Accurate computational design of multipass transmembrane proteins

Global analysis of protein folding using massively parallel design, synthesis, and testing

(2017) Gabriel J. Rocklin et al.   SCIENCE

Unravelling biological macromolecules with cryo-electron microscopy

(2016) Rafael Fernandez-Leiro et al.   NATURE

The coming of age of de novo protein design

(2016) Po-Ssu Huang et al.   NATURE

Steric trapping reveals a cooperativity network in the intramembrane protease GlpG

(2016) Ruiqiong Guo et al.   Nature Chemical Biology

A topological and conformational stability alphabet for multipass membrane proteins

(2016) Xiang Feng et al.   Nature Chemical Biology

A monodisperse transmembrane α-helical peptide barrel

(2016) Kozhinjampara R. Mahendran et al.   Nature Chemistry

Computational design of self-assembling cyclic protein homo-oligomers

(2016) Jorge A. Fallas et al.   Nature Chemistry

A simple DNA handle attachment method for single molecule mechanical manipulation experiments

(2016) Duyoung Min et al.   PROTEIN SCIENCE

De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity

(2016) S. E. Boyken et al.   SCIENCE

Mutational scanning reveals the determinants of protein insertion and association energetics in the plasma membrane

(2016) Assaf Elazar et al.   eLife

Mapping the energy landscape for second-stage folding of a single membrane protein

(2015) Duyoung Min et al.   Nature Chemical Biology

The Membrane- and Soluble-Protein Helix-Helix Interactome: Similar Geometry via Different Interactions

(2015) Shao-Qing Zhang et al.   STRUCTURE

An Integrated Framework Advancing Membrane Protein Modeling and Design

(2015) Rebecca F. Alford et al.   PLoS Computational Biology

A Glimpse of Structural Biology through X-Ray Crystallography

(2014) Yigong Shi   CELL

De novo design of a transmembrane Zn2+-transporting four-helix bundle

(2014) Nathan H. Joh et al.   SCIENCE

High thermodynamic stability of parametrically designed helical bundles

(2014) Po-Ssu Huang et al.   SCIENCE

Improved low-resolution crystallographic refinement with Phenix and Rosetta

(2013) Frank DiMaio et al.   NATURE METHODS

Measuring membrane protein stability under native conditions

(2013) Y.-C. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-Resolution Comparative Modeling with RosettaCM

(2013) Yifan Song et al.   STRUCTURE

Structural differences between thermophilic and mesophilic membrane proteins

(2012) Alejandro D. Meruelo et al.   PROTEIN SCIENCE

RosettaRemodel: A Generalized Framework for Flexible Backbone Protein Design

(2011) Po-Ssu Huang et al.   PLoS One

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural imperatives impose diverse evolutionary constraints on helical membrane proteins

(2009) A. Oberai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modern analytical ultracentrifugation in protein science: A tutorial review

(2002) Jacob Lebowitz et al.   PROTEIN SCIENCE