The impact of multi-walled carbon nanotubes (MWCNTs) on macrophages: contribution of MWCNT characteristics

Multi-walled carbon nanotubes act as a chemokine and recruit macrophages by activating the PLC/IP3/CRAC channel signaling pathway

(2017) Hui Li et al.   Scientific Reports

Intracellular degradation of chemically functionalized carbon nanotubes using a long-term primary microglial culture model

(2016) Cyrill Bussy et al.   Nanoscale

Carbon Nanotubes Activate Macrophages into a M1/M2 Mixed Status: Recruiting Naïve Macrophages and Supporting Angiogenesis

(2015) Jie Meng et al.   ACS Applied Materials & Interfaces

Carbon Nanotube Degradation in Macrophages: Live Nanoscale Monitoring and Understanding of Biological Pathway

(2015) Dan Elgrabli et al.   ACS Nano

High resolution and dynamic imaging of biopersistence and bioreactivity of extra and intracellular MWNTs exposed to microglial cells

(2015) Angela E. Goode et al.   BIOMATERIALS

Asbestos and multi-walled carbon nanotubes generate distinct oxidative responses in inflammatory cells

(2015) Satomi Funahashi et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Surface modification of multiwall carbon nanotubes determines the pro-inflammatory outcome in macrophage

(2015) Ting Zhang et al.   JOURNAL OF HAZARDOUS MATERIALS

Innate immune humoral factors, C1q and factor H, with differential pattern recognition properties, alter macrophage response to carbon nanotubes

(2015) Kirsten M. Pondman et al.   Nanomedicine-Nanotechnology Biology and Medicine

NADPH Oxidase-Dependent NLRP3 Inflammasome Activation and its Important Role in Lung Fibrosis by Multiwalled Carbon Nanotubes

(2015) Bingbing Sun et al.   Small

Multi-walled carbon nanotube induced frustrated phagocytosis, cytotoxicity and pro-inflammatory conditions in macrophages are length dependent and greater than that of asbestos

(2015) Matthew S.P. Boyles et al.   TOXICOLOGY IN VITRO

An Allergic Lung Microenvironment Suppresses Carbon Nanotube-Induced Inflammasome Activation via STAT6-Dependent Inhibition of Caspase-1

(2015) Kelly A. Shipkowski et al.   PLoS One

The role of Rho-kinases in IL-1β release through phagocytosis of fibrous particles in human monocytes

(2014) Sanae Kanno et al.   ARCHIVES OF TOXICOLOGY

Apoptotic, inflammatory, and fibrogenic effects of two different types of multi-walled carbon nanotubes in mouse lung

(2014) D. van Berlo et al.   ARCHIVES OF TOXICOLOGY

Role of oxidative stress in carbon nanotube-generated health effects

(2014) Peter Møller et al.   ARCHIVES OF TOXICOLOGY

Multi-walled carbon nanotube length as a critical determinant of bioreactivity with primary human pulmonary alveolar cells

(2014) Sinbad Sweeney et al.   CARBON

The increases in relative mRNA expressions of inflammatory cytokines and chemokines in splenic macrophages from rats exposed to multi-walled carbon nanotubes by whole-body inhalation for 13 weeks

(2014) Takamasa Kido et al.   INHALATION TOXICOLOGY

Complement activation by carbon nanotubes and its influence on the phagocytosis and cytokine response by macrophages

(2014) Kirsten M. Pondman et al.   Nanomedicine-Nanotechnology Biology and Medicine

A secretomics analysis reveals major differences in the macrophage responses towards different types of carbon nanotubes

(2014) Jaana Palomäki et al.   Nanotoxicology

Cytotoxicity of carbon nanotube variants: A comparativein vitroexposure study with A549 epithelial and J774 macrophage cells

(2014) Prem Kumarathasan et al.   Nanotoxicology

Extracellular HMGB1 regulates multi-walled carbon nanotube-induced inflammationin vivo

