Atomic mutagenesis of stop codon nucleotides reveals the chemical prerequisites for release factor-mediated peptide release

Critical 23S rRNA interactions for macrolide-dependent ribosome stalling on the ErmCL nascent peptide chain

(2017) Miriam Koch et al.   NUCLEIC ACIDS RESEARCH

Translation of poly(A) tails leads to precise mRNA cleavage

(2017) Nicholas R. Guydosh et al.   RNA

Origin of the omnipotence of eukaryotic release factor 1

(2017) Christoffer Lind et al.   Nature Communications

Mechanism of Translation Termination: RF1 Dissociation Follows Dissociation of RF3 from the Ribosome

(2016) Xinying Shi et al.   BIOCHEMISTRY

Reassigning stop codons via translation termination: How a few eukaryotes broke the dogma

(2016) Elena Alkalaeva et al.   BIOESSAYS

Genetic Codes with No Dedicated Stop Codon: Context-Dependent Translation Termination

(2016) Estienne Carl Swart et al.   CELL

Structural Basis for Translation Termination on a Pseudouridylated Stop Codon

(2016) Egor Svidritskiy et al.   JOURNAL OF MOLECULAR BIOLOGY

Novel Ciliate Genetic Code Variants Including the Reassignment of All Three Stop Codons to Sense Codons inCondylostoma magnum

(2016) Stephen M. Heaphy et al.   MOLECULAR BIOLOGY AND EVOLUTION

Structural basis for stop codon recognition in eukaryotes

(2015) Alan Brown et al.   NATURE

New insights into stop codon recognition by eRF1

(2015) Sandra Blanchet et al.   NUCLEIC ACIDS RESEARCH

Structure of a human translation termination complex

(2015) Sarah Matheisl et al.   NUCLEIC ACIDS RESEARCH

Nucleotide modifications within bacterial messenger RNAs regulate their translation and are able to rewire the genetic code

(2015) Thomas Philipp Hoernes et al.   NUCLEIC ACIDS RESEARCH

The integrity of the G2421-C2395 base pair in the ribosomal E-site is crucial for protein synthesis

(2015) Miriam Koch et al.   RNA Biology

Thermodynamic and Kinetic Insights into Stop Codon Recognition by Release Factor 1

(2014) Krista Trappl et al.   PLoS One

RF3:GTP promotes rapid dissociation of the class 1 termination factor

(2014) K. S. Koutmou et al.   RNA

Residue mutations and their impact on protein structure and function: detecting beneficial and pathogenic changes

(2013) Romain A. Studer et al.   BIOCHEMICAL JOURNAL

Eukaryotic Release Factor 3 Is Required for Multiple Turnovers of Peptide Release Catalysis by Eukaryotic Release Factor 1

(2013) Daniel E. Eyler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of the 70S Ribosome Bound with the Q253P Mutant Form of Release Factor RF2

(2013) Natalia Santos et al.   STRUCTURE

A Role for the 2′ OH of Peptidyl-tRNA Substrate in Peptide Release on the Ribosome Revealed through RF-Mediated Rescue

(2012) Jeffrey J. Shaw et al.   CHEMISTRY & BIOLOGY

Structural view on recycling of archaeal and eukaryotic ribosomes after canonical termination and ribosome rescue

(2012) Sibylle Franckenberg et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

A new understanding of the decoding principle on the ribosome

(2012) Natalia Demeshkina et al.   NATURE

Identification of eRF1 residues that play critical and complementary roles in stop codon recognition

(2012) S. E. Conard et al.   RNA

The Elongation, Termination, and Recycling Phases of Translation in Eukaryotes

(2012) T. E. Dever et al.   Cold Spring Harbor Perspectives in Biology

Kinetic analysis reveals the ordered coupling of translation termination and ribosome recycling in yeast

(2011) C. J. Shoemaker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ribosome recycling depends on a mechanistic link between the FeS cluster domain and a conformational switch of the twin-ATPase ABCE1

(2011) D. Barthelme et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural aspects of translation termination on the ribosome

(2011) A. A. Korostelev   RNA

Molecular recognition and catalysis in translation termination complexes

(2011) Bruno P. Klaholz   TRENDS IN BIOCHEMICAL SCIENCES

tRNA mimicry in translation termination and beyond

(2011) Yoshikazu Nakamura et al.   Wiley Interdisciplinary Reviews-RNA

Histidine 197 in Release Factor 1 Is Essential for A Site Binding and Peptide Release

(2010) Andrew Field et al.   BIOCHEMISTRY

Recognition of the amber UAG stop codon by release factor RF1

(2010) Andrei Korostelev et al.   EMBO JOURNAL

The Role of ABCE1 in Eukaryotic Posttermination Ribosomal Recycling

(2010) Andrey V. Pisarev et al.   MOLECULAR CELL

Principles of stop-codon reading on the ribosome

(2010) Johan Sund et al.   NATURE

Atomic mutagenesis reveals A2660 of 23S ribosomal RNA as key to EF-G GTPase activation

(2010) Nina Clementi et al.   Nature Chemical Biology

Structure of the 70S ribosome bound to release factor 2 and a substrate analog provides insights into catalysis of peptide release

(2010) H. Jin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The codon specificity of eubacterial release factors is determined by the sequence and size of the recognition loop

(2010) D. J. Young et al.   RNA

Three distinct peptides from the N domain of translation termination factor eRF1 surround stop codon in the ribosome

(2010) K. N. Bulygin et al.   RNA

Kinetics of Stop Codon Recognition by Release Factor 1

(2009) Byron Hetrick et al.   BIOCHEMISTRY

Peptide Release on the Ribosome: Mechanism and Implications for Translational Control

(2008) Elaine M. Youngman et al.   Annual Review of Microbiology

Molecular Mechanism of Drug-Dependent Ribosome Stalling

(2008) Nora Vazquez-Laslop et al.   MOLECULAR CELL

Structural basis for translation termination on the 70S ribosome

(2008) Martin Laurberg et al.   NATURE

Crystal structure of a translation termination complex formed with release factor RF2

(2008) A. Korostelev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insights into Translational Termination from the Structure of RF2 Bound to the Ribosome

(2008) A. Weixlbaumer et al.   SCIENCE