Ternary copper(II) complex: NCI60 screening, toxicity studies, and evaluation of efficacy in xenograft models of nasopharyngeal carcinoma

Global trends in incidence and mortality of nasopharyngeal carcinoma

(2016) Ling-Ling Tang et al.   CANCER LETTERS

Metal-based drugs that break the rules

(2016) Claire S. Allardyce et al.   DALTON TRANSACTIONS

Current and future potential of metallo drugs: Revisiting DNA-binding of metal containing molecules and their diverse mechanism of action

(2016) Mehvash Zaki et al.   INORGANICA CHIMICA ACTA

Antineoplastic copper coordinated complexes (Casiopeinas) uncouple oxidative phosphorylation and induce mitochondrial permeability transition in cardiac mitochondria and cardiomyocytes

(2016) Christian Silva-Platas et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Synthesis, characterization, and antitumor activity of three ternary dinuclear copper (II) complexes with a reduced Schiff base ligand and diimine coligands in vitro and in vivo

(2016) Lei Jia et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

[Cu(o-phthalate)(phenanthroline)] Exhibits Unique Superoxide-Mediated NCI-60 Chemotherapeutic Action through Genomic DNA Damage and Mitochondrial Dysfunction

(2015) Creina Slator et al.   ACS Chemical Biology

Noble metals in medicine: Latest advances

(2015) Serenella Medici et al.   COORDINATION CHEMISTRY REVIEWS

Antiangiogenic Activity of Mononuclear Copper(II) Polypyridyl Complexes for the Treatment of Cancers

(2015) Penumaka Nagababu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antitumor mechanisms of a copper(ii) complex of anthracene-9-imidazoline hydrazone (9-AIH)

(2015) Qi-Pin Qin et al.   Metallomics

Homoleptic phosphino copper(i) complexes with in vitro and in vivo dual cytotoxic and anti-angiogenic activity

(2015) V. Gandin et al.   Metallomics

Targeting copper in cancer therapy: ‘Copper That Cancer’

(2015) Delphine Denoyer et al.   Metallomics

Se-methylselenocysteine offers selective protection against toxicity and potentiates the antitumour activity of anticancer drugs in preclinical animal models

(2014) S Cao et al.   BRITISH JOURNAL OF CANCER

Quinine Compared to 4β-Hydroxycholesterol and Midazolam as Markers for CYP3A Induction by Rifampicin

(2014) Linda Björkhem-Bergman et al.   Drug Metabolism and Pharmacokinetics

Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in p53

(2014) G. L. Kelly et al.   GENES & DEVELOPMENT

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

A comprehensive biological insight of trinuclear copper(ii)–tin(iv) chemotherapeutic anticancer drug entity: in vitro cytotoxicity and in vivo systemic toxicity studies

(2014) Yusra Zaidi et al.   Metallomics

Selective anticancer copper(ii)-mixed ligand complexes: targeting of ROS and proteasomes

(2014) Chew Hee Ng et al.   Metallomics

Cellular Transport Mechanisms of Cytotoxic Metallodrugs: An Overview beyond Cisplatin

(2014) Sarah Spreckelmeyer et al.   MOLECULES

Inhibitory effects of dioscin on cytochrome P450 enzymes

(2014) Xufeng Tao et al.   RSC Advances

Organometallic Iridium(III) Anticancer Complexes with New Mechanisms of Action: NCI-60 Screening, Mitochondrial Targeting, and Apoptosis

(2013) Jessica M. Hearn et al.   ACS Chemical Biology

Advances in Copper Complexes as Anticancer Agents

(2013) Carlo Santini et al.   CHEMICAL REVIEWS

In Vitro and in Vivo Anticancer Activity of Copper Bis(thiosemicarbazone) Complexes

(2013) Duraippandi Palanimuthu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pre-treatment with cardamonin protects against cisplatin-induced nephrotoxicity in rats: Impact on NOX-1, inflammation and apoptosis

(2013) Reem N. El-Naga   TOXICOLOGY AND APPLIED PHARMACOLOGY

Targeted therapy vs. DNA-adduct formation-guided design: thoughts about the future of metal-based anticancer drugs

(2012) Gianni Sava et al.   DALTON TRANSACTIONS

Current Management of Nasopharyngeal Cancer

(2012) Anne W.M. Lee et al.   SEMINARS IN RADIATION ONCOLOGY

In vitro models for liver toxicity testing

(2012) Valerie Y. Soldatow et al.   Toxicology Research

The status of platinum anticancer drugs in the clinic and in clinical trials

(2010) Nial J. Wheate et al.   DALTON TRANSACTIONS

In vivo and in vitro evaluation of highly specific thiolate carrier group copper(II) and zinc(II) complexes on Ehrlich ascites carcinoma tumor model

(2010) N. Raman et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Analysis of Food and Drug Administration-Approved Anticancer Agents in the NCI60 Panel of Human Tumor Cell Lines

(2010) S. L. Holbeck et al.   MOLECULAR CANCER THERAPEUTICS

Persistent induction of cytochrome P450 (CYP)1A enzymes by 3-methylcholanthrene in vivo in mice is mediated by sustained transcriptional activation of the corresponding promoters

(2009) Weiwu Jiang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Development of Idarubicin and Doxorubicin Solid Lipid Nanoparticles to Overcome Pgp-Mediated Multiple Drug Resistance in Leukemia

(2009) Ping Ma et al.   Journal of Biomedical Nanotechnology