Viruses as key modulators of the TGF-β pathway; a double-edged sword involved in cancer

Evaluation of the expression level of 12/15 lipoxygenase and the related inflammatory factors (CCL5, CCL3) in respiratory syncytial virus infection in mice model

(2017) Vahid Salimi et al.   MICROBIAL PATHOGENESIS

Transforming Growth Factor-β Receptors and Smads: Regulatory Complexity and Functional Versatility

(2017) Erine H. Budi et al.   TRENDS IN CELL BIOLOGY

SARS coronavirus papain-like protease up-regulates the collagen expression through non-Samd TGF-β1 signaling

(2017) Ching-Ying Wang et al.   VIRUS RESEARCH

HBV DNA Integration: Molecular Mechanisms and Clinical Implications

(2017) Thomas Tu et al.   Viruses-Basel

Cutaneous HPV8 and MmuPV1 E6 Proteins Target the NOTCH and TGF-β Tumor Suppressors to Inhibit Differentiation and Sustain Keratinocyte Proliferation

(2017) Jordan M. Meyers et al.   PLoS Pathogens

A BARF1-specific mAb as a new immunotherapeutic tool for the management of EBV-related tumors

(2017) Riccardo Turrini et al.   OncoImmunology

Dichotomous roles of TGF-β in human cancer

(2016) Jennifer J. Huang et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Plasma concentrations of transforming growth factor beta 1 in non-progressive HIV-1 infection correlates with markers of disease progression

(2016) Edward K. Maina et al.   CYTOKINE

TGF-β signalling and liver disease

(2016) Isabel Fabregat et al.   FEBS Journal

TGF-β Signaling in Cancer

(2016) Viqar Syed   JOURNAL OF CELLULAR BIOCHEMISTRY

The Wnt pathway: a key network in cell signalling dysregulated by viruses

(2016) Wendy J. van Zuylen et al.   REVIEWS IN MEDICAL VIROLOGY

Hepatitis B virus X protein in liver tumor microenvironment

(2016) Sha Fu et al.   TUMOR BIOLOGY

Transforming growth factor-β1 in carcinogenesis, progression, and therapy in cervical cancer

(2016) Haiyan Zhu et al.   TUMOR BIOLOGY

Hepatocellular carcinoma and hepatitis B surface protein

(2016) Yong-Wei Li   WORLD JOURNAL OF GASTROENTEROLOGY

Hepatitis B virus X protein amplifies TGF-β promotion on HCC motility through down-regulating PPM1a

(2016) Yuan Liu et al.   Oncotarget

Epstein-Barr virus BARF1-induced NFκB/miR-146a/SMAD4 alterations in stomach cancer cells

(2016) Dong Ha Kim et al.   Oncotarget

SARS coronavirus papain-like protease induces Egr-1-dependent up-regulation of TGF-β1 via ROS/p38 MAPK/STAT3 pathway

(2016) Shih-Wein Li et al.   Scientific Reports

HCV induces transforming growth factor β1 through activation of endoplasmic reticulum stress and the unfolded protein response

(2016) Pattranuch Chusri et al.   Scientific Reports

The Epstein-Barr virus encoded LMP1 oncoprotein modulates cell adhesion via regulation of activin A/TGFβ and β1 integrin signalling

(2016) Mhairi A. Morris et al.   Scientific Reports

Autophagy, TGF-β, and SMAD-2/3 Signaling Regulates Interferon-β Response in Respiratory Syncytial Virus Infected Macrophages

(2016) Swechha M. Pokharel et al.   Frontiers in Cellular and Infection Microbiology

New Mechanism of Hepatic Fibrogenesis: Hepatitis C Virus Infection Induces Transforming Growth Factor β1 Production through Glucose-Regulated Protein 94

(2015) Min Hyeok Jee et al.   JOURNAL OF VIROLOGY

c-Jun N-terminal kinase inhibitor favors transforming growth factor-β to antagonize hepatitis B virus X protein-induced cell growth promotion in hepatocellular carcinoma

(2015) YAN-HUI WU et al.   Molecular Medicine Reports

Targeting the TGFβ pathway for cancer therapy

(2015) Cindy Neuzillet et al.   PHARMACOLOGY & THERAPEUTICS

Epstein-Barr virus latency: current and future perspectives

(2015) Bettina Kempkes et al.   Current Opinion in Virology

Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) Induces the Oncogenic miR-17-92 Cluster and Down-Regulates TGF-β Signaling

(2015) Hong Seok Choi et al.   PLoS Pathogens

TGFβSignaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and Metastasis

(2015) Panagiotis Papageorgis   Journal of Oncology

The Story of Human Cytomegalovirus and Cancer: Increasing Evidence and Open Questions

(2015) Martin Michaelis et al.   NEOPLASIA

LIMK1 Regulates Human Trophoblast Invasion/Differentiation and Is Down-Regulated in Preeclampsia

(2014) Yan Zhou et al.   AMERICAN JOURNAL OF PATHOLOGY

Viruses and Human Cancers: a Long Road of Discovery of Molecular Paradigms

(2014) M. K. White et al.   CLINICAL MICROBIOLOGY REVIEWS

TGF-beta Signaling in Cancer Treatment

(2014) Isabel Fabregat et al.   CURRENT PHARMACEUTICAL DESIGN

Influenza Promotes Collagen Deposition via αvβ6 Integrin-mediated Transforming Growth Factor β Activation

(2014) Lisa Jolly et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ebola Virus Modulates Transforming Growth Factor   Signaling and Cellular Markers of Mesenchyme-Like Transition in Hepatocytes

