Lipophilic statins limit cancer cell growth and survival, via involvement of Akt signaling
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Title
Lipophilic statins limit cancer cell growth and survival, via involvement of Akt signaling
Authors
Keywords
Statins, Breast cancer, Cancer treatment, Ras signaling, ERK signaling cascade, Signal inhibition, Cell growth, Metastasis
Journal
PLoS One
Volume 13, Issue 5, Pages e0197422
Publisher
Public Library of Science (PLoS)
Online
2018-05-16
DOI
10.1371/journal.pone.0197422
References
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- (2014) S E Wheeler et al. BRITISH JOURNAL OF CANCER
- Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion
- (2014) Katsuhiko Warita et al. Scientific Reports
- The PI3K/AKT/mTOR pathway in breast cancer: targets, trials and biomarkers
- (2014) Elisavet Paplomata et al. Therapeutic Advances in Medical Oncology
- The Dormancy Dilemma: Quiescence versus Balanced Proliferation
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- 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults
- (2013) Neil J. Stone et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
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- NCATS launches drug repurposing program
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- Statin Use and Reduced Cancer-Related Mortality
- (2012) Sune F. Nielsen et al. NEW ENGLAND JOURNAL OF MEDICINE
- Statin Prescriptions and Breast Cancer Recurrence Risk: A Danish Nationwide Prospective Cohort Study
- (2011) T. P. Ahern et al. JNCI-Journal of the National Cancer Institute
- Differential Effects of Pravastatin and Simvastatin on the Growth of Tumor Cells from Different Organ Sites
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- Anticancer Efficacy of Simvastatin on Prostate Cancer Cells and Tumor Xenografts Is Associated with Inhibition of Akt and Reduced Prostate-Specific Antigen Expression
- (2010) S. T. Kochuparambil et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Breast carcinoma cells re-express E-cadherin during mesenchymal to epithelial reverting transition
- (2010) Yvonne L Chao et al. Molecular Cancer
- A historical perspective on the discovery of statins
- (2010) Akira ENDO PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES
- Impact of OATP transporters on pharmacokinetics
- (2009) A Kalliokoski et al. BRITISH JOURNAL OF PHARMACOLOGY
- Incidence of cancer and statin usage-Record linkage study
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- The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation
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