Effect of smoking on gene expression profile – overall mechanism, impact on respiratory system function, and reference to electronic cigarettes

Gene and metabolite time-course response to cigarette smoking in mouse lung and plasma

(2017) Mikaela A. Miller et al.   PLoS One

MicroRNA expression profiling defines the impact of electronic cigarettes on human airway epithelial cells

(2017) Siva Kumar Solleti et al.   Scientific Reports

Gene expression profiling of epigenetic chromatin modification enzymes and histone marks by cigarette smoke: implications for COPD and lung cancer

(2016) Isaac K. Sundar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

E-cigarette use results in suppression of immune and inflammatory-response genes in nasal epithelial cells similar to cigarette smoke

(2016) Elizabeth M. Martin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Chemical Composition of Aerosol from an E-Cigarette: A Quantitative Comparison with Cigarette Smoke

(2016) Jennifer Margham et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Cigarette Smoke-Induced Hypermethylation of the GCLC Gene Is Associated With COPD

(2016) Linling Cheng et al.   CHEST

Epigenetic Signatures of Cigarette SmokingCLINICAL PERSPECTIVE

(2016) Roby Joehanes et al.   Circulation-Cardiovascular Genetics

Genome-Wide Analysis of DNA Methylation and Cigarette Smoking in a Chinese Population

(2016) Xiaoyan Zhu et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Cigarette smoke extract-induced interleukin-6 expression is regulated by phospholipase D1 in human bronchial epithelial cells

(2016) Jun Bon Koo et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

The Effect of Different Case Definitions of Current Smoking on the Discovery of Smoking-Related Blood Gene Expression Signatures in Chronic Obstructive Pulmonary Disease

(2016) Ma’en Obeidat et al.   NICOTINE & TOBACCO RESEARCH

Repair Pathway Choices and Consequences at the Double-Strand Break

(2016) Raphael Ceccaldi et al.   TRENDS IN CELL BIOLOGY

Transcriptome sequencing reveals e-cigarette vapor and mainstream-smoke from tobacco cigarettes activate different gene expression profiles in human bronchial epithelial cells

(2016) Yifei Shen et al.   Scientific Reports

Frontal Cortex Transcriptome Analysis of Mice Exposed to Electronic Cigarettes During Early Life Stages

(2016) Dana Lauterstein et al.   International Journal of Environmental Research and Public Health

Epigenetic Signatures of Cigarette SmokingCLINICAL PERSPECTIVE

(2016) Roby Joehanes et al.   Circulation-Cardiovascular Genetics

DNA methylation and smoking in Korean adults: epigenome-wide association study

(2016) Mi Kyeong Lee et al.   Clinical Epigenetics

Time course of cigarette smoke-induced changes of systemic inflammation and muscle structure

(2015) K. Krüger et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Identification of time-dependent biomarkers and effects of exposure to volatile organic compounds using high-throughput analysis

(2015) Ji Young Hong et al.   ENVIRONMENTAL TOXICOLOGY

Characterisation of mainstream and passive vapours emitted by selected electronic cigarettes

(2015) Otmar Geiss et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Excess placental secreted frizzled-related protein 1 in maternal smokers impairs fetal growth

(2015) Alice Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

A varying T cell subtype explains apparent tobacco smoking induced single CpG hypomethylation in whole blood

(2015) Mario Bauer et al.   Clinical Epigenetics

In vitro effects of low-level aldehyde exposures on human umbilical vein endothelial cells

(2015) Nuan P. Cheah et al.   Toxicology Research

Exposure to Electronic Cigarettes Impairs Pulmonary Anti-Bacterial and Anti-Viral Defenses in a Mouse Model

(2015) Thomas E. Sussan et al.   PLoS One

Activation of the aryl hydrocarbon receptor by carcinogenic aromatic amines and modulatory effects of their N-acetylated metabolites

(2014) Ludmila Juricek et al.   ARCHIVES OF TOXICOLOGY

Maternal Smoking and Placental Expression of a Panel of Genes Related to Angiogenesis and Oxidative Stress in Early Pregnancy

(2014) Azusa Shinjo et al.   FETAL DIAGNOSIS AND THERAPY

A 28-day rat inhalation study with an integrated molecular toxicology endpoint demonstrates reduced exposure effects for a prototypic modified risk tobacco product compared with conventional cigarettes

(2014) Ulrike Kogel et al.   FOOD AND CHEMICAL TOXICOLOGY

Smoking Dysregulates the Human Airway Basal Cell Transcriptome at COPD Risk Locus 19q13.2

(2014) Dorothy M. Ryan et al.   PLoS One

Effects of Maternal Smoking on the Placental Expression of Genes Related to Angiogenesis and Apoptosis during the First Trimester

(2014) Akihiro Kawashima et al.   PLoS One

Effects of Smoking Cessation on Gene Expression in Human Leukocytes of Chronic Smoker

(2014) Soo-Jeong Kim et al.   Psychiatry Investigation

The composition of cigarette smoke determines inflammatory cell recruitment to the lung in COPD mouse models

(2013) Gerrit John et al.   CLINICAL SCIENCE

DNA Methylation as a Long-term Biomarker of Exposure to Tobacco Smoke

(2013) Natalie S. Shenker et al.   EPIDEMIOLOGY

Cigarette smoking induces small airway epithelial epigenetic changes with corresponding modulation of gene expression