(2014) J. Kindrachuk et al.   JOURNAL OF VIROLOGY

Hepatitis B Virus Regulates Apoptosis and Tumorigenesis through the MicroRNA-15a-Smad7-Transforming Growth Factor Beta Pathway

(2014) Ningning Liu et al.   JOURNAL OF VIROLOGY

Hepatitis C virus NS5A drives a PTEN-PI3K/Akt feedback loop to support cell survival

(2014) Du Cheng et al.   LIVER INTERNATIONAL

Influenza viral neuraminidase primes bacterial coinfection through TGF-β–mediated expression of host cell receptors

(2014) Ning Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic analysis of human oncogenic viruses in colon cancer revealed EBV latency in lymphoid infiltrates

(2014) Loretta Fiorina et al.   Infectious Agents and Cancer

The hepatitis B virus-associated tumor microenvironment in hepatocellular carcinoma

(2014) Pengyuan Yang et al.   National Science Review

Predicting risk of cancer during HIV infection

(2013) Álvaro H. Borges et al.   AIDS

Hepatitis C virus/human interactome identifies SMURF2 and the viral protease as critical elements for the control of TGF-β signaling

(2013) Amandine Verga-Gérard et al.   FASEB JOURNAL

Regulation of TGF-  family signalling by ubiquitination and deubiquitination

(2013) T. Imamura et al.   JOURNAL OF BIOCHEMISTRY

HCV core-mediated activation of latent TGF-β via thrombospondin drives the crosstalk between hepatocytes and stromal environment

(2013) Nassima Benzoubir et al.   JOURNAL OF HEPATOLOGY

Hepatitis B Virus Inhibits Apoptosis of Hepatoma Cells by Sponging the MicroRNA 15a/16 Cluster

(2013) N. Liu et al.   JOURNAL OF VIROLOGY

Expression of HPV16 E5 down-modulates the TGFbeta signaling pathway

(2013) Deborah French et al.   Molecular Cancer

A Kaposi's Sarcoma-Associated Herpesvirus MicroRNA and Its Variants Target the Transforming Growth Factor   Pathway To Promote Cell Survival

(2012) X. Lei et al.   JOURNAL OF VIROLOGY

TGFβ signalling in context

(2012) Joan Massagué   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Effects of Activin and TGFβ on p21 in Colon Cancer

(2012) Jessica Bauer et al.   PLoS One

Correlation between TGF-β1 expression and proteomic profiling induced by severe acute respiratory syndrome coronavirus papain-like protease

(2012) Shih-Wen Li et al.   PROTEOMICS

HTLV-1 bZIP factor enhances TGF-  signaling through p300 coactivator

(2011) T. Zhao et al.   BLOOD

Non-Smad signaling pathways

(2011) Yabing Mu et al.   CELL AND TISSUE RESEARCH

Kaposi's Sarcoma-Associated Herpesvirus-Encoded MicroRNA miR-K12-11 Attenuates Transforming Growth Factor Beta Signaling through Suppression of SMAD5

(2011) Y. Liu et al.   JOURNAL OF VIROLOGY

Hepatitis C Virus Regulates Transforming Growth Factor β1 Production Through the Generation of Reactive Oxygen Species in a Nuclear Factor κB–Dependent Manner

(2010) Wenyu Lin et al.   GASTROENTEROLOGY

Upregulation of Id1 by Epstein-Barr Virus-encoded LMP1 confers resistance to TGFβ-mediated growth inhibition

(2010) Angela KF Lo et al.   Molecular Cancer

Human Cytomegalovirus Induces TGF-β1 Activation in Renal Tubular Epithelial Cells after Epithelial-to-Mesenchymal Transition

(2010) Masako Shimamura et al.   PLoS Pathogens

Transforming Growth Factor-β: Activation by Neuraminidase and Role in Highly Pathogenic H5N1 Influenza Pathogenesis

(2010) Christina M. Carlson et al.   PLoS Pathogens

Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)-β signaling from tumor suppression to oncogenesis in early chronic hepatitis B

(2009) Miki Murata et al.   HEPATOLOGY

Expression and mutational analysis of TGF-β/Smads signaling in human cervical cancers

(2009) Kyung-Do Ki et al.   Journal of Gynecologic Oncology

Reovirus Activates Transforming Growth Factor   and Bone Morphogenetic Protein Signaling Pathways in the Central Nervous System That Contribute to Neuronal Survival following Infection

(2009) J. D. Beckham et al.   JOURNAL OF VIROLOGY

Liver Cancer-Derived Hepatitis C Virus Core Proteins Shift TGF-Beta Responses from Tumor Suppression to Epithelial-Mesenchymal Transition

(2009) Serena Battaglia et al.   PLoS One

Adenovirus E1A and E1B-19K proteins protect human hepatoma cells from transforming growth factor β1-induced apoptosis

(2009) Vera L. Tarakanova et al.   VIRUS RESEARCH

Induction of an Epithelial Integrin αvβ6 in Human Cytomegalovirus-Infected Endothelial Cells Leads to Activation of Transforming Growth Factor-β1 and Increased Collagen Production

(2008) Takako Tabata et al.   AMERICAN JOURNAL OF PATHOLOGY

KSHV LANA inhibits TGF-  signaling through epigenetic silencing of the TGF-  type II receptor

(2008) D. L. Di Bartolo et al.   BLOOD

HIV Increases HCV Replication in a TGF-β1–Dependent Manner

(2008) Wenyu Lin et al.   GASTROENTEROLOGY

The human papillomavirus E7 oncoprotein

(2008) Margaret E. McLaughlin-Drubin et al.   VIROLOGY