The role of Rho-kinases in IL-1β release through phagocytosis of fibrous particles in human monocytes

Sulfide induces apoptosis and Rho kinase-dependent cell blebbing in Jurkat cells

(2013) Sanae Kanno et al.   ARCHIVES OF TOXICOLOGY

A novel genotoxicity assay of carbon nanotubes using functional macrophage receptor with collagenous structure (MARCO)-expressing chicken B lymphocytes

(2013) Mohiuddin et al.   ARCHIVES OF TOXICOLOGY

Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome

(2013) Takuma Misawa et al.   NATURE IMMUNOLOGY

Differential activation of the inflammasome in THP-1 cells exposed to chrysotile asbestos and Libby “six-mix” amphiboles and subsequent activation of BEAS-2B cells

(2012) Muyao Li et al.   CYTOKINE

Uric acid as a danger signal in gout and its comorbidities

(2012) Kenneth L. Rock et al.   Nature Reviews Rheumatology

Use of back-scatter electron signals to visualise cell/nanowires interactions in vitro and in vivo; frustrated phagocytosis of long fibres in macrophages and compartmentalisation in mesothelial cells in vivo

(2012) Anja Schinwald et al.   Particle and Fibre Toxicology

Comparison of non-crystalline silica nanoparticles in IL-1β release from macrophages

(2012) Wiggo J Sandberg et al.   Particle and Fibre Toxicology

The Threshold Length for Fiber-Induced Acute Pleural Inflammation: Shedding Light on the Early Events in Asbestos-Induced Mesothelioma

(2012) Anja Schinwald et al.   TOXICOLOGICAL SCIENCES

Long, Needle-like Carbon Nanotubes and Asbestos Activate the NLRP3 Inflammasome through a Similar Mechanism

(2011) Jaana Palomäki et al.   ACS Nano

Serum Amyloid A Activates the NLRP3 Inflammasome via P2X7 Receptor and a Cathepsin B-Sensitive Pathway

(2011) K. Niemi et al.   JOURNAL OF IMMUNOLOGY

Pulmonary Endpoints (Lung Carcinomas and Asbestosis) Following Inhalation Exposure to Asbestos

(2011) Brooke T. Mossman et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Double-walled carbon nanotubes trigger IL-1β release in human monocytes through Nlrp3 inflammasome activation

(2011) Etienne Meunier et al.   Nanomedicine-Nanotechnology Biology and Medicine

A Protective Role for Inflammasome Activation Following Injury

(2011) Akinori Osuka et al.   SHOCK

Macrophage receptor with collagenous structure (MARCO) is a dynamic adhesive molecule that enhances uptake of carbon nanotubes by CHO-K1 Cells

(2011) Seishiro Hirano et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Biopersistent fiber-induced inflammation and carcinogenesis: Lessons learned from asbestos toward safety of fibrous nanomaterials

(2010) Hirotaka Nagai et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Repeated pulmonary exposure to single-walled carbon nanotubes exacerbates allergic inflammation of the airway: Possible role of oxidative stress

(2010) Ken-ichiro Inoue et al.   FREE RADICAL BIOLOGY AND MEDICINE

Single- and Multi-Wall Carbon Nanotubes Versus Asbestos: Are the Carbon Nanotubes a New Health Risk to Humans?

(2010) Maricica Pacurari et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Microtubules Regulate Migratory Polarity through Rho/ROCK Signaling in T Cells

(2010) Aya Takesono et al.   PLoS One

Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation

(2010) Kristiina Rajamäki et al.   PLoS One

Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1  and IL-1 

(2010) A. S. Yazdi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Uptake and cytotoxic effects of multi-walled carbon nanotubes in human bronchial epithelial cells

(2010) Seishiro Hirano et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis

(2008) A. A. Shvedova et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Alterations in Gene Expression in Human Mesothelial Cells Correlate with Mineral Pathogenicity

(2008) Arti Shukla et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Binding of monosodium urate crystals with idiotype protein efficiently promote dendritic cells to induce cytotoxic T cells

(2008) Ippei Sakamaki et al.   CANCER SCIENCE

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE

Multi-walled carbon nanotubes injure the plasma membrane of macrophages

(2008) Seishiro Hirano et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY