Characterization of broadly neutralizing antibody responses to HIV-1 in a cohort of long term non-progressors

Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller

(2017) Natalia T. Freund et al.   Science Translational Medicine

Detection of Broadly Neutralizing Activity within the First Months of HIV-1 Infection

(2016) V. Sanchez-Merino et al.   JOURNAL OF VIROLOGY

Broadly Neutralizing HIV Antibodies Define a Glycan-Dependent Epitope on the Prefusion Conformation of gp41 on Cleaved Envelope Trimers

(2014) Emilia Falkowska et al.   IMMUNITY

Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers

(2014) Claudia Blattner et al.   IMMUNITY

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface

(2014) Jinghe Huang et al.   NATURE

Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike

(2014) Louise Scharf et al.   Cell Reports

Prevalence of broadly neutralizing antibody responses during chronic HIV-1 infection

(2013) Peter Hraber et al.   AIDS

Delineating Antibody Recognition in Polyclonal Sera from Patterns of HIV-1 Isolate Neutralization

(2013) I. S. Georgiev et al.   SCIENCE

Expansion of HIV-specific T follicular helper cells in chronic HIV infection

(2012) Madelene Lindqvist et al.   JOURNAL OF CLINICAL INVESTIGATION

Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein

(2012) Florian Klein et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production

(2012) Matthieu Perreau et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Magnitude and Breadth of the Neutralizing Antibody Response in the RV144 and Vax003 HIV-1 Vaccine Efficacy Trials

(2012) D. C. Montefiori et al.   JOURNAL OF INFECTIOUS DISEASES

Two Distinct Broadly Neutralizing Antibody Specificities of Different Clonal Lineages in a Single HIV-1-Infected Donor: Implications for Vaccine Design

(2012) Mattia Bonsignori et al.   JOURNAL OF VIROLOGY

The Development of CD4 Binding Site Antibodies during HIV-1 Infection

(2012) R. M. Lynch et al.   JOURNAL OF VIROLOGY

Straightforward Selection of Broadly Neutralizing Single-Domain Antibodies Targeting the Conserved CD4 and Coreceptor Binding Sites of HIV-1 gp120

(2012) J. Matz et al.   JOURNAL OF VIROLOGY

Broad and potent neutralization of HIV-1 by a gp41-specific human antibody

(2012) Jinghe Huang et al.   NATURE

Evolution of Cross-Neutralizing Antibody Specificities to the CD4-BS and the Carbohydrate Cloak of the HIV Env in an HIV-1-Infected Subject

(2012) Iliyana Mikell et al.   PLoS One

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

Broadly Cross-Neutralizing Antibodies in HIV-1 Patients with Undetectable Viremia

(2011) M. Medina-Ramirez et al.   JOURNAL OF VIROLOGY

Analysis of a Clonal Lineage of HIV-1 Envelope V2/V3 Conformational Epitope-Specific Broadly Neutralizing Antibodies and Their Inferred Unmutated Common Ancestors

(2011) M. Bonsignori et al.   JOURNAL OF VIROLOGY

Polyclonal B Cell Responses to Conserved Neutralization Epitopes in a Subset of HIV-1-Infected Individuals

(2011) G. D. Tomaras et al.   JOURNAL OF VIROLOGY

Broad neutralization coverage of HIV by multiple highly potent antibodies

(2011) Laura M. Walker et al.   NATURE

Characterization of Neutralizing Profiles in HIV-1 Infected Patients from whom the HJ16, HGN194 and HK20 mAbs were Obtained

(2011) Sunita S. Balla-Jhagjhoorsingh et al.   PLoS One

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

(2011) X. Wu et al.   SCIENCE

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

(2011) J. F. Scheid et al.   SCIENCE

Short Communication: Biological and Genetic Characterization of HIV Type 1 Subtype B and Nonsubtype B Transmitted Viruses: Usefulness for Vaccine Candidate Assessment

(2010) M.T. Cuevas et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

A sensitive phenotypic assay for the determination of human immunodeficiency virus type 1 tropism

(2010) N. Gonzalez et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Crystal Structure of PG16 and Chimeric Dissection with Somatically Related PG9: Structure-Function Analysis of Two Quaternary-Specific Antibodies That Effectively Neutralize HIV-1

(2010) M. Pancera et al.   JOURNAL OF VIROLOGY

Analysis of Memory B Cell Responses and Isolation of Novel Monoclonal Antibodies with Neutralizing Breadth from HIV-1-Infected Individuals

(2010) Davide Corti et al.   PLoS One

Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

(2010) T. Zhou et al.   SCIENCE

Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1

(2010) X. Wu et al.   SCIENCE

A Limited Number of Antibody Specificities Mediate Broad and Potent Serum Neutralization in Selected HIV-1 Infected Individuals

(2010) Laura M. Walker et al.   PLoS Pathogens

Breadth of Human Immunodeficiency Virus-Specific Neutralizing Activity in Sera: Clustering Analysis and Association with Clinical Variables

(2009) N. A. Doria-Rose et al.   JOURNAL OF VIROLOGY

Breadth of Neutralizing Antibody Response to Human Immunodeficiency Virus Type 1 Is Affected by Factors Early in Infection but Does Not Influence Disease Progression

(2009) A. Piantadosi et al.   JOURNAL OF VIROLOGY

International Network for Comparison of HIV Neutralization Assays: The NeutNet Report

(2009) Eva Maria Fenyö et al.   PLoS One

The Spanish HIV BioBank: a model of cooperative HIV research

(2009) Isabel Garcia-Merino et al.   Retrovirology

Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target

(2009) L. M. Walker et al.   SCIENCE

Affinity maturation by targeted diversification of the CDR-H2 loop of a monoclonal Fab derived from a synthetic naïve human antibody library and directed against the internal trimeric coiled-coil of gp41 yields a set of Fabs with improved HIV-1 neutralization potency and breadth

(2009) Elena Gustchina et al.   VIROLOGY

Factors Associated with the Development of Cross-Reactive Neutralizing Antibodies during Human Immunodeficiency Virus Type 1 Infection

(2008) D. N. Sather et al.   JOURNAL OF VIROLOGY

Analysis of Neutralization Specificities in Polyclonal Sera Derived from Human Immunodeficiency Virus Type 1-Infected Individuals

(2008) Y. Li et al.   JOURNAL OF VIROLOGY