CHIP E3 ligase mediates proteasomal degradation of the proliferation regulatory protein ALDH1L1 during the transition of NIH3T3 fibroblasts from G0/G1 to S-phase

Systematic approaches to identify E3 ligase substrates

(2016) M. Iconomou et al.   BIOCHEMICAL JOURNAL

A Decade of Boon or Burden: What Has the CHIP Ever Done for Cellular Protein Quality Control Mechanism Implicated in Neurodegeneration and Aging?

(2016) Vibhuti Joshi et al.   Frontiers in Molecular Neuroscience

Ubiquitin-like protein MNSFβ covalently binds to cytosolic 10-formyltetrahydrofolate dehydrogenase and regulates thymocyte function

(2015) Morihiko Nakamura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MiR-1178 Promotes the Proliferation, G1/S Transition, Migration and Invasion of Pancreatic Cancer Cells by Targeting CHIP

(2015) Zhe Cao et al.   PLoS One

Increased expression of glycinamide ribonucleotide transformylase is associated with a poor prognosis in hepatocellular carcinoma, and it promotes liver cancer cell proliferation

(2014) Xia Cong et al.   HUMAN PATHOLOGY

Modulation of the Hsp90 Chaperone Cycle by a Stringent Client Protein

(2014) Oliver Robin Lorenz et al.   MOLECULAR CELL

JNK1/2 regulate Bid by direct phosphorylation at Thr59 in response to ALDH1L1

(2014) A Prakasam et al.   Cell Death & Disease

Epigenetic Alterations of Chromosome 3 Revealed by NotI-Microarrays in Clear Cell Renal Cell Carcinoma

(2014) Alexey A. Dmitriev et al.   Biomed Research International

The E3 Ligase CHIP: Insights into Its Structure and Regulation

(2014) Indranil Paul et al.   Biomed Research International

Ubiquitin Ligases and Cell Cycle Control

(2013) Leonardo K. Teixeira et al.   Annual Review of Biochemistry

Ubiquitin-independent proteasomal degradation

(2013) Jenny Erales et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Novel tumor suppressor candidates on chromosome 3 revealed by NotI-microarrays in cervical cancer

(2013) Vera N. Senchenko et al.   Epigenetics

A Novel Tumor Suppressor Function of Glycine N-Methyltransferase Is Independent of Its Catalytic Activity but Requires Nuclear Localization

(2013) Suchandra DebRoy et al.   PLoS One

Characterization of the bipartite degron that regulates ubiquitin-independent degradation of thymidylate synthase

(2012) Karen W. Barbour et al.   BIOSCIENCE REPORTS

Genetic and epigenetic analysis of non-small cell lung cancer with NotI-microarrays

(2012) Alexey A. Dmitriev et al.   Epigenetics

Emerging regulatory mechanisms in ubiquitin-dependent cell cycle control

(2012) A. Mocciaro et al.   JOURNAL OF CELL SCIENCE

Competition between Sumoylation and Ubiquitination of Serine Hydroxymethyltransferase 1 Determines Its Nuclear Localization and Its Accumulation in the Nucleus

(2011) Donald D. Anderson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decreased expression of ALDH1L1 is associated with a poor prognosis in hepatocellular carcinoma

(2011) Xiao-Qian Chen et al.   MEDICAL ONCOLOGY

Substrate Binding Drives Large-Scale Conformational Changes in the Hsp90 Molecular Chaperone

(2011) Timothy O. Street et al.   MOLECULAR CELL

Systematic and Quantitative Assessment of the Ubiquitin-Modified Proteome

(2011) Woong Kim et al.   MOLECULAR CELL

Compartmentalization of Mammalian Folate-Mediated One-Carbon Metabolism

(2010) Anne S. Tibbetts et al.   Annual Review of Nutrition

ALDH1L2 Is the Mitochondrial Homolog of 10-Formyltetrahydrofolate Dehydrogenase

(2010) Natalia I. Krupenko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

(2010) Mikko Taipale et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Quantitative Phosphoproteomics Reveals Widespread Full Phosphorylation Site Occupancy During Mitosis

(2010) J. V. Olsen et al.   Science Signaling

FDH: An aldehyde dehydrogenase fusion enzyme in folate metabolism

(2008) Sergey A. Krupenko   CHEMICO-BIOLOGICAL INTERACTIONS

CHIP deletion reveals functional redundancy of E3 ligases in promoting degradation of both signaling proteins and expanded glutamine proteins

(2008) Y. Morishima et al.   HUMAN MOLECULAR GENETICS

The Phosphatidylinositol 3-Kinase/Akt Cassette Regulates Purine Nucleotide Synthesis

(2008) Wei Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gene Expression Profiling of NF-1-Associated and Sporadic Pilocytic Astrocytoma Identifies Aldehyde Dehydrogenase 1 Family Member L1 (ALDH1L1) as an Underexpressed Candidate Biomarker in Aggressive Subtypes

(2008) Fausto J. Rodriguez et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

(2008) J. D. Cahoy et al.   JOURNAL OF NEUROSCIENCE

Akt and CHIP coregulate tau degradation through coordinated interactions

(2008) C. A. Dickey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA