Aptamers in HIV research diagnosis and therapy

Unraveling Prion Protein Interactions with Aptamers and Other PrP-Binding Nucleic Acids

(2017) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Building a Molecular Trap for a Serine Protease from Aptamer and Peptide Modules

(2016) Daniel M. Dupont et al.   BIOCONJUGATE CHEMISTRY

The G-quadruplex-forming aptamer AS1411 potently inhibits HIV-1 attachment to the host cell

(2016) Rosalba Perrone et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Identification of an RNA aptamer binding hTERT-derived peptide and inhibiting telomerase activity in MCF7 cells

(2016) Akhil Varshney et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Conformationally selective RNA aptamers allosterically modulate the β2-adrenoceptor

(2016) Alem W Kahsai et al.   Nature Chemical Biology

Aptamers as targeted therapeutics: current potential and challenges

(2016) Jiehua Zhou et al.   NATURE REVIEWS DRUG DISCOVERY

Aptamer Nanomedicine for Cancer Therapeutics: Barriers and Potential for Translation

(2015) Yeh-Hsing Lao et al.   ACS Nano

Modulation of the Coagulation Cascade Using AptamersSignificance

(2015) Rebecca S. Woodruff et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cell-Specific RNA Aptamer against Human CCR5 Specifically Targets HIV-1 Susceptible Cells and Inhibits HIV-1 Infectivity

(2015) Jiehua Zhou et al.   CHEMISTRY & BIOLOGY

Aptamer-Based Sensing of β-Casomorphin-7

(2015) Abhishek Parashar et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A Highlight of Recent Advances in Aptamer Technology and Its Application

(2015) Hongguang Sun et al.   MOLECULES

RNA aptamer inhibitors of a restriction endonuclease

(2015) Estefanía Mondragón et al.   NUCLEIC ACIDS RESEARCH

Aptamers in Diagnostics and Treatment of Viral Infections

(2015) Tomasz Wandtke et al.   Viruses-Basel

Architecture of high-affinity unnatural-base DNA aptamers toward pharmaceutical applications

(2015) Ken-ichiro Matsunaga et al.   Scientific Reports

A Controllable Aptamer-Based Self-Assembled DNA Dendrimer for High Affinity Targeting, Bioimaging and Drug Delivery

(2015) Huimin Zhang et al.   Scientific Reports

High-affinity RNA Aptamers Against the HIV-1 Protease Inhibit Both In Vitro Protease Activity and Late Events of Viral Replication

(2015) Sonald Duclair et al.   Molecular Therapy-Nucleic Acids

Facile Supermolecular Aptamer Inhibitors of L-Selectin

(2015) Elizabeth K. Chang et al.   PLoS One

Blocking interaction of viral gp120 and CD4-expressing T cells by single-stranded DNA aptamers

(2014) Nianxi Zhao et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Insight into HIV-1 reverse transcriptase–aptamer interaction from molecular dynamics simulations

(2014) Niran Aeksiri et al.   JOURNAL OF MOLECULAR MODELING

Towards nanomedicines for neuroAIDS

(2014) Vidya Sagar et al.   REVIEWS IN MEDICAL VIROLOGY

Cell-type-specific, Aptamer-functionalized Agents for Targeted Disease Therapy

(2014) Jiehua Zhou et al.   Molecular Therapy-Nucleic Acids

Aptamer and Its Potential Applications for Food Safety

(2013) Yiyang Dong et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Aptamer-targeted inhibition of mTOR in T cells enhances antitumor immunity

(2013) Alexey Berezhnoy et al.   JOURNAL OF CLINICAL INVESTIGATION

Discovery and Structural Characterization of a New Inhibitor Series of HIV-1 Nucleocapsid Function: NMR Solution Structure Determination of a Ternary Complex Involving a 2:1 Inhibitor/NC Stoichiometry

