Intracellular Ca2+stores control in vivo neuronal hyperactivity in a mouse model of Alzheimer’s disease

Heightened cortical excitability in aged rodents with memory impairment

(2017) Rebecca P. Haberman et al.   NEUROBIOLOGY OF AGING

Axonal Endoplasmic Reticulum Ca 2+ Content Controls Release Probability in CNS Nerve Terminals

(2017) Jaime de Juan-Sanz et al.   NEURON

Targeting Neural Hyperactivity as a Treatment to Stem Progression of Late-Onset Alzheimer’s Disease

(2017) Rebecca P. Haberman et al.   Neurotherapeutics

BACE inhibition-dependent repair of Alzheimer’s pathophysiology

(2017) Aylin D. Keskin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Incidence and impact of subclinical epileptiform activity in Alzheimer's disease

(2016) Keith A. Vossel et al.   ANNALS OF NEUROLOGY

Network abnormalities and interneuron dysfunction in Alzheimer disease

(2016) Jorge J. Palop et al.   NATURE REVIEWS NEUROSCIENCE

Nitric Oxide Signaling Is Recruited As a Compensatory Mechanism for Sustaining Synaptic Plasticity in Alzheimer's Disease Mice

(2015) S. Chakroborty et al.   JOURNAL OF NEUROSCIENCE

Aging-Related Hyperexcitability in CA3 Pyramidal Neurons Is Mediated by Enhanced A-Type K+ Channel Function and Expression

(2015) D. Simkin et al.   JOURNAL OF NEUROSCIENCE

Network-wide dysregulation of calcium homeostasis in Alzheimer’s disease

(2014) Bianca Brawek et al.   CELL AND TISSUE RESEARCH

Neuronal activity regulates extracellular tau in vivo

(2014) Kaoru Yamada et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Longitudinal PET-MRI reveals β-amyloid deposition and rCBF dynamics and connects vascular amyloidosis to quantitative loss of perfusion

(2014) Florian C Maier et al.   NATURE MEDICINE

The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease

(2014) Tara L. Spires-Jones et al.   NEURON

Dendritic Structural Degeneration Is Functionally Linked to Cellular Hyperexcitability in a Mouse Model of Alzheimer’s Disease

(2014) Zuzana Šišková et al.   NEURON

Reduced Synaptic STIM2 Expression and Impaired Store-Operated Calcium Entry Cause Destabilization of Mature Spines in Mutant Presenilin Mice

(2014) Suya Sun et al.   NEURON

Calcium channelopathies and Alzheimer's disease: Insight into therapeutic success and failures

(2013) Shreaya Chakroborty et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Organization of Cortical and Thalamic Input to Pyramidal Neurons in Mouse Motor Cortex

(2013) B. M. Hooks et al.   JOURNAL OF NEUROSCIENCE

Dendritic spikes enhance stimulus selectivity in cortical neurons in vivo

(2013) Spencer L. Smith et al.   NATURE

Role of endoplasmic reticulum Ca2+ signaling in the pathogenesis of Alzheimer disease

(2013) Elena Popugaeva et al.   Frontiers in Molecular Neuroscience

Inhibitory Interneuron Deficit Links Altered Network Activity and Cognitive Dysfunction in Alzheimer Model

(2012) Laure Verret et al.   CELL

Imaging microcircuit function in healthy and diseased brain

(2012) Olga Garaschuk   EXPERIMENTAL NEUROLOGY

Early Presynaptic and Postsynaptic Calcium Signaling Abnormalities Mask Underlying Synaptic Depression in Presymptomatic Alzheimer's Disease Mice

(2012) S. Chakroborty et al.   JOURNAL OF NEUROSCIENCE

Reduction of Hippocampal Hyperactivity Improves Cognition in Amnestic Mild Cognitive Impairment

(2012) Arnold Bakker et al.   NEURON

Stabilizing ER Ca2+ Channel Function as an Early Preventative Strategy for Alzheimer’s Disease

(2012) Shreaya Chakroborty et al.   PLoS One

Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model

(2012) P. E. Sanchez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Critical role of soluble amyloid-  for early hippocampal hyperactivity in a mouse model of Alzheimer's disease

(2012) M. A. Busche et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Staged decline of neuronal function in vivo in an animal model of Alzheimer's disease

(2012) Christine Grienberger et al.   Nature Communications

Role of presenilin1 in structural plasticity of cortical dendritic spines in vivo

(2011) Christian K. E. Jung et al.   JOURNAL OF NEUROCHEMISTRY

Microglial calcium signal acts as a rapid sensor of single neuron damage in vivo

(2010) Gerhard Eichhoff et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Role of Presenilins in Neuronal Calcium Homeostasis

(2010) H. Zhang et al.   JOURNAL OF NEUROSCIENCE

NMDA-Mediated Ca2+ Influx Drives Aberrant Ryanodine Receptor Activation in Dendrites of Young Alzheimer's Disease Mice

(2010) I. Goussakov et al.   JOURNAL OF NEUROSCIENCE

Dendritic organization of sensory input to cortical neurons in vivo

(2010) Hongbo Jia et al.   NATURE

Epilepsy and Cognitive Impairments in Alzheimer Disease

(2009) Jorge J. Palop   ARCHIVES OF NEUROLOGY

The cortical innate immune response increases local neuronal excitability leading to seizures

(2009) K. M. Rodgers et al.   BRAIN

Intracellular calcium signalling in Alzheimer’s disease

(2009) Marina Hermes et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Deviant Ryanodine Receptor-Mediated Calcium Release Resets Synaptic Homeostasis in Presymptomatic 3xTg-AD Mice

(2009) S. Chakroborty et al.   JOURNAL OF NEUROSCIENCE

Amyloid  -Induced Neuronal Hyperexcitability Triggers Progressive Epilepsy

(2009) R. Minkeviciene et al.   JOURNAL OF NEUROSCIENCE

Presenilins are essential for regulating neurotransmitter release

(2009) Chen Zhang et al.   NATURE

Endocytosis Is Required for Synaptic Activity-Dependent Release of Amyloid-β In Vivo

(2008) John R. Cirrito et al.   NEURON

Multiple Roles of Calcium Ions in the Regulation of Neurotransmitter Release

(2008) Erwin Neher et al.   NEURON

Use-dependent amplification of presynaptic Ca2+ signaling by axonal ryanodine receptors at the hippocampal mossy fiber synapse

(2008) H. Shimizu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease

(2008) M. A. Busche et al.   SCIENCE

Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease

(2008) Ilya Bezprozvanny et al.   TRENDS IN NEUROSCIENCES

Layer, column and cell-type specific genetic manipulation in mouse barrel cortex

(2008) Rachel Aronoff   Frontiers in Neuroscience