Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion

Statins Impair Glucose Uptake in Tumor Cells

(2015) Agata Malenda et al.   NEOPLASIA

Metabolic control of YAP and TAZ by the mevalonate pathway

(2014) Giovanni Sorrentino et al.   NATURE CELL BIOLOGY

Metabolic Modulation of Epigenetics in Gliomas

(2013) Sriram Venneti et al.   BRAIN PATHOLOGY

The Dormancy Dilemma: Quiescence versus Balanced Proliferation

(2013) Alan Wells et al.   CANCER RESEARCH

Modeling Boundary Conditions for Balanced Proliferation in Metastatic Latency

(2013) D. P. Taylor et al.   CLINICAL CANCER RESEARCH

Drug Repurposing: Translational Pharmacology, Chemistry, Computers and the Clinic

(2013) Naiem Issa et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Regulatory Roles of Metabolites in Cell Signaling Networks

(2013) Feng Li et al.   Journal of Genetics and Genomics

Niche-based screening identifies small-molecule inhibitors of leukemia stem cells

(2013) Kimberly A Hartwell et al.   Nature Chemical Biology

Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility

(2013) Z. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition

(2013) M. Yu et al.   SCIENCE

All-human microphysical model of metastasis therapy

(2013) Sarah E Wheeler et al.   Stem Cell Research & Therapy

Biomarker-Guided Repurposing of Chemotherapeutic Drugs for Cancer Therapy: A Novel Strategy in Drug Development

(2013) Jan Stenvang et al.   Frontiers in Oncology

Statins and cancer: Current and future prospects

(2012) Maja Osmak   CANCER LETTERS

Statin Use and Reduced Cancer-Related Mortality

(2012) Sune F. Nielsen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeting tumor cell metabolism with statins

(2012) J W Clendening et al.   ONCOGENE

Mevalonate Metabolism Regulates Basal Breast Cancer Stem Cells and Is a Potential Therapeutic Target

(2012) Christophe Ginestier et al.   STEM CELLS

Lipid raft: A floating island of death or survival

(2012) Kimberly S. George et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The Hippo Transducer TAZ Confers Cancer Stem Cell-Related Traits on Breast Cancer Cells

(2011) Michelangelo Cordenonsi et al.   CELL

Hepatocyte induced re-expression of E-cadherin in breast and prostate cancer cells increases chemoresistance

(2011) Yvonne Chao et al.   CLINICAL & EXPERIMENTAL METASTASIS

The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma

(2011) K. P. L. Bhat et al.   GENES & DEVELOPMENT

Reversible High Affinity Inhibition of Phosphofructokinase-1 by Acyl-CoA

(2011) Christopher M. Jenkins et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal

(2011) Bin Zhao et al.   NATURE CELL BIOLOGY

A Perspective on Cancer Cell Metastasis

(2011) C. L. Chaffer et al.   SCIENCE

The Hippo Signaling Pathway in Development and Cancer

(2010) Duojia Pan   DEVELOPMENTAL CELL

Breast carcinoma cells re-express E-cadherin during mesenchymal to epithelial reverting transition

(2010) Yvonne L Chao et al.   Molecular Cancer

The Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes

(2010) A. J. Levine et al.   SCIENCE

Loss of Membrane Localization and Aberrant Nuclear E-cadherin Expression Correlates With Invasion in Pancreatic Endocrine Tumors

(2009) Runjan Chetty et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

The Association Between Statins and Cancer Incidence in a Veterans Population

(2008) W. R. Farwell et al.   JNCI-Journal of the National Cancer Institute