Nucleotide modifications within bacterial messenger RNAs regulate their translation and are able to rewire the genetic code

What do we know about ribosomal RNA methylation in Escherichia coli?

(2015) O.V. Sergeeva et al.   BIOCHIMIE

N6-methyladenosine Modulates Messenger RNA Translation Efficiency

(2015) Xiao Wang et al.   CELL

Chemical pulldown reveals dynamic pseudouridylation of the mammalian transcriptome

(2015) Xiaoyu Li et al.   Nature Chemical Biology

Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly

(2015) Yury S Polikanov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Widespread occurrence ofN6-methyladenosine in bacterial mRNA

(2015) Xin Deng et al.   NUCLEIC ACIDS RESEARCH

O6-Methylguanosine leads to position-dependent effects on ribosome speed and fidelity

(2015) Benjamin H. Hudson et al.   RNA

Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan

(2015) Markus Schosserer et al.   Nature Communications

Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly

(2015) Yury S Polikanov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Modify or die? - RNA modification defects in metazoans

(2015) L Peter Sarin et al.   RNA Biology

High-Resolution Structure of the Eukaryotic 80S Ribosome

(2014) Gulnara Yusupova et al.   Annual Review of Biochemistry

Emerging Roles of RNA Modification: m 6 A and U-Tail

(2014) Mihye Lee et al.   CELL

Transcriptome-wide Mapping Reveals Widespread Dynamic-Regulated Pseudouridylation of ncRNA and mRNA

(2014) Schraga Schwartz et al.   CELL

Pseudouridine in a new era of RNA modifications

(2014) Boxuan Simen Zhao et al.   CELL RESEARCH

Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells

(2014) Thomas M. Carlile et al.   NATURE

N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells

(2014) Yang Wang et al.   NATURE CELL BIOLOGY

Gene expression regulation mediated through reversible m6A RNA methylation

(2014) Ye Fu et al.   NATURE REVIEWS GENETICS

The dynamic epitranscriptome: N6-methyladenosine and gene expression control

(2014) Kate D. Meyer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Transcriptome-Wide Mapping of Pseudouridines: Pseudouridine Synthases Modify Specific mRNAs in S. cerevisiae

(2014) Alexander F. Lovejoy et al.   PLoS One

Role of tRNA modifications in human diseases

(2014) Adrian Gabriel Torres et al.   TRENDS IN MOLECULAR MEDICINE

An Active Role for the Ribosome in Determining the Fate of Oxidized mRNA

(2014) Carrie L. Simms et al.   Cell Reports

Functional implications of ribosomal RNA methylation in response to environmental stress

(2013) Kevin C. Baldridge et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Steric Complementarity in the Decoding Center Is Important for tRNA Selection by the Ribosome

(2013) Prashant K. Khade et al.   JOURNAL OF MOLECULAR BIOLOGY

Unusual base pairing during the decoding of a stop codon by the ribosome

(2013) Israel S. Fernández et al.   NATURE

N6-methyl-adenosine modification in messenger and long non-coding RNA

(2013) Tao Pan   TRENDS IN BIOCHEMICAL SCIENCES

Transcriptome-Wide Mapping of 5-methylcytidine RNA Modifications in Bacteria, Archaea, and Yeast Reveals m5C within Archaeal mRNAs

(2013) Sarit Edelheit et al.   PLoS Genetics

Mapping and significance of the mRNA methylome

(2013) Tennille Sibbritt et al.   Wiley Interdisciplinary Reviews-RNA

Biosynthesis and Function of Posttranscriptional Modifications of Transfer RNAs

(2012) Basma El Yacoubi et al.   Annual Review of Genetics

Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

(2012) Kate D. Meyer et al.   CELL

Increased Erythropoiesis in Mice Injected With Submicrogram Quantities of Pseudouridine-containing mRNA Encoding Erythropoietin

(2012) Katalin Karikó et al.   MOLECULAR THERAPY

A new understanding of the decoding principle on the ribosome

(2012) Natalia Demeshkina et al.   NATURE

Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA

(2012) Jeffrey E. Squires et al.   NUCLEIC ACIDS RESEARCH

MODOMICS: a database of RNA modification pathways—2013 update

(2012) Magdalena A. Machnicka et al.   NUCLEIC ACIDS RESEARCH

Rationalization and prediction of selective decoding of pseudouridine-modified nonsense and sense codons

(2012) M. Parisien et al.   RNA

Converting nonsense codons into sense codons by targeted pseudouridylation

(2011) John Karijolich et al.   NATURE

Expression of therapeutic proteins after delivery of chemically modified mRNA in mice

(2011) Michael S D Kormann et al.   NATURE BIOTECHNOLOGY

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

Generation of chemically engineered ribosomes for atomic mutagenesis studies on protein biosynthesis

(2011) Matthias D Erlacher et al.   Nature Protocols

Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA

(2011) Katalin Karikó et al.   NUCLEIC ACIDS RESEARCH

A comparative study of protein synthesis in in vitro systems: from the prokaryotic reconstituted to the eukaryotic extract-based

(2008) Jason R Hillebrecht et al.   BMC BIOTECHNOLOGY

Molecular Mechanism of Drug-Dependent Ribosome Stalling

(2008) Nora Vazquez-Laslop et al.   MOLECULAR CELL

Incorporation of Pseudouridine Into mRNA Yields Superior Nonimmunogenic Vector With Increased Translational Capacity and Biological Stability

(2008) Katalin Karikó et al.   MOLECULAR THERAPY

The preparation of site-specifically modified riboswitch domains as an example for enzymatic ligation of chemically synthesized RNA fragments

(2008) Kathrin Lang et al.   Nature Protocols