(2013) Lauren J. Buro-Auriemma et al.   HUMAN MOLECULAR GENETICS

Cigarette Smoke Induces Distinct Histone Modifications in Lung Cells: Implications for the Pathogenesis of COPD and Lung Cancer

(2013) Isaac K. Sundar et al.   JOURNAL OF PROTEOME RESEARCH

Tobacco Smoking Leads to Extensive Genome-Wide Changes in DNA Methylation

(2013) Sonja Zeilinger et al.   PLoS One

Cigarette smoke induces molecular responses in respiratory tissues of ApoE−/− mice that are progressively deactivated upon cessation

(2013) Stéphanie Boué et al.   TOXICOLOGY

In vitro effects of aldehydes present in tobacco smoke on gene expression in human lung alveolar epithelial cells

(2013) Nuan P. Cheah et al.   TOXICOLOGY IN VITRO

Coordinated changes in AHRR methylation in lymphoblasts and pulmonary macrophages from smokers

(2012) Martha M. Monick et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Cigarette smoking behaviors and time since quitting are associated with differential DNA methylation across the human genome

(2012) Emily S. Wan et al.   HUMAN MOLECULAR GENETICS

Cigarette Smoke Induces MUC5AC Protein Expression through the Activation of Sp1

(2012) Y. Peter Di et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coordinated DNA methylation and gene expression changes in smoker alveolar macrophages: specific effects on VEGF receptor 1 expression

(2012) R. A. Philibert et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Inflammatory Transcriptome Profiling of Human Monocytes Exposed Acutely to Cigarette Smoke

(2012) William R. Wright et al.   PLoS One

Circulating miRNAs might be promising biomarkers to reflect the dynamic pathological changes in smoking-related interstitial fibrosis

(2012) Huang Yuchuan et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Cross experimental analysis of microarray gene expression data from volatile organic compounds treated targets

(2011) Won Cheol Yim et al.   Molecular & Cellular Toxicology

Hypoxia Induces Genomic DNA Demethylation through the Activation of HIF-1  and Transcriptional Upregulation of MAT2A in Hepatoma Cells

(2011) Q. Liu et al.   MOLECULAR CANCER THERAPEUTICS

Protein kinase CK2-mediated phosphorylation of HDAC2 regulates co-repressor formation, deacetylase activity and acetylation of HDAC2 by cigarette smoke and aldehydes

(2010) David Adenuga et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Transcriptomic epidemiology of smoking: the effect of smoking on gene expression in lymphocytes

(2010) Jac C Charlesworth et al.   BMC Medical Genomics

Effects of Cigarette Smoke on the Human Oral Mucosal Transcriptome

(2010) J. O. Boyle et al.   Cancer Prevention Research

Cigarette smoking reprograms apical junctional complex molecular architecture in the human airway epithelium in vivo

(2010) Renat Shaykhiev et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Nicotine Addiction

(2010) Neal L. Benowitz   NEW ENGLAND JOURNAL OF MEDICINE

Similar gene expression profiles in smokers and patients with moderate COPD

(2010) Laia Llinàs et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Pathophysiological Impact of Cigarette Smoke Exposure on the Cerebrovascular System with a Focus on the Blood-brain Barrier: Expanding the Awareness of Smoking Toxicity in an Underappreciated Area

(2010) Peter Mazzone et al.   International Journal of Environmental Research and Public Health

Nicotinic acetylcholine receptor-mediated calcium signaling in the nervous system

(2009) Jian-xin Shen et al.   ACTA PHARMACOLOGICA SINICA

Cigarette smoke-induced emphysema in A/J mice is associated with pulmonary oxidative stress, apoptosis of lung cells, and global alterations in gene expression

(2009) Tirumalai Rangasamy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Trachea Epithelium as a “Canary” for Cigarette Smoking-Induced Biologic Phenotype of the Small Airway Epithelium

(2009) Meredith L. Turetz et al.   CTS-Clinical and Translational Science

Protein Kinase Cζ Mediates Cigarette Smoke/Aldehyde- and Lipopolysaccharide-induced Lung Inflammation and Histone Modifications

(2009) Hongwei Yao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nicotine modulates bone metabolism-associated gene expression in osteoblast cells

(2009) David E. Rothem et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Cigarette Smoke Condensate Causes a Decrease of the Gene Expression of Cu–Zn Superoxide Dismutase, Mn Superoxide Dismutase, Glutathione Peroxidase, Catalase, and Free Radical-Induced Cell Injury in SH-SY5Y Human Neuroblastoma Cells

(2009) Michela Russo et al.   NEUROTOXICITY RESEARCH

Down-regulation of the Notch Pathway in Human Airway Epithelium in Association with Smoking and Chronic Obstructive Pulmonary Disease

(2008) Ann E. Tilley et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Oral Epithelium as a Surrogate Tissue for Assessing Smoking-Induced Molecular Alterations in the Lungs

(2008) Manisha Bhutani et al.   Cancer Prevention Research

Variability in Small Airway Epithelial Gene Expression Among Normal Smokers

(2008) Zeinab Ammous et al.   CHEST

Carbon monoxide, reactive oxygen signaling, and oxidative stress

(2008) Claude A. Piantadosi   FREE RADICAL BIOLOGY AND MEDICINE

Nicotine decreases DNA methyltransferase 1 expression and glutamic acid decarboxylase 67 promoter methylation in GABAergic interneurons

(2008) R. Satta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA