Circulating serum interleukin-6, serum chitinase-3-like protein-1, and plasma vascular endothelial growth factor are not predictive for remission and radiographic progression in patients with early rheumatoid arthritis: post-hoc explorative and validation studies based on the CIMESTRA and OPERA trials

Correlation between circulating VEGF levels and disease activity in rheumatoid arthritis: a meta-analysis

(2016) Young Ho Lee et al.   ZEITSCHRIFT FUR RHEUMATOLOGIE

Clinical and radiographic outcome of a treat-to-target strategy using methotrexate and intra-articular glucocorticoids with or without adalimumab induction: a 2-year investigator-initiated, double-blinded, randomised, controlled trial (OPERA)

(2015) K Hørslev-Petersen et al.   ANNALS OF THE RHEUMATIC DISEASES

Interleukin-6 as a Therapeutic Target

(2015) J.-F. Rossi et al.   CLINICAL CANCER RESEARCH

YKL-40/CHI3L1 drives inflammation on the road of tumor progression

(2015) Stephania Libreros et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Pretreatment multi-biomarker disease activity score and radiographic progression in early RA: results from the SWEFOT trial

(2014) Karen Hambardzumyan et al.   ANNALS OF THE RHEUMATIC DISEASES

A Multibiomarker Disease Activity Score for Rheumatoid Arthritis Predicts Radiographic Joint Damage in the BeSt Study

(2014) I. M. Markusse et al.   JOURNAL OF RHEUMATOLOGY

Adalimumab added to a treat-to-target strategy with methotrexate and intra-articular triamcinolone in early rheumatoid arthritis increased remission rates, function and quality of life. The OPERA Study: an investigator-initiated, randomised, double-blind, parallel-group, placebo-controlled trial

(2013) Kim Hørslev-Petersen et al.   ANNALS OF THE RHEUMATIC DISEASES

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update

(2013) Josef S Smolen et al.   ANNALS OF THE RHEUMATIC DISEASES

Diverse pathological implications of YKL-40: Answers may lie in ‘outside-in’ signaling

(2013) Mansi Prakash et al.   CELLULAR SIGNALLING

Circulating VEGF As a Biological Marker in Patients with Rheumatoid Arthritis? Preanalytical and Biological Variability in Healthy Persons and in Patients

(2013) Merete Lund Hetland et al.   DISEASE MARKERS

Chitinase 3-like 1 Regulates Cellular and Tissue Responses via IL-13 Receptor α2

(2013) Chuan Hua He et al.   Cell Reports

Serum IL-6 and IL-21 are associated with markers of B cell activation and structural progression in early rheumatoid arthritis: results from the ESPOIR cohort

(2012) Jacques-Eric Gottenberg et al.   ANNALS OF THE RHEUMATIC DISEASES

Validation of a novel multibiomarker test to assess rheumatoid arthritis disease activity

(2012) Jeffrey R. Curtis et al.   ARTHRITIS CARE & RESEARCH

Remission and radiographic outcome in rheumatoid arthritis: application of the 2011 ACR/EULAR remission criteria in an observational cohort

(2011) Siri Lillegraven et al.   ANNALS OF THE RHEUMATIC DISEASES

Role of Chitin and Chitinase/Chitinase-Like Proteins in Inflammation, Tissue Remodeling, and Injury

(2011) Chun Geun Lee et al.   Annual Review of Physiology

Plasma YKL-40 levels in healthy subjects from the general population

(2011) Stig E. Bojesen et al.   CLINICA CHIMICA ACTA

IL-6, but not TNF-α, increases plasma YKL-40 in human subjects

(2011) Anders R. Nielsen et al.   CYTOKINE

Radiographic progression and remission rates in early rheumatoid arthritis - MRI bone oedema and anti-CCP predicted radiographic progression in the 5-year extension of the double-blind randomised CIMESTRA trial

(2010) M. L. Hetland et al.   ANNALS OF THE RHEUMATIC DISEASES

Angiopoietin-2 is highly correlated with inflammation and disease activity in recent-onset rheumatoid arthritis and could be predictive for cardiovascular disease

(2010) J. Westra et al.   RHEUMATOLOGY

Proinflammatory Role of Vascular Endothelial Growth Factor in the Pathogenesis of Rheumatoid Arthritis: Prospects for Therapeutic Intervention

(2009) Seung-Ah Yoo et al.   MEDIATORS OF INFLAMMATION

Validation of the 28-joint Disease Activity Score (DAS28) and European League Against Rheumatism response criteria based on C-reactive protein against disease progression in patients with rheumatoid arthritis, and comparison with the DAS28 based on erythrocyte sedimentation rate

(2008) G Wells et al.   ANNALS OF THE RHEUMATIC DISEASES

An explanation for the apparent dissociation between clinical remission and continued structural deterioration in rheumatoid arthritis

(2008) A. K. Brown et al.   ARTHRITIS AND RHEUMATISM

Aggressive combination therapy with intra-articular glucocorticoid injections and conventional disease-modifying anti-rheumatic drugs in early rheumatoid arthritis: second-year clinical and radiographic results from the CIMESTRA study

(2007) M L Hetland et al.   ANNALS OF THE RHEUMATIC DISEASES