Penetration into membrane of amino-terminal region of SecA when associated with SecYEG in active complexes

The SecA protein deeply penetrates into the SecYEG channel during insertion, contacting most channel transmembrane helices and periplasmic regions

(2017) Tithi Banerjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Single-Molecule Peptide–Lipid Affinity Assay Reveals Interplay between Solution Structure and Partitioning

(2017) Tina R. Matin et al.   LANGMUIR

Lipids Activate SecA for High Affinity Binding to the SecYEG Complex

(2016) Sabrina Koch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for the antifolding activity of a molecular chaperone

(2016) Chengdong Huang et al.   NATURE

The Basis of Asymmetry in the SecA:SecB Complex

(2015) Yuying Suo et al.   JOURNAL OF MOLECULAR BIOLOGY

A “Push and Slide” Mechanism Allows Sequence-Insensitive Translocation of Secretory Proteins by the SecA ATPase

(2014) Benedikt W. Bauer et al.   CELL

Stoichiometry of SecYEG in the active translocase of Escherichia coli varies with precursor species

(2013) C. Mao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational changes of the chaperone SecB upon binding to a model substrate – bovine pancreatic trypsin inhibitor (BPTI)

(2011) Michaela M. Haimann et al.   BIOLOGICAL CHEMISTRY

SecA Alone Can Promote Protein Translocation and Ion Channel Activity

(2011) Ying-hsin Hsieh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Orientation of SecA and SecB in Complex, Derived from Disulfide Cross-Linking

(2010) Y. Suo et al.   JOURNAL OF BACTERIOLOGY

Direct identification of the site of binding on the chaperone SecB for the amino terminus of the translocon motor SecA

(2010) Linda L. Randall et al.   PROTEIN SCIENCE

Signal peptides are allosteric activators of the protein translocase

(2009) Giorgos Gouridis et al.   NATURE

Export chaperone SecB uses one surface of interaction for diverse unfolded polypeptide ligands

(2009) Angela A. Lilly et al.   PROTEIN SCIENCE

Structure of a complex of the ATPase SecA and the protein-translocation channel

(2008) Jochen Zimmer et al.   NATURE

Protein Translocation Across the Bacterial Cytoplasmic Membrane

(2007) Arnold J.M. Driessen et al.   Annual Review of Biochemistry

Protein secondary structure analyses from circular dichroism spectroscopy: Methods and reference databases

(2007) Lee Whitmore et al.   BIOPOLYMERS