Selective CXCR4+ Cancer Cell Targeting and Potent Antineoplastic Effect by a Nanostructured Version of Recombinant Ricin

Self-assembling toxin-based nanoparticles as self-delivered antitumoral drugs

(2018) Laura Sánchez-García et al.   JOURNAL OF CONTROLLED RELEASE

Protein-Based Therapeutic Killing for Cancer Therapies

(2018) Naroa Serna et al.   TRENDS IN BIOTECHNOLOGY

Immunotoxins in cancer therapy: Review and update

(2017) Bahman Akbari et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Taking the vehicle out of drug delivery

(2017) Jianliang Shen et al.   Materials Today

Intrinsic functional and architectonic heterogeneity of tumor-targeted protein nanoparticles

(2017) Mireia Pesarrodona et al.   Nanoscale

Protein and Peptide Biopharmaceuticals: An Overview

(2017) Dominic Agyei et al.   PROTEIN AND PEPTIDE LETTERS

Drug-induced hepatotoxicity in cancer patients - implication for treatment

(2016) Bruno Vincenzi et al.   Expert Opinion On Drug Safety

Antitumor effect of CXCR4 antagonist AMD3100 on the tumorigenic cell line of BHP10-3 papillary thyroid cancer cells

(2016) Young Ho Jung et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Recombinant pharmaceuticals from microbial cells: a 2015 update

(2016) Laura Sanchez-Garcia et al.   Microbial Cell Factories

Functional recruitment for drug delivery through protein-based nanotechnologies

(2016) Esther Vazquez et al.   Nanomedicine

Cancer-specific uptake of a liganded protein nanocarrier targeting aggressive CXCR4 + colorectal cancer models

(2016) María Virtudes Céspedes et al.   Nanomedicine-Nanotechnology Biology and Medicine

Engineering tumor cell targeting in nanoscale amyloidal materials

(2016) Ugutz Unzueta et al.   NANOTECHNOLOGY

Cellular uptake and intracellular fate of protein releasing bacterial amyloids in mammalian cells

(2016) Joaquin Seras-Franzoso et al.   Soft Matter

Emerging Strategies for Developing Next-Generation Protein Therapeutics for Cancer Treatment

(2016) James R. Kintzing et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Analysis of nanoparticle delivery to tumours

(2016) Stefan Wilhelm et al.   Nature Reviews Materials

Bacterial mimetics of endocrine secretory granules as immobilized in vivo depots for functional protein drugs

(2016) María Virtudes Céspedes et al.   Scientific Reports

Bottom-Up Instructive Quality Control in the Biofabrication of Smart Protein Materials

(2015) Fabián Rueda et al.   ADVANCED MATERIALS

Immunoconjugates in the management of hairy cell leukemia

(2015) Robert J. Kreitman et al.   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

CXCR4 and CXCL12 Expression in Rectal Tumors of Stage IV Patients Before and After Local Radiotherapy and Systemic Neoadjuvant Treatment

(2015) Karin Tamas et al.   CURRENT PHARMACEUTICAL DESIGN

In vivo molecular imaging of chemokine receptor CXCR4 expression in patients with advanced multiple myeloma

(2015) K. Philipp-Abbrederis et al.   EMBO Molecular Medicine

Advances in Anticancer Immunotoxin Therapy

(2015) C. Alewine et al.   ONCOLOGIST

Towards protein-based viral mimetics for cancer therapies

(2015) Ugutz Unzueta et al.   TRENDS IN BIOTECHNOLOGY

Potential therapeutic applications of plant toxin-ricin in cancer: challenges and advances

(2015) Nikhil Tyagi et al.   TUMOR BIOLOGY

Phase 1 study of the antimesothelin immunotoxin SS1P in combination with pemetrexed and cisplatin for front-line therapy of pleural mesothelioma and correlation of tumor response with serum mesothelin, megakaryocyte potentiating factor, and cancer antigen

(2014) Raffit Hassan et al.   CANCER

Targeting Chemokine Receptor CXCR4 for Treatment of HIV-1 Infection, Tumor Progression, and Metastasis

(2014) Won-Tak Choi et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

CXCR4 Expression and Treatment with SDF-1α or Plerixafor Modulate Proliferation and Chemosensitivity of Colon Cancer Cells

(2014) Doreen Heckmann et al.   Translational Oncology

Exploiting nanotechnology to overcome tumor drug resistance: Challenges and opportunities

(2013) Ameya R. Kirtane et al.   ADVANCED DRUG DELIVERY REVIEWS

Non-amyloidogenic peptide tags for the regulatable self-assembling of protein-only nanoparticles

(2012) Ugutz Unzueta et al.   BIOMATERIALS

Differential Effects of Denileukin Diftitox IL-2 Immunotoxin on NK and Regulatory T Cells in Nonhuman Primates

(2012) Y. Yamada et al.   JOURNAL OF IMMUNOLOGY

Nanomedicine(s) under the Microscope

(2011) Ruth Duncan et al.   MOLECULAR PHARMACEUTICS

Denileukin diftitox: a novel immunotoxin

(2009) George Manoukian et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Genetic alteration of a bispecific ligand-directed toxin targeting human CD19 and CD22 receptors resulting in improved efficacy against systemic B cell malignancy

(2009) Daniel A. Vallera et al.   LEUKEMIA RESEARCH