(2014) Forrest Jessop et al.   Nanotoxicology

Inhalation of rod-like carbon nanotubes causes unconventional allergic airway inflammation

(2014) Elina M Rydman et al.   Particle and Fibre Toxicology

Atomic Layer Deposition Coating of Carbon Nanotubes with Aluminum Oxide Alters Pro-Fibrogenic Cytokine Expression by Human Mononuclear Phagocytes In Vitro and Reduces Lung Fibrosis in Mice In Vivo

(2014) Alexia J. Taylor et al.   PLoS One

Interlaboratory Evaluation of in Vitro Cytotoxicity and Inflammatory Responses to Engineered Nanomaterials: The NIEHS Nano GO Consortium

(2013) Tian Xia et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Biomembrane damage caused by exposure to multi-walled carbon nanotubes

(2013) Kosuke Shimizu et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Distribution and fibrotic response following inhalation exposure to multi-walled carbon nanotubes

(2013) Robert R Mercer et al.   Particle and Fibre Toxicology

Effect of MWCNT size, carboxylation, and purification on in vitro and in vivo toxicity, inflammation and lung pathology

(2013) Raymond F Hamilton et al.   Particle and Fibre Toxicology

Fucosylated Multiwalled Carbon Nanotubes for Kupffer Cells Targeting for the Treatment of Cytokine-Induced Liver Damage

(2013) Richa Gupta et al.   PHARMACEUTICAL RESEARCH

Modulation of Apoptotic Pathways of Macrophages by Surface-Functionalized Multi-Walled Carbon Nanotubes

(2013) Yuanqin Jiang et al.   PLoS One

Carbon Nanotubes: Present and Future Commercial Applications

(2013) M. F. L. De Volder et al.   SCIENCE

Additional Histopathologic Examination of the Lungs from a 3-Month Inhalation Toxicity Study with Multiwall Carbon Nanotubes in Rats

(2013) Silke Treumann et al.   TOXICOLOGICAL SCIENCES

Two-week Toxicity of Multi-walled Carbon Nanotubes by Whole-body Inhalation Exposure in Rats

(2013) Yumi UMEDA et al.   Journal of Toxicologic Pathology

Long-term biopersistence of tangled oxidized carbon nanotubes inside and outside macrophages in rat subcutaneous tissue

(2013) Yoshinori Sato et al.   Scientific Reports

Alarmins, inflammasomes and immunity

(2013) DavidM Ojcius et al.   Biomedical Journal

A Natural Vanishing Act: The Enzyme-Catalyzed Degradation of Carbon Nanomaterials

(2012) Gregg P. Kotchey et al.   ACCOUNTS OF CHEMICAL RESEARCH

Translocation mechanisms of chemically functionalised carbon nanotubes across plasma membranes

(2012) Lara Lacerda et al.   BIOMATERIALS

Multi-walled carbon nanotubes translocate into the pleural cavity and induce visceral mesothelial proliferation in rats

(2012) Jiegou Xu et al.   CANCER SCIENCE

Advances in use of functionalized carbon nanotubes for drug design and discovery

(2012) K K Jain   Expert Opinion on Drug Discovery

NLRP3 inflammasome activation in murine alveolar macrophages and related lung pathology is associated with MWCNT nickel contamination

(2012) Raymond F. Hamilton et al.   INHALATION TOXICOLOGY

In vivocomet assay of multi-walled carbon nanotubes using lung cells of rats intratracheally instilled

(2012) Makoto Ema et al.   JOURNAL OF APPLIED TOXICOLOGY

Comparison of cytotoxic and inflammatory responses of pristine and functionalized multi-walled carbon nanotubes in RAW 264.7 mouse macrophages

(2012) Ting Zhang et al.   JOURNAL OF HAZARDOUS MATERIALS

Effect of MWCNT surface and chemical modification on in vitro cellular response

(2012) Aneta Fraczek-Szczypta et al.   JOURNAL OF NANOPARTICLE RESEARCH

Comparison of Cytotoxicity of Pristine and Covalently Functionalized Multi-Walled Carbon Nanotubes in RAW 264.7 Macrophages

