Bidesmosidic betulin saponin bearing L-rhamnopyranoside moieties induces apoptosis and inhibition of lung cancer cells growth in vitro and in vivo

Escin induces apoptosis in human renal cancer cells through G2/M arrest and reactive oxygen species-modulated mitochondrial pathways

(2017) Sheau-Yun Yuan et al.   ONCOLOGY REPORTS

A novel cycloartane triterpenoid from Cimicifuga induces apoptotic and autophagic cell death in human colon cancer HT-29 cells

(2017) Xiaoli Dai et al.   ONCOLOGY REPORTS

Mitochondria and Cancer

(2016) Wei-Xing Zong et al.   MOLECULAR CELL

Betulinic Acid: Recent Advances in Chemical Modifications, Effective Delivery, and Molecular Mechanisms of a Promising Anticancer Therapy

(2015) Mohamed Ali-Seyed et al.   Chemical Biology & Drug Design

Improving Physical Properties via CH Oxidation: Chemical and Enzymatic Approaches

(2014) Quentin Michaudel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Synthetic Triterpenoid CDDO-Im Inhibits Tumorsphere Formation by Regulating Stem Cell Signaling Pathways in Triple-Negative Breast Cancer

(2014) Jae Young So et al.   PLoS One

Development and Characterisation of Ursolic Acid Nanocrystals Without Stabiliser Having Improved Dissolution Rate and In Vitro Anticancer Activity

(2013) Ju Song et al.   AAPS PHARMSCITECH

Biological evaluation of morin and its new oxovanadium(IV) complex as antio-xidant and specific anti-cancer agents

(2013) Luciana G. Naso et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Synthesis, Structure and Cytotoxic Activity of New Acetylenic Derivatives of Betulin

(2013) Stanisław Boryczka et al.   MOLECULES

Natural products as leads to antitumor drugs

(2013) David J. Newman et al.   PHYTOCHEMISTRY REVIEWS

Cytosolic and mitochondrial ROS: which one is associated with poor chromatin remodeling?

(2013) Abbas Kiani-Esfahani et al.   Systems Biology in Reproductive Medicine

Caspase Functions in Cell Death and Disease

(2013) D. R. McIlwain et al.   Cold Spring Harbor Perspectives in Biology

How apoptotic cells aid in the removal of their own cold dead bodies

(2012) G Wickman et al.   CELL DEATH AND DIFFERENTIATION

Natural products for cancer chemotherapy

(2010) Arnold L. Demain et al.   Microbial Biotechnology

Betulin Elicits Anti-Cancer Effects in Tumour Primary Cultures and Cell LinesIn Vitro

(2009) Wojciech Rzeski et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Haemolytic activity, cytotoxicity and membrane cell permeabilization of semi-synthetic and natural lupane- and oleanane-type saponins

(2009) Charles Gauthier et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Effect of staurosporine on the mobility and invasiveness of lung adenocarcinoma A549 cells: an in vitro study

(2009) Yanyan Wang et al.   BMC CANCER

Comparision of the Cytotoxic Effects of Birch Bark Extract, Betulin and Betulinic Acid Towards Human Gastric Carcinoma and Pancreatic Carcinoma Drug-sensitive and Drug-Resistant Cell Lines

(2009) Marcin Drag et al.   MOLECULES

Betulinic Acid for Cancer Treatment and Prevention

(2008) Simone Fulda   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Synthesis and Cytotoxicity of Bidesmosidic Betulin and Betulinic Acid Saponins

(2008) Charles Gauthier et al.   JOURNAL OF NATURAL PRODUCTS