RosettaRemodel: A Generalized Framework for Flexible Backbone Protein Design

A Chimeric HIV-1 Envelope Glycoprotein Trimer with an Embedded Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF) Domain Induces Enhanced Antibody and T Cell Responses

(2011) Thijs van Montfort et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Computational Design of the Sequence and Structure of a Protein-Binding Peptide

(2011) Deanne W. Sammond et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

De Novo Enzyme Design Using Rosetta3

(2011) Florian Richter et al.   PLoS One

Computational Design of Virus-Like Protein Assemblies on Carbon Nanotube Surfaces

(2011) G. Grigoryan et al.   SCIENCE

Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin

(2011) S. J. Fleishman et al.   SCIENCE

Modulation of Integrin Activation by an Entropic Spring in the β-Knee

(2010) Benoit J. Smagghe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Computational Design of a PAK1 Binding Protein

(2010) Ramesh K. Jha et al.   JOURNAL OF MOLECULAR BIOLOGY

Computational Protein Design Using Flexible Backbone Remodeling and Resurfacing: Case Studies in Structure-Based Antigen Design

(2010) Bruno E. Correia et al.   JOURNAL OF MOLECULAR BIOLOGY

Predicting protein structures with a multiplayer online game

(2010) Seth Cooper et al.   NATURE

Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs

(2010) Justin Ashworth et al.   NUCLEIC ACIDS RESEARCH

Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction

(2010) J. B. Siegel et al.   SCIENCE

A Small Molecule-Regulated Guanine Nucleotide Exchange Factor

(2009) Inna Goreshnik et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Exploitation of binding energy for catalysis and design

(2009) Summer B. Thyme et al.   NATURE

Design of protein-interaction specificity gives selective bZIP-binding peptides

(2009) Gevorg Grigoryan et al.   NATURE

Sub-angstrom accuracy in protein loop reconstruction by robotics-inspired conformational sampling

(2009) Daniel J Mandell et al.   NATURE METHODS

Alteration of enzyme specificity by computational loop remodeling and design

(2009) P. M. Murphy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Motif-directed flexible backbone design of functional interactions

(2009) James J. Havranek et al.   PROTEIN SCIENCE

Macromolecular Modeling with Rosetta

(2008) Rhiju Das et al.   Annual Review of Biochemistry

Computational Design of Calmodulin Mutants with up to 900-Fold Increase in Binding Specificity

(2008) Eliyahu Yosef et al.   JOURNAL OF MOLECULAR BIOLOGY

Kemp elimination catalysts by computational enzyme design

(2008) Daniela Röthlisberger et al.   NATURE

De Novo Computational Design of Retro-Aldol Enzymes

(2008) L. Jiang et al.   SCIENCE