Mitochondrial dysfunction reduces yeast replicative lifespan by elevating RAS-dependent ROS production by the ER-localized NADPH oxidase Yno1
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Title
Mitochondrial dysfunction reduces yeast replicative lifespan by elevating RAS-dependent ROS production by the ER-localized NADPH oxidase Yno1
Authors
Keywords
Mitochondria, Ras signaling, Phosphorylation, Oxidation, Saccharomyces cerevisiae, Respiratory failure, Yeast, Oxidative damage
Journal
PLoS One
Volume 13, Issue 6, Pages e0198619
Publisher
Public Library of Science (PLoS)
Online
2018-06-19
DOI
10.1371/journal.pone.0198619
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- The Hallmarks of Aging
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- (2013) Jane E. Leadsham et al. Cell Metabolism
- The role of mitochondria in aging
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- Role of peroxisomes in ROS/RNS-metabolism: Implications for human disease
- (2011) Marc Fransen et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Regulation of Yeast Chronological Life Span by TORC1 via Adaptive Mitochondrial ROS Signaling
- (2011) Yong Pan et al. Cell Metabolism
- Mitochondria regulate autophagy by conserved signalling pathways
- (2011) Martin Graef et al. EMBO JOURNAL
- Molecular Mechanisms Regulating Oxidative Activity of the Ero1 Family in the Endoplasmic Reticulum
- (2010) Timothy J. Tavender et al. ANTIOXIDANTS & REDOX SIGNALING
- Life in the midst of scarcity: adaptations to nutrient availability in Saccharomyces cerevisiae
- (2010) Bart Smets et al. CURRENT GENETICS
- Lessons on longevity from budding yeast
- (2010) Matt Kaeberlein NATURE
- Rapamycin increases rDNA stability by enhancing association of Sir2 with rDNA in Saccharomyces cerevisiae
- (2010) Cheol Woong Ha et al. NUCLEIC ACIDS RESEARCH
- Extending Healthy Life Span--From Yeast to Humans
- (2010) L. Fontana et al. SCIENCE
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- (2009) Jeffrey M. Copeland et al. CURRENT BIOLOGY
- Saccharomyces cerevisiae plasma membrane nutrient sensors and their role in PKA signaling
- (2009) Marta Rubio-Texeira et al. FEMS YEAST RESEARCH
- Whi2p links nutritional sensing to actin-dependent Ras-cAMP-PKA regulation and apoptosis in yeast
- (2009) J. E. Leadsham et al. JOURNAL OF CELL SCIENCE
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- (2009) Federico Sesti et al. TRENDS IN CELL BIOLOGY
- Elevated Ras/protein kinase A activity in Saccharomyces cerevisiae reduces proliferation rate and lifespan by two different reactive oxygen species-dependent routes
- (2008) Lydie Hlavatá et al. AGING CELL
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- Selective benefits of damage partitioning in unicellular systems and its effects on aging
- (2008) N. Erjavec et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Chemical Genomic Portrait of Yeast: Uncovering a Phenotype for All Genes
- (2008) M. E. Hillenmeyer et al. SCIENCE
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