(2012) Man Luo et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Multi-Walled Carbon Nanotubes Induce Apoptosis in RAW 264.7 Cell-Derived Osteoclasts Through Mitochondria-Mediated Death Pathway

(2012) Shefang Ye et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Multi walled carbon nano tubes induced hepatotoxicity in Swiss albino mice

(2012) Kumud Kant Awasthi et al.   MICRON

Multi-walled carbon nanotubes induce COX-2 and iNOS expression via MAP Kinase-dependent and -independent mechanisms in mouse RAW264.7 macrophages

(2012) Jong Lee et al.   Particle and Fibre Toxicology

Critical role of surface chemical modifications induced by length shortening on multi-walled carbon nanotubes-induced toxicity

(2012) Cyrill Bussy et al.   Particle and Fibre Toxicology

Pulmonary surfactant coating of multi-walled carbon nanotubes (MWCNTs) influences their oxidative and pro-inflammatory potential in vitro

(2012) Michael Gasser et al.   Particle and Fibre Toxicology

The mechanism of pleural inflammation by long carbon nanotubes: interaction of long fibres with macrophages stimulates them to amplify pro-inflammatory responses in mesothelial cells

(2012) Fiona A Murphy et al.   Particle and Fibre Toxicology

Multi-walled carbon nanotubes induce apoptosis via mitochondrial pathway and scavenger receptor

(2012) Xiang Wang et al.   TOXICOLOGY IN VITRO

Multiwalled Carbon Nanotubes Interact with Macrophages and Influence Tumor Progression and Metastasis

(2012) Man Yang et al.   Theranostics

Different cellular response mechanisms contribute to the length-dependent cytotoxicity of multi-walled carbon nanotubes

(2012) Dun Liu et al.   Nanoscale Research Letters

Long, Needle-like Carbon Nanotubes and Asbestos Activate the NLRP3 Inflammasome through a Similar Mechanism

(2011) Jaana Palomäki et al.   ACS Nano

Dispersal State of Multiwalled Carbon Nanotubes Elicits Profibrogenic Cellular Responses That Correlate with Fibrogenesis Biomarkers and Fibrosis in the Murine Lung

(2011) Xiang Wang et al.   ACS Nano

Tunable chemistry and morphology of multi-wall carbon nanotubes as a route to non-toxic, theranostic systems

(2011) Sławomir Boncel et al.   BIOMATERIALS

Thickness of Multiwalled Carbon Nanotubes Affects Their Lung Toxicity

(2011) Ivana Fenoglio et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Multiwalled Carbon Nanotubes Induce a Fibrogenic Response by Stimulating Reactive Oxygen Species Production, Activating NF-κB Signaling, and Promoting Fibroblast-to-Myofibroblast Transformation

(2011) Xiaoqing He et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Carbon nanotubes provoke inflammation by inducing the pro-inflammatory genes IL-1β and IL-6

(2011) Chen Qu et al.   GENE

The Role of NADPH Oxidase in Multi-Walled Carbon Nanotubes-Induced Oxidative Stress and Cytotoxicity in Human Macrophages

(2011) Shefang Ye et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Enzymatic Degradation of Multiwalled Carbon Nanotubes

(2011) Yong Zhao et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Effects of single and multi walled carbon nanotubes on macrophages: Cyto and genotoxicity and electron microscopy

(2011) Maria Laura Di Giorgio et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Double-walled carbon nanotubes trigger IL-1β release in human monocytes through Nlrp3 inflammasome activation

(2011) Etienne Meunier et al.   Nanomedicine-Nanotechnology Biology and Medicine

Cellular uptake mechanisms of functionalised multi-walled carbon nanotubes by 3D electron tomography imaging

(2011) Khuloud T. Al-Jamal et al.   Nanoscale

Up-regulation of T lymphocyte and antibody production by inflammatory cytokines released by macrophage exposure to multi-walled carbon nanotubes

(2011) Ana Carolina P Grecco et al.   NANOTECHNOLOGY

Pulmonary toxicity of well-dispersed multi-wall carbon nanotubes following inhalation and intratracheal instillation

(2011) Yasuo Morimoto et al.   Nanotoxicology

Pulmonary fibrotic response to aspiration of multi-walled carbon nanotubes

(2011) Robert R Mercer et al.   Particle and Fibre Toxicology

Coating carbon nanotubes with a polystyrene-based polymer protects against pulmonary toxicity

(2011) Lyes Tabet et al.   Particle and Fibre Toxicology

Diameter and rigidity of multiwalled carbon nanotubes are critical factors in mesothelial injury and carcinogenesis

(2011) H. Nagai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macrophage receptor with collagenous structure (MARCO) is a dynamic adhesive molecule that enhances uptake of carbon nanotubes by CHO-K1 Cells

(2011) Seishiro Hirano et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Assessment of Human Lung Macrophages After Exposure to Multi-Walled Carbon Nanotubes Part I. Cytotoxicity

(2011) Lin Zhu et al.   Nanoscience and Nanotechnology Letters

Functionalization impacts the effects of carbon nanotubes on the immune system of rainbow trout, Oncorhynchus mykiss

(2010) Rebecca Klaper et al.   AQUATIC TOXICOLOGY

Pulmonary Toxicity of Intratracheally Instilled Multiwall Carbon Nanotubes in Male Fischer 344 Rats

(2010) Shigetoshi AISO et al.   INDUSTRIAL HEALTH

Cellular response of RAW 264.7 to spray-coated multi-walled carbon nanotube films with various surfactants

(2010) Hailan Chen et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Nuclear Translocation of Nrf2 and Expression of Antioxidant Defence Genes in THP-1 Cells Exposed to Carbon Nanotubes

(2010) David M. Brown et al.   Journal of Biomedical Nanotechnology

Water Soluble Multi-Walled Carbon Nanotubes Enhance Peritoneal Macrophage Activity In Vivo

(2010) Xiaoyong Deng et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Subcutaneous injection of water-soluble multi-walled carbon nanotubes in tumor-bearing mice boosts the host immune activity

(2010) Jie Meng et al.   NANOTECHNOLOGY

A critical review of the biological mechanisms underlying thein vivoandin vitrotoxicity of carbon nanotubes: The contribution of physico-chemical characteristics

(2010) Helinor J. Johnston et al.   Nanotoxicology

Asbestos, carbon nanotubes and the pleural mesothelium: a review and the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma

(2010) Ken Donaldson et al.   Particle and Fibre Toxicology

Bacterial Lipopolysaccharide Enhances PDGF Signaling and Pulmonary Fibrosis in Rats Exposed to Carbon Nanotubes

(2009) Mark F. Cesta et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Toxicity and imaging of multi-walled carbon nanotubes in human macrophage cells

(2009) Crystal Cheng et al.   BIOMATERIALS

Carbon nanotubes: biomaterial applications

(2009) Naoto Saito et al.   CHEMICAL SOCIETY REVIEWS

Diameter Effects on Cytotoxicity of Multi-Walled Carbon Nanotubes

(2009) X. Wang et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Selective uptake of multi-walled carbon nanotubes by tumor macrophages in a murine glioma model

(2009) Michelle VanHandel et al.   JOURNAL OF NEUROIMMUNOLOGY

Inhalation Toxicity of Multiwall Carbon Nanotubes in Rats Exposed for 3 Months

(2009) Lan Ma-Hock et al.   TOXICOLOGICAL SCIENCES

Proteomics-based safety evaluation of multi-walled carbon nanotubes

(2009) Hisao Haniu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Induction of apoptosis and absence of inflammation in rat lung after intratracheal instillation of multiwalled carbon nanotubes

(2008) D. Elgrabli et al.   TOXICOLOGY

Multi-walled carbon nanotubes injure the plasma membrane of macrophages

(2008) Seishiro Hirano et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY