Article
Chemistry, Analytical
Yulan Tian, Ping Zhu, Yating Chen, Xiaoyu Bai, Liping Du, Wei Chen, Chunsheng Wu, Ping Wang
Summary: In this study, a novel piezoelectric aptasensor was designed for the detection of OA, with aptamers and quartz crystal microbalance used for signal detection, and gold nanoparticles for signal amplification. The biosensor showed a wide linear detection range and low detection limit.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Applied
Reza Mahjub, Omid Heydari Shayesteh, Katayoun Derakhshandeh, Akram Ranjbar, Fereshteh Mehri, Ali Heshmati
Summary: In this study, a novel colorimetric bioassay method was developed for the sensitive determination of tobramycin. The method utilizes aptamers and silver nanoparticles to induce aggregation and visible color change in the presence of tobramycin, allowing for quantitative analysis. This method offers high sensitivity and visual detection.
Article
Chemistry, Analytical
Jing Qian, Yue Liu, Haining Cui, Huiyuan Yang, Mustafa Hussain, Kun Wang, Jie Wei, Lingliang Long, Lijun Ding, Chengquan Wang
Summary: A disposable aptasensing chip has been developed for simultaneous label-free detection of four coexisting toxins in food, showing characteristics of simplicity, easy operation, and multiple toxin recognition.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Mingdi Jia, Licheng Yu, Xiaoxuan Li, Yijun Li, Xiwen He, Langxing Chen, Yukui Zhang
Summary: As a novel optical responsive material, photonic crystal shows great potential in the recognition and detection of small molecules. In this study, a label-free composite sensor for aflatoxin B1 (AFB1) based on aptamer-functionalized photonic crystal arrays was successfully developed. The sensing system demonstrated a good linearity and ultrasensitive detection to AFB1, with a wide detection range and a low limit of detection.
Article
Chemistry, Applied
Xiaoxuan Li, Mingdi Jia, Licheng Yu, Yijun Li, Xiwen He, Langxing Chen, Yukui Zhang
Summary: In this study, a novel photonic crystal aptamer biosensor was successfully manufactured, which demonstrated label-free and highly sensitive detection of kanamycin. The biosensor utilized the localized surface plasmon resonance effect of Au NPs and optical response capability of PC to achieve excellent performance in the detection of KANA in complex conditions.
Article
Chemistry, Analytical
Huilin Gao, Yongchang Bai, Baixun He, Cherie S. Tan
Summary: In this study, a label-free functionalized aptamer sensor attached to an electrode with gold nanoparticles and carboxylated graphene oxide was used to measure C-reactive protein (CRP) levels. The adapted sensor showed a broad linear range, superior stability, specificity, and reproducibility, making it suitable for complex applications with interfering substances.
Article
Biochemistry & Molecular Biology
Fatemeh Shafiei, Reyhaneh Sadat Saberi, Masoud A. Mehrgardi
Summary: The study developed a graphene-based aptasensor for sensitive detection of human breast cancer cells, showing high selectivity and sensitivity. The aptamer played a key role in improving the properties of the composite for cell capture.
BIOELECTROCHEMISTRY
(2021)
Article
Chemistry, Physical
Shringika Soni, Utkarsh Jain, Donald H. Burke, Nidhi Chauhan
Summary: Prescription stimulant drug (PSD) abuse is a global concern, and there is a need for the development of sensitive, rapid, and low-cost kits for on-spot PSD detection. In this study, a gold nanoflower modified, electrochemical aptasensor was successfully developed for Amphetamine (AMP) detection. The aptasensor showed high sensitivity, low limit of detection, and negligible interference from potentially interfering compounds. It was able to accurately detect AMP in spiked urine and water samples.
SURFACES AND INTERFACES
(2022)
Article
Chemistry, Organic
Hao Zhang, Xin Wang, Kun-Tao Huang, Feng Liang, Ying-Wei Yang
Summary: A facile synthesis strategy was developed for the preparation of carboxylated leaning tower[6]arene (CLT6)-mediated gold nanoparticles (CLT6-AuNPs) without external energy sources and reducing agents. The CLT6-AuNPs, with controllable particle size due to the cavity structure of CLT6, exhibited good stability and excellent performance in label-free detection of diquat. The reduction mechanism of AuNP formation was revealed to involve the cleavage of some phenyl ether bonds of CLT6 to produce reductive phenols and reduce Au3+ to AuNPs.
Article
Chemistry, Analytical
Mahsa Zamani, Mehrab Pourmadadi, S. A. Seyyed Ebrahimi, Fatemeh Yazdian, Javad Shabani Shayeh
Summary: The study focused on dual electrochemical detection of endotoxin using a magnetic graphene-based nanocomposite modified with thiourea and amino-modified aptamers. Various characterization methods were employed to study nanomaterials, while electrochemical techniques were used to study the electrochemical properties of the aptasensor. Both labeled and label-free electrochemical detection of endotoxin were performed, showing high sensitivity and specificity towards LPS.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Biochemical Research Methods
Rosaceleste Zumpano, Manuela Manghisi, Francesca Polli, Cristine D'Agostino, Federica Ietto, Gabriele Favero, Franco Mazzei
Summary: This study developed a label-free electrochemical immunosensor for the quick, cheap, and straightforward determination of atrazine, achieving detection through a technological platform and specific treatment methods. Under optimal experimental conditions, the immunosensor exhibited good linearity range, limit of detection, reproducibility, and stability, making it suitable for successful application in the detection and monitoring of atrazine in real water samples.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Li Li, Zhengbo Chen
Summary: In this study, a high specificity, flexibility, and simplicity aptasensor strategy was designed using a triblock DNA probe. It was found that the polyA fragment could assemble on the gold electrode surface via polyA instead of traditional Au-S bonds, leading to improved hybridization stability. The electrochemical aptasensor showed good repeatability, stability, and specificity.
BIOELECTROCHEMISTRY
(2023)
Article
Chemistry, Analytical
Pengfei Ma, Hualin Guo, Nuo Duan, Xiaoyuan Ma, Lin Yue, Qianhui Gu, Zhouping Wang
Summary: The study showed that ionic strength and type influence the recognition of aptamers, with magnesium ion playing a vital role in the binding process. Various methods were used to analyze the binding performance and conformational changes of the aptamer, leading to the development of a label-free fluorescence polarization sensor for detecting chloramphenicol.
Article
Chemistry, Analytical
Qianqian Kong, Fengling Yue, Mengyue Liu, Jingcheng Huang, Fengzhen Yang, Junjie Liu, Jiansen Li, Falan Li, Xia Sun, Yemin Guo, Yelong Zhu
Summary: In this study, aptamers with high affinity for TMX were obtained through GO-SELEX and further truncated to improve their affinity. The truncated aptamers showed better sensitivity in TMX detection, and their feasibility in vegetable samples was preliminarily verified.
ANALYTICA CHIMICA ACTA
(2022)
Article
Spectroscopy
Lei Liao, Jianglong Yao, Ruo Yuan, Yun Xiang, Bingying Jiang
Summary: In this study, a fluorescence strategy based on transcriptional amplification of lighting-up aptamers was developed for label-free, low background and sensitive monitoring of FEN1, with a low detection limit, allowing for early-stage cancer diagnosis.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Engineering, Chemical
Wuyuan Liu, Zihan Gao, Ming Sun, Jiajian Gao, Lifeng Wang, Xiangyun Zhao, Runnong Yang, Lin Yu
Summary: A series of Cr alpha Mn beta CeTiOx catalysts were prepared using one-pot precipitation method and evaluated for the selective catalytic reduction of NO with ammonia. Among the catalysts prepared, the Cr0.006Mn0.05CeTiOx catalyst exhibited the highest low-temperature activity and widest activity window, as well as outstanding sulfur resistance. The amorphous catalyst had a larger specific surface area, high ammonia adsorption, and strong acidity, resulting in improved catalytic activity. The synergetic effect of Cr and Mn inhibited the accumulation of hydrogen sulfate or sulfate considerably.
CHEMICAL ENGINEERING SCIENCE
(2022)
Article
Chemistry, Physical
Wenjing Cheng, Taoyan Mao, Runnong Yang, Shengbo Han, Ming Sun, Gao Cheng, Yuanhong Zhong, Lin Yu
Summary: Bola polyhydroxy silicone quaternary ammonium (BPSQA) was synthesized and characterized in this study. The results showed that BPSQA had excellent stability and vesica morphology, and could make the surface of cotton fabric smooth. At a specific molar ratio, the maximum zeta potential of BPSQA in water was achieved, resulting in better colorfastness, durability, and UV irradiation fastness of the dyed cotton fabric compared to propyl-propane thiosulfonate (PTSO).
