Conformational control and DNA-binding mechanism of the metazoan origin recognition complex

Structure of a human cap-dependent 48S translation pre-initiation complex

(2018) Boris Eliseev et al.   NUCLEIC ACIDS RESEARCH

From structure to mechanism—understanding initiation of DNA replication

(2017) Alberto Riera et al.   GENES & DEVELOPMENT

Structural basis of Mcm2–7 replicative helicase loading by ORC–Cdc6 and Cdt1

(2017) Zuanning Yuan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mechanisms for initiating cellular DNA replication

(2017) Franziska Bleichert et al.   SCIENCE

Structural basis of Mcm2–7 replicative helicase loading by ORC–Cdc6 and Cdt1

(2017) Zuanning Yuan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the active form of human origin recognition complex and its ATPase motor module

(2017) Ante Tocilj et al.   eLife

Crystal structure of the eukaryotic origin recognition complex

(2015) Franziska Bleichert et al.   NATURE

Specific binding of eukaryotic ORC to DNA replication origins depends on highly conserved basic residues

(2015) Hironori Kawakami et al.   Scientific Reports

ATPase-dependent quality control of DNA replication origin licensing

(2013) Jordi Frigola et al.   NATURE

Lysine-specific chemical cross-linking of protein complexes and identification of cross-linking sites using LC-MS/MS and the xQuest/xProphet software pipeline

(2013) Alexander Leitner et al.   Nature Protocols

Cryo-EM structure of a helicase loading intermediate containing ORC–Cdc6–Cdt1–MCM2-7 bound to DNA

(2013) Jingchuan Sun et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Meier-Gorlin syndrome mutation in a conserved C-terminal helix of Orc6 impedes origin recognition complex formation

(2013) Franziska Bleichert et al.   eLife

False discovery rate estimation for cross-linked peptides identified by mass spectrometry

(2012) Thomas Walzthoeni et al.   NATURE METHODS

Cdc6-Induced Conformational Changes in ORC Bound to Origin DNA Revealed by Cryo-Electron Microscopy

(2012) Jingchuan Sun et al.   STRUCTURE

Structural analysis of human Orc6 protein reveals a homology with transcription factor TFIIB

(2011) S. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Concerted Loading of Mcm2–7 Double Hexamers around DNA during DNA Replication Origin Licensing

(2009) Dirk Remus et al.   CELL

The origin recognition complex protein family

(2009) Bernard P Duncker et al.   GENOME BIOLOGY

Multiple Mechanisms Contribute toSchizosaccharomyces pombeOrigin Recognition Complex-DNA Interactions

(2008) Christopher R. Houchens et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Single particle EM studies of the Drosophila melanogaster origin recognition complex and evidence for DNA wrapping

(2008) Megan G. Clarey et al.   JOURNAL OF STRUCTURAL BIOLOGY