Identification and functional analysis of SOX10 phosphorylation sites in melanoma

Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly dividing de‐differentiated state

(2017) Mohammad Fallahi‐Sichani et al.   Molecular Systems Biology

Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance

(2017) Sydney M. Shaffer et al.   NATURE

BRG1 interacts with SOX10 to establish the melanocyte lineage and to promote differentiation

(2017) Himangi G. Marathe et al.   NUCLEIC ACIDS RESEARCH

SoxE factors: Transcriptional regulators of neural differentiation and nervous system development

(2017) Matthias Weider et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Identification of upstream transcription factors (TFs) for expression signature genes in breast cancer

(2016) Hongyan Zang et al.   GYNECOLOGICAL ENDOCRINOLOGY

Proteogenomics connects somatic mutations to signalling in breast cancer

(2016) Philipp Mertins et al.   NATURE

Chd7 cooperates with Sox10 and regulates the onset of CNS myelination and remyelination

(2016) Danyang He et al.   NATURE NEUROSCIENCE

TGF-β regulates phosphorylation and stabilization of Sox9 protein in chondrocytes through p38 and Smad dependent mechanisms

(2016) George Coricor et al.   Scientific Reports

Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes

(2015) Temesgen D. Fufa et al.   HUMAN MOLECULAR GENETICS

A Phosphoproteomic Comparison of B-RAFV600Eand MKK1/2 Inhibitors in Melanoma Cells

(2015) Scott A. Stuart et al.   MOLECULAR & CELLULAR PROTEOMICS

SLUG is required for SOX9 stabilization and functions to promote cancer stem cells and metastasis in human lung carcinoma

(2015) S Luanpitpong et al.   ONCOGENE

MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells

(2015) Diego Ploper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SOXE transcription factors form selective dimers on non-compact DNA motifs through multifaceted interactions between dimerization and high-mobility group domains

(2015) Yong-Heng Huang et al.   Scientific Reports

Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation

(2015) Hyungsoo Kim et al.   Cell Reports

Sox10 Regulates Stem/Progenitor and Mesenchymal Cell States in Mammary Epithelial Cells

(2015) Christopher Dravis et al.   Cell Reports

Antagonistic Cross-Regulation between Sox9 and Sox10 Controls an Anti-tumorigenic Program in Melanoma

(2015) Olga Shakhova et al.   PLoS Genetics

Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells

(2015) Patrick Laurette et al.   eLife

Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma

(2014) Chong Sun et al.   NATURE

Phosphorylation of PAX3 contributes to melanoma phenotypes by affecting proliferation, invasion, and transformation

(2014) Aditi S. Iyengar et al.   Pigment Cell & Melanoma Research

Regulation of transcription factor activity by interconnected post-translational modifications

(2014) Theresa M. Filtz et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

SOX10 is a novel oncogene in hepatocellular carcinoma through Wnt/β-catenin/TCF4 cascade

(2014) Dangjun Zhou et al.   TUMOR BIOLOGY

BRAF Mutations in Metastatic Malignant Melanoma

(2014) Laleh Ehsani et al.   APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY

Diagnostic SOX10 gene signatures in salivary adenoid cystic and breast basal-like carcinomas

(2013) S V Ivanov et al.   BRITISH JOURNAL OF CANCER

SOX10 Ablation Arrests Cell Cycle, Induces Senescence, and Suppresses Melanomagenesis

(2013) J. C. Cronin et al.   CANCER RESEARCH

MAP Kinase Pathway Alterations in BRAF-Mutant Melanoma Patients with Acquired Resistance to Combined RAF/MEK Inhibition

(2013) N. Wagle et al.   Cancer Discovery

Concurrent MEK2 Mutation and BRAF Amplification Confer Resistance to BRAF and MEK Inhibitors in Melanoma

(2013) Jessie Villanueva et al.   Cell Reports

A Landscape of Driver Mutations in Melanoma

(2012) Eran Hodis et al.   CELL

Neural crest transcription factor Sox10 is preferentially expressed in triple-negative and metaplastic breast carcinomas

(2012) Ashley Cimino-Mathews et al.   HUMAN PATHOLOGY

The role of BRAF V600 mutation in melanoma

(2012) Paolo A Ascierto et al.   Journal of Translational Medicine

Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma

(2012) Olga Shakhova et al.   NATURE CELL BIOLOGY

Cell cycle and aging, morphogenesis, and response to stimuli genes are individualized biomarkers of glioblastoma progression and survival

(2011) Nicola VL Serão et al.   BMC Medical Genomics

Identification and functional analysis ofSOX10missense mutations in different subtypes of waardenburg syndrome

(2011) Asma Chaoui et al.   HUMAN MUTATION

Spatial Phosphoprotein Profiling Reveals a Compartmentalized Extracellular Signal-regulated Kinase Switch Governing Neurite Growth and Retraction

(2011) Yingchun Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dissecting Therapeutic Resistance to RAF Inhibition in Melanoma by Tumor Genomic Profiling

(2011) Nikhil Wagle et al.   JOURNAL OF CLINICAL ONCOLOGY

Review and update of mutations causing Waardenburg syndrome

(2010) Véronique Pingault et al.   HUMAN MUTATION

Incidence of the V600K mutation among melanoma patients with BRAF mutations, and potential therapeutic response to the specific BRAF inhibitor PLX4032

(2010) Jill C Rubinstein et al.   Journal of Translational Medicine

Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

(2010) Ramin Nazarian et al.   NATURE

Sox proteins in melanocyte development and melanoma

(2010) Melissa L. Harris et al.   Pigment Cell & Melanoma Research

SoxE factors as multifunctional neural crest regulatory factors

(2009) Caroline E. Haldin et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Large-scale Proteomics Analysis of the Human Kinome

(2009) Felix S. Oppermann et al.   MOLECULAR & CELLULAR PROTEOMICS

The Transcriptional Activity of Sox9 in Chondrocytes Is Regulated by RhoA Signaling and Actin Polymerization

(2009) D. Kumar et al.   MOLECULAR AND CELLULAR BIOLOGY

Functional Proteomics Identifies Targets of Phosphorylation by B-Raf Signaling in Melanoma

(2009) William M. Old et al.   MOLECULAR CELL

Frequent mutations in the MITF pathway in melanoma

(2009) Julia C. Cronin et al.   Pigment Cell & Melanoma Research

Solid Tumor Proteome and Phosphoproteome Analysis by High Resolution Mass Spectrometry

(2008) Sara Zanivan et al.   JOURNAL OF PROTEOME RESEARCH