(2013) Nathalie Goudreau et al.   JOURNAL OF MOLECULAR BIOLOGY

Durable Knockdown and Protection From HIV Transmission in Humanized Mice Treated With Gel-formulated CD4 Aptamer-siRNA Chimeras

(2013) Lee Adam Wheeler et al.   MOLECULAR THERAPY

Past, present and future: 30 years of HIV research

(2013) Françoise Barré-Sinoussi et al.   NATURE REVIEWS MICROBIOLOGY

RAPID-SELEX for RNA Aptamers

(2013) Kylan Szeto et al.   PLoS One

Externally controlled on-demand release of anti-HIV drug using magneto-electric nanoparticles as carriers

(2013) Madhavan Nair et al.   Nature Communications

Nuclease-resistant DNA aptamer on gold nanoparticles for the simultaneous detection of Pb2+ and Hg2+ in human serum

(2012) Chan Ho Chung et al.   BIOSENSORS & BIOELECTRONICS

Therapeutic RNA aptamers in clinical trials

(2012) Padma Sundaram et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

The molecular biology of HIV integrase

(2012) Robert Craigie   Future Virology

Potent Anticoagulant Aptamer Directed against Factor IXa Blocks Macromolecular Substrate Interaction

(2012) Bruce Sullenger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Retroviral Integrase Proteins and HIV-1 DNA Integration

(2012) Lavanya Krishnan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Small Molecule Inhibitors of the HIV-1 Nucleocapsid–Stem-Loop 3 RNA Complex

(2012) Douglas M. Warui et al.   JOURNAL OF MEDICINAL CHEMISTRY

Identification of HIV-1 Inhibitors Targeting the Nucleocapsid Protein

(2012) Sebastian Breuer et al.   JOURNAL OF MEDICINAL CHEMISTRY

UCLA1, a Synthetic Derivative of a gp120 RNA Aptamer, Inhibits Entry of Human Immunodeficiency Virus Type 1 Subtype C

(2012) H. T. Mufhandu et al.   JOURNAL OF VIROLOGY

Transmembrane Protein Aptamers That Inhibit CCR5 Expression and HIV Coreceptor Function

(2012) E. H. Scheideman et al.   JOURNAL OF VIROLOGY

Aptamer-Containing Surfaces for Selective Capture of CD4 Expressing Cells

(2012) Qing Zhou et al.   LANGMUIR

Efficient Reverse Transcription Using Locked Nucleic Acid Nucleotides towards the Evolution of Nuclease Resistant RNA Aptamers

(2012) Lucile Crouzier et al.   PLoS One

High CCR5 Density on Central Memory CD4+ T Cells in Acute HIV-1 Infection Is Mostly Associated with Rapid Disease Progression

(2012) Xue Yang et al.   PLoS One

Nucleic Acid Aptamers Against Proteases

(2011) D. M. Dupont et al.   CURRENT MEDICINAL CHEMISTRY

Tumor-Targeted Drug Delivery with Aptamers

(2011) Y. Zhang et al.   CURRENT MEDICINAL CHEMISTRY

Inhibition of HIV transmission in human cervicovaginal explants and humanized mice using CD4 aptamer-siRNA chimeras

(2011) Lee Adam Wheeler et al.   JOURNAL OF CLINICAL INVESTIGATION

Aptamers for allosteric regulation

(2011) Jan L Vinkenborg et al.   Nature Chemical Biology

Unlocking Biomarker Discovery: Large Scale Application of Aptamer Proteomic Technology for Early Detection of Lung Cancer

(2011) Rachel M. Ostroff et al.   PLoS One

Inhibition of Cell Proliferation by an Anti-EGFR Aptamer

(2011) Na Li et al.   PLoS One

Role of HIV-1 nucleocapsid protein in HIV-1 reverse transcription

(2011) Judith G Levin et al.   RNA Biology

In vitro selected RNA aptamer recognizing glutathione induces ROS mediated apoptosis in the human breast cancer cell line MCF 7