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Chemistry, Physical
Gao Cheng, Peng Liu, Shihong Chen, Yanxue Wu, Leheng Huang, Meijie Chen, Chengjun Hu, Bang Lan, Xiaohui Su, Ming Sun, Lin Yu
Summary: In this study, hierarchical hollow beta-MnO2 microspheres assembled by nanorod subunits were successfully fabricated using a one-step hydrothermal approach. The reaction temperature and H2SO4 concentration were found to influence the crystalline phase and morphology of the products. The hollow beta-MnO2 microspheres were formed through a self-templated process by phase transformation. Compared with commercial beta-MnO2 particles, the hollow microspheres exhibited superior ORR performance.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Electrochemistry
Shengbo Han, Shaomin Peng, Zihan Gao, Ming Sun, Gao Cheng, Hao Zhang, Xiaohui Su, Meijie Chen, Lin Yu
Summary: This study presents a simple and scalable green strategy to convert waste biomass materials into N-doped carbon materials with excellent ORR ability, providing a practical solution to improve the ORR performance of ZAB.
ELECTROCHIMICA ACTA
(2022)
Article
Energy & Fuels
Liurui Bao, Shanhui Zhu, Yi Chen, Yu Wang, Wenhao Meng, Shuai Xu, Zehui Lin, Xingyun Li, Ming Sun, Limin Guo
Summary: The development of advanced metal oxide catalysts for VOCs abatement is crucial for environmental and economic reasons. In this study, a defective Co3O4 catalyst is created through N doping, resulting in improved oxygen mobility and increased active surface oxygen. The N-doped Co3O4 catalyst exhibited excellent toluene oxidation performance and maintained high hydrothermal stability.
Article
Chemistry, Physical
Qixing Xie, Gao Cheng, Tong Xue, Leheng Huang, Shihong Chen, Yue Sun, Ming Sun, Haozhi Wang, Lin Yu
Summary: This study investigates the effect of alkali cations on the electrochemical behavior and charge storage mechanism of delta-MnO2 cathode in aqueous zinc-ion batteries. Preintercalating various alkali cations into delta-MnO2 nanosheets enhances the cycling stability, rate capability, and reversibility. The increase in pre-intercalated ion radius improves the performance.
MATERIALS TODAY ENERGY
(2022)
Article
Engineering, Chemical
Wuyuan Liu, Zhaoying Wang, Ming Sun, Jiajian Gao, Lifeng Wang, Zihan Gao, Yingying Xu, Xiangyun Zhao, Cheng Zhang, Lin Yu
Summary: CeO2 modified Cu-SSZ-13 monolith catalysts were prepared using the solvent combustion method, and the Ce2Cu-SSZ-13 catalyst showed excellent activity, stability and resistance in NH3-SCR of NO. The modification of CeO2 enhanced the acidity, redox capacity and ammonia adsorption capacity, leading to the high performance of Ce2Cu-SSZ-13 catalyst. In addition, the porous structure generated via solvent combustion increased the diffusion rate of reaction and the introduction of CeO2 promoted the oxidation of NO to NO2, resulting in fast SCR reaction.
Article
Electrochemistry
Kangdi Lin, Zihao Zhou, Chenting Peng, Jinlian Zhang, Hongyun Huang, Meijie Chen, Ming Sun, Lin Yu
Summary: Solid-state zinc-air batteries (ZABs) are a promising choice for next-generation energy storage devices in AI and wearable technology. However, the unsatisfactory catalytic performance and poor contact with electrolytes hinder their effectiveness. This study presents a bifunctional catalyst (oxygen reduction and evolution reactions) composed of NiCo layered double hydroxide@NiCo2S4 with well-designed heterointerfaces, enhancing electronic interaction and optimizing energy-level configuration. The catalyst exhibits fast charge transfer kinetics and enhanced activity, leading to excellent power density of 88.4 mW cm-2 and high round-trip efficiency of 74.3% in solid-state ZABs. This work provides valuable insights into the structure-activity relationship for high-performance ZABs using heterostructure catalysts.
ELECTROCHIMICA ACTA
(2023)
Article
Chemistry, Physical
Yingxia Zhao, Qunlei Wen, Danji Huang, Chi Jiao, Youwen Liu, Yan Liu, Jiakun Fang, Ming Sun, Lin Yu
Summary: Guided by density functional theory, the interaction of cation vacancies and dopants can manipulate d band centers, thus achieving near-optimal binding energies of the oxygenated intermediates and ultralow potentials. This principle is implemented experimentally by catalysis operando variations synthesis, where Mo leaching from high-entropy Co, Mo co-doped NiFe hydroxide precursors forms Co dopant and cation vacancy coexistent NiFe oxyhydroxide. Operando electrochemical spectroscopy reveals that dual-cation-defects promote the easier oxidation transition of metal sites, contributing to a low overpotential of 255 mV at 100 mA cm(-2). Furthermore, dual-regulated NiFe oxyhydroxide electrodes operate stably at 8 A in practical industrial electrolyzers with an ultralow energy consumption of approximately 4.6 kWh m(-3) H-2, verifying the feasibility of lab-constructed novel catalysts towards industrialization.
