Calix[4]arene containing thiourea and coumarin functionality as highly selective fluorescent and colorimetric chemosensor for fluoride ion

A novel calix[4]arene based chemosensor L which contains coumarin and thiourea group has been synthesized and characterized. Interestingly, probe L exhibits both fluorescent and colorimetric response to fluoride anion with high selectivity and sensitivity. The addition of F- to a solution of probe L resulted in obvious naked-eye color change from colorless to orange under daylight and prominent fluorescence quenching. Further studies showed that the recognition process was less affected by other anions. The binding property of L with F- was studied by a combination of combination of various spectroscopic techniques, such as absorption spectra, fluorescence titration, Job's plot and H-1 NMR titration. We are anticipating that this architecture with functional group attached to upper rim of calix[4]arene platform may provide a new approach for the development of F- chemosensor. (C) 2018 Elsevier B.V. All rights reserved.