmagh et al. PLoS One
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- (2012) Hugo Oliveira et al. TRENDS IN FOOD SCIENCE & TECHNOLOGY
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- (2011) Meng-Jiun Lai et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
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- (2011) Lieh Yoon Low et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2011) Athanasios Typas et al. NATURE REVIEWS MICROBIOLOGY
- Domain shuffling and module engineering of Listeria phage endolysins for enhanced lytic activity and binding affinity
- (2011) Mathias Schmelcher et al. Microbial Biotechnology
- Synergism between a Novel Chimeric Lysin and Oxacillin Protects against Infection by Methicillin-Resistant Staphylococcus aureus
- (2010) A. Daniel et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- A Novel Chimeric Lysin Shows Superiority to Mupirocin for Skin Decolonization of Methicillin-Resistant and -SensitiveStaphylococcus aureusStrains
- (2010) Mina Pastagia et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Bacteriophage endolysins: A novel anti-infective to control Gram-positive pathogens
- (2010) Vincent A. Fischetti INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
- LysGH15, a Novel Bacteriophage Lysin, Protects a Murine Bacteremia Model Efficiently against Lethal Methicillin-Resistant Staphylococcus aureus Infection
- (2010) J. Gu et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Antibacterial Efficacy of Phages against Pseudomonas aeruginosa Infections in Mice and Drosophila melanogaster
- (2009) Y.-J. Heo et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Systemic use of the endolysin Cpl-1 rescues mice with fatal pneumococcal pneumonia*
- (2009) Martin Witzenrath et al. CRITICAL CARE MEDICINE
- LysK CHAP endopeptidase domain is required for lysis of live staphylococcal cells
- (2009) Stephen C. Becker et al. FEMS MICROBIOLOGY LETTERS
- Shared Catalysis in Virus Entry and Bacterial Cell Wall Depolymerization
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- (2008) M. Horgan et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
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- (2008) Yves Briers et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2008) Salim Manoharadas et al. JOURNAL OF BIOTECHNOLOGY
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