ADVANCED ENERGY MATERIALS
(2023)
Article
Engineering, Chemical
Shengbo Han, Ying Wu, Shaomin Peng, Yingying Xu, Ming Sun, Xiaohui Su, Yuanhong Zhong, Hongli Wen, Jun He, Lin Yu
Summary: Through experimentation and simulation, it was found that an appropriate forced convection intensity can significantly improve the power density of Zn-air batteries by more efficiently utilizing gas-O2 molecules. This research provides a long-term opportunity to improve the electrochemical performance and broaden the application scenarios of Zn-air batteries.
CHEMICAL ENGINEERING SCIENCE
(2023)
Article
Engineering, Chemical
Zihan Gao, Runnong Yang, Zhaoying Wang, Wuyuan Liu, Ming Sun, Cheng Zhang, Lin Yu
Summary: In this study, the challenges of low selectivity and inadequate catalytic performance of manganese oxides in medium and high-temperature SCR reactions were effectively addressed by using manganese-based ternary catalysts Fe-Mn/Ce. The Fe-Mn/Ce catalysts exhibited excellent catalytic performance, with NO x conversions exceeding 90% over a wide operating temperature range (164.5-419.4 degrees C) and high N-2 selectivity. Further research revealed that higher proportions of Fe2+ and Mn4+ in the Fe-Mn/Ce catalysts with abundant redox sites and surface acidity were important factors for promoting excellent SCR reactivity. Additionally, the modification with Fe facilitated effective electron transfer, reducing the pathway of N2O generation and increasing catalytic reaction sites, thereby enhancing overall catalytic performance.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2023)
Article
Chemistry, Physical
Hua Yang, Zihao Zhou, Huijuan Yu, Hongli Wen, Runnong Yang, Shaomin Peng, Ming Sun, Lin Yu
Summary: Efficient and economic bifunctional electrocatalyst for water splitting to produce hydrogen is urgently required. Layered double hydroxides (LDHs) are effective for oxygen evolution reaction (OER) but show challenging hydrogen evolution reaction (HER) activity. A hydrothermal-treatment strategy enhances the HER and OER performance of NiCo-LDH by creating metal vacancies and forming Ni/Co(OH)2 phase, tuning electronic structure, and improving electrical conductivity. The resulting NiCo-LDH-OH catalyst exhibits significantly reduced overpotentials for both HER and OER, and demonstrates superior activity for overall water splitting with no decay after 20 hours. This work paves a new path for efficient LDHs-based HER/OER bifunctional catalysts.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Chemistry, Physical
Kangdi Lin, Zihao Zhou, Ben Ma, Yingru Chen, Kai Yan, Bentian Zhang, Ying Wu, Ming Sun, Lin Yu
Summary: Researchers prepared NiCo nanoalloy@NC samples with tunable electronic structures, among which Ni2Co4@NC showed a suitable electronic structure for promoting oxygen reduction and evolution reactions, demonstrating excellent stability and reaction kinetics. Through experiments and theoretical simulations, the reconstruction behavior of these nanoalloys@NC samples and their crucial role in electrochemical kinetics were revealed.
ACS APPLIED ENERGY MATERIALS
(2023)
Article
Engineering, Chemical
Sijie Liu, Wenjing Dai, Biyuan Liu, Suxuan Lin, Feng Zeng, Qingxia Huang, Ming Sun, Fada Feng, Bang Lan, Haibao Huang
Summary: Ozone pollution has long been a threat to human health and ecosystems. Researchers have synthesized hexagonal birnessites with varying degrees of c-disordering and found that the highly disordered birnessite (HDB) with the highest content of oxygen vacancies (V-O) demonstrated the superior catalytic activity. The HDB maintained a high O-3 conversion efficiency even after 24 hours of reaction at a high space velocity and under high humidity. The stability of HDB was attributed to the presence of stable out-of-layer V-O which facilitated the desorption of intermediate O-2(2-) and reduced the competitive adsorption of H2O.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Leliang Cao, Jie Huang, Xueying Wu, Ben Ma, Qingqing Xu, Yuanhong Zhong, Ying Wu, Ming Sun, Lin Yu
Summary: In this study, a bismuth-terephthalate framework material was synthesized and found to exhibit excellent formate production activity, selectivity, and durability. Density functional theory calculations also revealed the mechanism of its optimized structure in the electrocatalytic production of formate from CO2.
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)