(2011) Jyoti Bala et al.   RNA Biology

CD4+ T Cell Depletion in Human Immunodeficiency Virus (HIV) Infection: Role of Apoptosis

(2011) Michèle Février et al.   Viruses-Basel

Development of Cell-type specific anti-HIV gp120 aptamers for siRNA delivery

(2011) Jiehua Zhou et al.   Jove-Journal of Visualized Experiments

Molecular diagnostic and drug delivery agents based on aptamer-nanomaterial conjugates

(2010) Jung Heon Lee et al.   ADVANCED DRUG DELIVERY REVIEWS

Combination of an Aptamer Probe to CD4 and Antibodies for Multicolored Cell Phenotyping

(2010) Peng Zhang et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Development of aptamer therapeutics

(2010) David HJ Bunka et al.   CURRENT OPINION IN PHARMACOLOGY

Protection of HIV Neutralizing Aptamers against Rectal and Vaginal Nucleases

(2010) Michael D. Moore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RNA Aptamers Directed to Human Immunodeficiency Virus Type 1 Gag Polyprotein Bind to the Matrix and Nucleocapsid Domains and Inhibit Virus Production

(2010) D. Ramalingam et al.   JOURNAL OF VIROLOGY

Genomic SELEX: A discovery tool for genomic aptamers

(2010) Bob Zimmermann et al.   METHODS

Aptamers as therapeutics

(2010) Anthony D. Keefe et al.   NATURE REVIEWS DRUG DISCOVERY

Therapeutic Immunization with HIV-1 Tat Reduces Immune Activation and Loss of Regulatory T-Cells and Improves Immune Function in Subjects on HAART

(2010) Barbara Ensoli et al.   PLoS One

HIV Rev response element (RRE) directs assembly of the Rev homooligomer into discrete asymmetric complexes

(2010) Matthew D. Daugherty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design Strategies for Aptamer-Based Biosensors

(2010) Kun Han et al.   SENSORS

CCR5: From Natural Resistance to a New Anti-HIV Strategy

(2010) Lucia Lopalco   Viruses-Basel

Disease-specific biomarker discovery by aptamers

(2009) Henning Ulrich et al.   CYTOMETRY PART A

RNA aptamers selected against amyloid β-peptide (Aβ) inhibit the aggregation of Aβ

(2009) Tsuyoshi Takahashi et al.   Molecular BioSystems

The integrin  4 7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1

(2009) C. Cicala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Liver Cancer-Specific Aptamers Using Whole Live Cells

(2008) Dihua Shangguan et al.   ANALYTICAL CHEMISTRY

Novel Dual Inhibitory Function Aptamer–siRNA Delivery System for HIV-1 Therapy

(2008) Jiehua Zhou et al.   MOLECULAR THERAPY

Novel bimodular DNA aptamers with guanosine quadruplexes inhibit phylogenetically diverse HIV-1 reverse transcriptases

(2008) D. Michalowski et al.   NUCLEIC ACIDS RESEARCH

Novel Aptamer Inhibitors of Human Immunodeficiency Virus Reverse Transcriptase

(2008) Jeffrey J. DeStefano et al.   OLIGONUCLEOTIDES

Confirmation of a second natural preQ1 aptamer class in Streptococcaceae bacteria

(2008) M. M. Meyer et al.   RNA

Nanotechnology and aptamers: applications in drug delivery

(2008) Etgar Levy-Nissenbaum et al.   TRENDS IN BIOTECHNOLOGY

An aptamer that neutralizes R5 strains of HIV-1 binds to core residues of gp120 in the CCR5 binding site

(2008) Carla Cohen et al.   VIROLOGY

Nucleocapsid protein function in early infection processes

(2008) James A. Thomas et al.   VIRUS RESEARCH

Human macrophages support persistent transcription from unintegrated HIV-1 DNA

(2007) Jeremy Kelly et al.   VIROLOGY